Results 61 to 70 of about 1,780 (172)
Objective To evaluate if children with ASD, or mothers of ASD children have elevated CRP during pregnancy. Background Autism spectrum disorder (ASD) is a neuro developmental disorder with incidence of 1 in 68 children occur in all racial, ethnic, and ...
Rashid Nadeem +2 more
doaj +1 more source
Abstract INTRODUCTION The relationship between peripheral vascular health, including endothelia, cognitive decline, and Alzheimer's disease (AD) dementia risk is unclear. METHODS In this study, 2844 dementia‐free Framingham Offspring participants (mean age 60.6 years, 53.2% women) had baseline brachial artery flow‐mediated dilation (FMD%) and reactive ...
Qiushan Tao +15 more
wiley +1 more source
In vitro generation and bioactivity evaluation of C-reactive protein intermediate. [PDF]
The conformational conversion of pentameric C-reactive protein (pCRP) to monomeric CRP (mCRP) has been shown to play important roles in the action of CRP in inflammation regulation.
Jian-Min Lv, Ming-Yu Wang
doaj +1 more source
IntroductionElevated C-reactive protein (CRP) is a hallmark of rheumatoid arthritis (RA) flares. CRP exists as pentameric (pCRP) and monomeric (mCRP) isoforms with distinct functions, with pCRP generally pro-inflammatory and mCRP more immunomodulatory ...
Alexia Correia Ferreira +10 more
doaj +1 more source
ABSTRACT Tools based on multi‐criteria decision analysis (MCDA) can be used in decision‐making processes related to food safety issues (FSI). We used risk–benefit analysis (RBA) and the analytic hierarchy process (AHP) to answer the following questions: What are the benefits and risks of using rapid Salmonella assays in large‐scale poultry industries ...
Cris Rocha Pinto Magalhães +2 more
wiley +1 more source
mCRP binds to U937 monocytic cells, and induces robust chemotaxis in an integrin-dependent manner.
a). Adhesion of U937 cells to CRP isoforms. Wells of 96 well microtiter plate were coated with mCRP or pCRP and remaining protein-binding sites were blocked with BSA. Wells were incubated with U937 cells (105 cells per well) for 1 h in RPMI1640 and bound
Yoko K. Takada (365353) +3 more
core +1 more source
The objective of this work was to study the ability of blood cells and their microparticles to transport monomeric and pentameric forms of C-reactive protein (mCRP and pCRP) in the blood of patients with coronary artery disease (CAD).
Ivan Melnikov +11 more
doaj +1 more source
The differing roles of the pentameric (p) and monomeric (m) C-reactive protein (CRP) isoforms in viral diseases are not fully understood, which was apparent during the COVID-19 pandemic regarding the clinical course of severe acute respiratory syndrome ...
Francis R. Hopkins +16 more
doaj +1 more source
Abstract Acute promyelocytic leukemia (APL) is a medical emergency that needs immediate diagnosis and treatment. Podoplanin, a transmembrane glycoprotein that binds CLEC‐2 on platelets, was recently demonstrated to be abnormally expressed in leukemic blasts in APL, as opposed to other forms of AML, in a study using thawed primary cells.
Camilla Maria de Alencar Saraiva +7 more
wiley +1 more source
Resveratrol is a natural phenolic compound with known benefits against neurodegeneration. We analyzed in vitro the protective mechanisms of resveratrol against the proinflammatory monomeric C-reactive protein (mCRP).
Clara Bartra +8 more
doaj +1 more source

