Results 251 to 260 of about 51,191 (308)

The dynamic myeloid-enriched microenvironment of glioblastoma: a major challenge to immunotherapy efficacy. [PDF]

Front Immunol
Lamorlette C, Boura C, Pinel S, Bensoussan D, Dotti G, Alanio C, Reppel L.   +6 more
europepmc   +1 more source

Isocitrate Dehydrogenase Mutations in Cancer: From Bench to Bedside Applications

MedComm, Volume 7, Issue 5, May 2026.
Mutant isocitrate dehydrogenase affects multiple cancer types. Alterations in IDH1 and IDH2 result in abnormal enzyme activity, leading to the overproduction of D‐2‐hydroxyglutarate (D‐2HG). This metabolite disrupts cellular metabolism and epigenetic regulation, driving cancer initiation, progression, and metastasis.
Yuhan Fang, Xiaoqing Wang, Kai Luo, Tikam Chand Dakal, He Bai, Caiming Xu, Guixin Zhang   +6 more
wiley   +1 more source

RNA Modifications: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 5, May 2026.
Types of RNA modification. We have summarized the currently common types of RNA modifications, including ac4C, m6A, m1A, m5C, m3C, m7G, and ψ, and visually characterized their features through structural formulas. The characteristic structures are marked with a background color different from the background color.
Shiyu Xiao, Tingwen Xiang, Chuan Yang, Xiaohua Wang, Gang Huang, Fei Luo, Zhao Xie, Yueqi Chen   +7 more
wiley   +1 more source

Causal Exposures of Immune Cells in Neuromyelitis Optica Spectrum Disorders: A Mendelian Randomization Study and Flow Cytometry Analysis. [PDF]

Brain Behav
Ren J, Wang J, Niu Z, Guo J, Zhang N, Hao H, Gao F, Liu R, Wang Z.   +8 more
europepmc   +1 more source

Innate Lymphoid Cells in Tissue Homeostasis and Diseases

MedComm, Volume 7, Issue 5, May 2026.
Innate lymphoid cells (ILCs) are a heterogeneous group of immune cells with phenotypic and functional plasticity. ILCs dynamically regulate various immune cell types and play a crucial role in the pathophysiological processes of specific organs during sepsis. Targeting ILCs is a promising strategy for treating sepsis.
Zhenzhen Zhan, Heyang Sun, Chenning Li, Qianya Hong, Shuainan Zhu, Ying Yu, Hao Zhang, Kefang Guo   +7 more
wiley   +1 more source

Pan-Cancer Single-Cell RNA Sequencing Analysis Refines Multi-Origin Monocyte and Macrophage Lineages. [PDF]

Cancer Immunol Res
Nguyen TDT, Lee AJ, Park HJ, Shah N, Mandzhieva B, Lee DS, Jung I, Park WY.   +7 more
europepmc   +1 more source

Cannabidiol suppresses emergency MDSCs generation by disturbing EEF1B2-mediated C/EBP<i>β</i> protein synthesis in colorectal adenomas. [PDF]

J Immunother Cancer
Pan J, Zhao L, Du H, Zhu Y, Sun X, Xu Q, Cheng H, Chen H, Sun Y.   +8 more
europepmc   +1 more source

Cyclophosphamide-Mediated Induction of Myeloid-Derived Suppressor Cells In Vivo: Kinetics of Accumulation, Immune Profile, and Immunomodulation by Oleanane-Type Triterpenoids. [PDF]

Int J Mol Sci
Awad MS, Sen'kova AV, Markov AV, Salomatina OV, Zenkova MA, Markov OV.   +5 more
europepmc   +1 more source

Defining the marker and developmental trajectory of myeloid-derived suppressor cells in aging by single-cell transcriptomics. [PDF]

NPJ Aging
Su Y, Wu R, Ai H, Zhong Z, Zou L, Wang Z, Tu K, Tang L, Gao J, Huang Y, Liao C, Zeng G, Zhang H, Jin J, Zhu S.   +14 more
europepmc   +1 more source

Differential sensitivity of leukocyte populations to <i>Staphylococcus aureus</i> biofilm. [PDF]

Infect Immun
Brandquist ND, Kielian T.
europepmc   +1 more source