Results 281 to 290 of about 51,191 (308)

MDSC: Myeloid-Derived Suppressor Cells

2016
Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of immature myeloid cells whose numbers are increased in states of cancer, inflammation, or infection. MDSC are reported to be induced by tumor-produced growth factors in cancer-bearing hosts. Mechanisms of immune suppression by MDSC include production of arginase-1, reactive oxygen
Masahiko Shibata, Kenji Gonda, Seiichi Takenoshita   +2 more
openaire   +1 more source

LXR Agonism Depletes MDSCs to Promote Antitumor Immunity

Cancer Discovery, 2018
Abstract LXR activation reduces immunosuppressive MDSCs to activate antitumor cytotoxic T cells.
openaire   +2 more sources

Autophagy & MDSCs

Nature Immunology, 2018
openaire   +2 more sources

PMN-MDSCs modulated by CCL20 from cancer cells promoted breast cancer cell stemness through CXCL2-CXCR2 pathway

Signal Transduction and Targeted Therapy, 2023
Juchuanli Tu, XUEYAN HE, Suling Liu
exaly  

Regulating MDSC recruitment

Nature Reviews Immunology, 2008
openaire   +1 more source

Multifunctional Nanodrug Mediates Synergistic Photodynamic Therapy and MDSCs‐Targeting Immunotherapy of Colon Cancer

Advanced Science, 2021
Jun Shao, Xintao Shuai, Bo Wei
exaly  

MDSCs in liver cancer: A critical tumor-promoting player and a potential therapeutic target

Cellular Immunology, 2021
Chi Ma, Qianfei Zhang, Tim F Greten
exaly  

New Insights into the Multifaceted Role of Myeloid-Derived Suppressor Cells (MDSCs) in High-Grade Gliomas: From Metabolic Reprograming, Immunosuppression, and Therapeutic Resistance to Current Strategies for Targeting MDSCs

Cells, 2021
Senthilnath Lakshmanachetty, Joselyn Cruz-Cruz, Siddhartha S Mitra   +2 more
exaly  

Optimized CAR-T therapy based on spatiotemporal changes and chemotactic mechanisms of MDSCs induced by hypofractionated radiotherapy

Molecular Therapy, 2023
Benxia Zhang, Yongsheng Wang
exaly  

Human MDSCs

2016
openaire   +1 more source