Results 61 to 70 of about 3,242 (179)

A Base‐Free Two‐Coordinate Oxoborane

Angewandte Chemie, Volume 137, Issue 7, February 10, 2025.
A base‐free, two coordinate oxoborane (R‐BO) has been isolated as a Lewis adduct with AlCl3 and shown to react in a unique way with PhN3. In contrast to the parent oxoborane, the oxoborane→AlCl3 adduct is stable towards oligomerisation and C−H cleavage of the Mes* group as AlCl3 coordination provides thermodynamic stabilization while also reducing the ...
Clement R. P. Millet, Dominic R. Willcox, Gary S. Nichol, Cate S. Anstöter, Michael J. Ingleson   +4 more
wiley   +2 more sources

Using Risk–Benefit Analysis and the Analytical Hierarchy Process to Decide on the Implementation of Rapid Salmonella Detection Methods in Large Poultry Industries

Risk Analysis, Volume 46, Issue 4, April 2026.
ABSTRACT Tools based on multi‐criteria decision analysis (MCDA) can be used in decision‐making processes related to food safety issues (FSI). We used risk–benefit analysis (RBA) and the analytic hierarchy process (AHP) to answer the following questions: What are the benefits and risks of using rapid Salmonella assays in large‐scale poultry industries ...
Cris Rocha Pinto Magalhães, Nathanyelle Soraya Martins de Aquino, Eduardo Cesar Tondo   +2 more
wiley   +1 more source

A biofunctional review of C-reactive protein (CRP) as a mediator of inflammatory and immune responses: differentiating pentameric and modified CRP isoform effects

Frontiers in Immunology, 2023
C-reactive protein (CRP) is an acute phase, predominantly hepatically synthesized protein, secreted in response to cytokine signaling at sites of tissue injury or infection with the physiological function of acute pro-inflammatory response. Historically,
Margaret E. Olson, Mary G. Hornick, Ashley Stefanski, Haya R. Albanna, Alesia Gjoni, Griffin D. Hall, Peter C. Hart, Ibraheem M. Rajab, Lawrence A. Potempa   +8 more
doaj   +1 more source

Prospective validation of podoplanin expression as a diagnostic biomarker of acute promyelocytic leukemia

Cytometry Part B: Clinical Cytometry, Volume 110, Issue 2, Page 128-133, March 2026.
Abstract Acute promyelocytic leukemia (APL) is a medical emergency that needs immediate diagnosis and treatment. Podoplanin, a transmembrane glycoprotein that binds CLEC‐2 on platelets, was recently demonstrated to be abnormally expressed in leukemic blasts in APL, as opposed to other forms of AML, in a study using thawed primary cells.
Camilla Maria de Alencar Saraiva, Carla Roberta Peachazepi Moraes, Bruno Kosa Lino Duarte, Gislaine Borba Oliveira, Herton Luiz Alves Sales Filho, Paula de Melo Campos, Sara Teresinha Olalla Saad, Erich Vinicius De Paula   +7 more
wiley   +1 more source

C reactive protein elevation among children or among mothers’ of children with autism during pregnancy, a review and meta-analysis

BMC Psychiatry, 2020
Objective To evaluate if children with ASD, or mothers of ASD children have elevated CRP during pregnancy. Background Autism spectrum disorder (ASD) is a neuro developmental disorder with incidence of 1 in 68 children occur in all racial, ethnic, and ...
Rashid Nadeem, Tamseela Hussain, Hassan Sajid   +2 more
doaj   +1 more source

Companion Diagnostics in Clinical Therapy: Current Applications and Future Directions

MedComm, Volume 7, Issue 3, March 2026.
Companion diagnostics use biomarker‐based assays to stratify patients for precision therapies, improving outcomes while reducing ineffective treatment and side effects. This review summarizes the evolution, regulatory landscape, clinical applications, and technological platforms of CDx, highlighting their role in biomarker‐driven precision therapy.
Yuesong Wu, Rou Xue, Xiangwen Luo, Jiangnan Liao, Zongbo Zhang, Jinhai Deng, Teng Liu, Xin Li, Zhe‐Sheng Chen, Mingzhu Yin   +9 more
wiley   +1 more source

Downregulating Platelet Endothelial Cell Adhesion Molecule‐1 Enhances Learning and Memory and Alleviates Hallmark Pathologies in Alzheimer's Disease

MedComm, Volume 7, Issue 3, March 2026.
CD31 upregulation in 5xFAD mice activates STAT1/Irf1 signaling, driving abnormal gene transcription, Aβ and tau accumulation, microglial activation, and neuroinflammation, leading to cognitive decline. Systemic CD31 knockdown suppresses STAT1/Irf1 activity, restores gene expression balance, reduces Aβ and tau pathologies, alleviates neuroinflammation ...
Qiuzhi Zhou, Fei Sun, Yao Zhang, Xiaojian Cao, Mengzhu Li, Haitao Yu, Tao Jiang, Shihong Li, Weixia Wang, Jiazhao Xie, Ting He, Yanchao Liu, Xiuping Liu, Ying Yang, Dan Ke, Xiao‐Chuan Wang, Enjie Liu, Jian‐Zhi Wang   +17 more
wiley   +1 more source

Impact of Endodontic Treatment of Teeth With Apical Periodontitis on Levels of Inflammatory Biomarkers Associated With Cardiovascular Risk: A Systematic Review and Meta‐Analysis

The Scientific World Journal, Volume 2026, Issue 1, 2026.
Background Apical periodontitis (AP) is an inflammatory response to microbial infection of the root canal system. The microorganisms that cause AP can modulate the host’s immune response by secreting inflammatory biomarkers, which might be associated with cardiovascular diseases.
Carolina Viana Vasco Lyra, Jéssica Meirinhos Miranda, Renata de Albuquerque Cavalcanti Almeida, Marina da Cunha Isaltino, Ana Virginia Silva Vilela, Marleny Elizabeth Márquez de Martínez Gerbi, Diana Santana de Albuquerque, Natália Gomes de Oliveira, Dariusz Chlubek   +8 more
wiley   +1 more source

CRP Is Transported by Monocytes and Monocyte-Derived Exosomes in the Blood of Patients with Coronary Artery Disease

Biomedicines, 2020
The objective of this work was to study the ability of blood cells and their microparticles to transport monomeric and pentameric forms of C-reactive protein (mCRP and pCRP) in the blood of patients with coronary artery disease (CAD).
Ivan Melnikov, Sergey Kozlov, Olga Saburova, Ekaterina Zubkova, Olga Guseva, Sergey Domogatsky, Tatiana Arefieva, Natalia Radyukhina, Maria Zvereva, Yuliya Avtaeva, Lyudmila Buryachkovskaya, Zufar Gabbasov   +11 more
doaj   +1 more source

In vitro generation and bioactivity evaluation of C-reactive protein intermediate. [PDF]

PLoS ONE, 2018
The conformational conversion of pentameric C-reactive protein (pCRP) to monomeric CRP (mCRP) has been shown to play important roles in the action of CRP in inflammation regulation.
Jian-Min Lv, Ming-Yu Wang
doaj   +1 more source