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Abstract 755: Antagonistic effect of M-MDSC and N-MDSC during astrocytoma progression
Cancer Research, 2016Abstract The traditional dogma holds that tumor size has a positive correlation with tumor progression. However, on murine orthotopical astrocytoma model ALTS1C1, we found that the tumor growth is not a linear function instead a shrinkage and regrowth wave was noticed.
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Mission Data Storage Consolidation (MDSC)
SpaceOps 2002 Conference, 2002This paper describes a storage related project undertaken on the Consolidated Space Operations Contract (CSOC) by Lockheed Martin Space Operations (LMSO). The project, Mission Data Storage Consolidation (MDSC), was defined with the intent of enabling NASA’s Johnson Space Center (JSC) to reduce storage costs in ground systems and related support ...
Ray Hunnicutt, David Garza
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Ex Vivo MDSC Differentiation Models
2016The development of adequate ex vivo cell differentiation models is the key for the study of cell ontology and functions. For example, since ex vivo differentiation systems for conventional myeloid dendritic cells (DCs) were developed, research in these important regulators of immunity was significantly increased.
David Escors, Grazyna Kochan
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Rapid Isolation of untouched mouse MDSCs
The Journal of Immunology, 2019Abstract Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of cells that regulate immune responses in cancer, chronic infections and inflammatory conditions. In an individual with a tumor burden, MDSCs accumulate in peripheral lymphoid organs and within the tumor microenvironment.
Frann Antignano +7 more
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Pak2 Regulates MDSC Development and Function
Blood, 2016Abstract Myeloid derived suppressor cells (MDSCs) are a heterogeneous cell population at various stages of differentiation that can increase under various pathologic conditions such as cancer, infection or inflammation, displaying suppressive function.
Yi Zeng +5 more
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MDSC: Myeloid-Derived Suppressor Cells
2016Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of immature myeloid cells whose numbers are increased in states of cancer, inflammation, or infection. MDSC are reported to be induced by tumor-produced growth factors in cancer-bearing hosts. Mechanisms of immune suppression by MDSC include production of arginase-1, reactive oxygen
Masahiko Shibata +2 more
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LXR Agonism Depletes MDSCs to Promote Antitumor Immunity
Cancer Discovery, 2018Abstract LXR activation reduces immunosuppressive MDSCs to activate antitumor cytotoxic T cells.
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Notch-mediated lactate metabolism regulates MDSC development through the Hes1/MCT2/c-Jun axis
Cell Reports, 2022Jun-Long Zhao, Yu-Chen Ye, Liang Wang
exaly
Myeloid-derived suppressor cells (MDSC): When good intentions go awry
Cellular Immunology, 2021Maria Dulfary Sanchez-Pino, Matthew Dean
exaly