Results 61 to 70 of about 1,780 (172)

C reactive protein elevation among children or among mothers’ of children with autism during pregnancy, a review and meta-analysis

open access: yesBMC Psychiatry, 2020
Objective To evaluate if children with ASD, or mothers of ASD children have elevated CRP during pregnancy. Background Autism spectrum disorder (ASD) is a neuro developmental disorder with incidence of 1 in 68 children occur in all racial, ethnic, and ...
Rashid Nadeem   +2 more
doaj   +1 more source

Peripheral vascular function, including endothelium‐dependent measures, and dementia risk: The Framingham Heart Study

open access: yesAlzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION The relationship between peripheral vascular health, including endothelia, cognitive decline, and Alzheimer's disease (AD) dementia risk is unclear. METHODS In this study, 2844 dementia‐free Framingham Offspring participants (mean age 60.6 years, 53.2% women) had baseline brachial artery flow‐mediated dilation (FMD%) and reactive ...
Qiushan Tao   +15 more
wiley   +1 more source

In vitro generation and bioactivity evaluation of C-reactive protein intermediate. [PDF]

open access: yesPLoS ONE, 2018
The conformational conversion of pentameric C-reactive protein (pCRP) to monomeric CRP (mCRP) has been shown to play important roles in the action of CRP in inflammation regulation.
Jian-Min Lv, Ming-Yu Wang
doaj   +1 more source

Monomeric CRP is prevalent in the blood of patients with rheumatoid arthritis and correlates with clinically relevant markers

open access: yesFrontiers in Immunology
IntroductionElevated C-reactive protein (CRP) is a hallmark of rheumatoid arthritis (RA) flares. CRP exists as pentameric (pCRP) and monomeric (mCRP) isoforms with distinct functions, with pCRP generally pro-inflammatory and mCRP more immunomodulatory ...
Alexia Correia Ferreira   +10 more
doaj   +1 more source

Using Risk–Benefit Analysis and the Analytical Hierarchy Process to Decide on the Implementation of Rapid Salmonella Detection Methods in Large Poultry Industries

open access: yesRisk Analysis, Volume 46, Issue 4, April 2026.
ABSTRACT Tools based on multi‐criteria decision analysis (MCDA) can be used in decision‐making processes related to food safety issues (FSI). We used risk–benefit analysis (RBA) and the analytic hierarchy process (AHP) to answer the following questions: What are the benefits and risks of using rapid Salmonella assays in large‐scale poultry industries ...
Cris Rocha Pinto Magalhães   +2 more
wiley   +1 more source

mCRP binds to U937 monocytic cells, and induces robust chemotaxis in an integrin-dependent manner.

open access: yes, 2014
a). Adhesion of U937 cells to CRP isoforms. Wells of 96 well microtiter plate were coated with mCRP or pCRP and remaining protein-binding sites were blocked with BSA. Wells were incubated with U937 cells (105 cells per well) for 1 h in RPMI1640 and bound
Yoko K. Takada (365353)   +3 more
core   +1 more source

CRP Is Transported by Monocytes and Monocyte-Derived Exosomes in the Blood of Patients with Coronary Artery Disease

open access: yesBiomedicines, 2020
The objective of this work was to study the ability of blood cells and their microparticles to transport monomeric and pentameric forms of C-reactive protein (mCRP and pCRP) in the blood of patients with coronary artery disease (CAD).
Ivan Melnikov   +11 more
doaj   +1 more source

Pentameric C-reactive protein is a better prognostic biomarker and remains elevated for longer than monomeric CRP in hospitalized patients with COVID-19

open access: yesFrontiers in Immunology, 2023
The differing roles of the pentameric (p) and monomeric (m) C-reactive protein (CRP) isoforms in viral diseases are not fully understood, which was apparent during the COVID-19 pandemic regarding the clinical course of severe acute respiratory syndrome ...
Francis R. Hopkins   +16 more
doaj   +1 more source

Prospective validation of podoplanin expression as a diagnostic biomarker of acute promyelocytic leukemia

open access: yesCytometry Part B: Clinical Cytometry, Volume 110, Issue 2, Page 128-133, March 2026.
Abstract Acute promyelocytic leukemia (APL) is a medical emergency that needs immediate diagnosis and treatment. Podoplanin, a transmembrane glycoprotein that binds CLEC‐2 on platelets, was recently demonstrated to be abnormally expressed in leukemic blasts in APL, as opposed to other forms of AML, in a study using thawed primary cells.
Camilla Maria de Alencar Saraiva   +7 more
wiley   +1 more source

Resveratrol Activates Antioxidant Protective Mechanisms in Cellular Models of Alzheimer’s Disease Inflammation

open access: yesAntioxidants
Resveratrol is a natural phenolic compound with known benefits against neurodegeneration. We analyzed in vitro the protective mechanisms of resveratrol against the proinflammatory monomeric C-reactive protein (mCRP).
Clara Bartra   +8 more
doaj   +1 more source

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