Results 111 to 120 of about 4,530 (193)

Data for amino acid alignment of Japanese stingray melanocortin receptors with other gnathostome melanocortin receptor sequences, and the ligand selectivity of Japanese stingray melanocortin receptors

open access: yesData in Brief, 2016
This article contains structure and pharmacological characteristics of melanocortin receptors (MCRs) related to research published in “Characterization of melanocortin receptors from stingray Dasyatis akajei, a cartilaginous fish” (Takahashi et al., 2016)
Akiyoshi Takahashi   +5 more
doaj   +1 more source

Anti-melanocortin-4 receptor autoantibodies in obesity [PDF]

open access: yes, 2009
Background: The melanocortin-4 receptor (MC4R) is part of an important pathway regulating energy balance. Here we report the existence of autoantibodies (autoAbs) against the MC4R in sera of obese patients.
Bekel, A.   +9 more
core   +3 more sources

The Importance of Melanocortin Receptors and Their Agonists in Pulmonary Disease

open access: yesFrontiers in Medicine, 2019
Melanocortin agonists are ancient neuropeptides that have steroidogenesis and anti-inflammatory properties. They activate melanocortin receptors (MCR), a family of five seven-transmembrane G-protein coupled receptors. MC1R and MC3R are mainly involved in
Anna Elizabeth Moscowitz   +6 more
doaj   +1 more source

Feinkartierung einer Kopplungsregion auf Chromosom 10p für frühmanifeste Adipositas mittels sieben Mikrosatellitenmarkern an 123 Familien bestehend aus mindestens zwei adipösen Geschwistern und ihren Eltern. [PDF]

open access: yes, 2002
Im Rahmen der Suche nach genetischen Ursachen des komplexen Phänotyps Adipositas wurde von einer französischen Arbeitsgruppe eine Kopplungsregion für extreme Adipositas auf Chromosom 10p12 identifiziert (Hager et al. 1998).
Hebebrand, Johannes Prof. Dr. med.   +1 more
core   +1 more source

Heterogeneous network embedding enabling accurate disease association predictions. [PDF]

open access: yes, 2019
BackgroundIt is significant to identificate complex biological mechanisms of various diseases in biomedical research. Recently, the growing generation of tremendous amount of data in genomics, epigenomics, metagenomics, proteomics, metabolomics ...
A Bordes   +40 more
core   +2 more sources

Observations on the evolution of the melanocortin receptor gene family: distinctive features of the melanocortin-2 receptor

open access: yesFrontiers in Neuroscience, 2013
The melanocortin receptors are a gene family in the rhodopsin class of G protein-coupled receptors. Based on the analysis of several metazoan genome databases it appears that the melanocortin receptors are only found in chordates.
Robert Michael Dores
doaj   +1 more source

Promiscuity among the MRAPs. [PDF]

open access: yes, 2017
The melanocortin 2 receptor accessory protein (MRAP) was originally discovered to be an essential co-receptor for the ACTH receptor/melanocortin 2 receptor, and it physically interacts with this receptor and is required for receptor trafficking and ...
Chan, LF, Clark, AJL
core   +1 more source

Central regulation of food intake and reproduction

open access: yes, 2011
The work described in this thesis investigates the actions of hypothalamic neuropeptides involved in the control of energy homeostasis and reproduction.
Beale, Kylie Emma Louise   +1 more
core   +1 more source

Evolution of sex-specific pace-of-life syndromes: genetic architecture and physiological mechanisms [PDF]

open access: yes, 2018
Sex differences in life history, physiology, and behavior are nearly ubiquitous across taxa, owing to sex-specific selection that arises from different reproductive strategies of the sexes.
A Bendesky   +279 more
core   +2 more sources

Physiogenomic comparison of human fat loss in response to diets restrictive of carbohydrate or fat [PDF]

open access: yes, 2008
Background Genetic factors that predict responses to diet may ultimately be used to individualize dietary recommendations. We used physiogenomics to explore associations among polymorphisms in candidate genes and changes in relative body fat (Δ%BF) to ...
Richard L Seip   +81 more
core   +1 more source

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