Results 121 to 130 of about 19,782 (285)

Metabolic and Microvascular Risk Factors Associated With Brain Health in Type 1 Diabetes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We examined relationships between metabolic factors, microvascular complications, and brain health in adults with type 1 diabetes. Fifty‐one adults were assessed for metabolic risk factors, microvascular complications, and cognitive function, with a subset completing brain MRI.
Jihyun Park   +7 more
wiley   +1 more source

“The meaningfulness of work can be summed up by the fact that this work is what I am meant to do.” : educational scientists’ experiences of the meaningfulness of work

open access: yes, 2023
Tämän pro gradu -tutkielman tarkoituksena on tarkastella kasvatustieteilijöiden kokemuksia työn merkityksellisyydestä. Merkityksellisen työn tutkimus on lisääntynyt huomattavasti ja sen merkitys on nousemassa yhä suurempaan rooliin työelämän muutoksen ...
Vanhanen, Sanni
core  

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller   +14 more
wiley   +1 more source

Impact of Green HRM implementation on organizational sustainability in IT sector: A mediation analysis

open access: yesSustainable Futures
As organizations increasingly seek sustainable practices to address environmental challenges, Green human resource management (Green HRM) emerges as a critical strategy for integrating environmental management into HR practices.
Rakesh Naik Vadithe   +2 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Work engagement, psychological meaningfulness and psychological safety : a leadership perspective

open access: yes, 2016
M.Phil.Abstract: Effective leadership is vital for any organisation as a leader has the power and ability to mould the culture within an organisation. Theory has linked the level of engagement, meaningfulness and psychological safety of employees to the ...
Dicks, Genevieve
core  

The effect of occupational meaningfulness on occupational commitment

open access: yesInternational Journal of Psychological Research, 2014
Existing research lacks a scholarly consensus on how to define and validly measure ‘meaningful work’ (e.g., Rosso, Dekas & Wrzesniewski, 2010). The following correlational study highlights the value of investigating meaningfulness in the context of ...
Itai Ivtzan   +2 more
doaj  

The Gender Gap in Meaningful Work

open access: yesManagement Science
An understanding of differences in nonmonetary work conditions is fundamental for a complete characterization of individuals’ well-being at work. Thus, to fully characterize gender inequalities in the labor market, scholars have begun to explore gender differences in nonmonetary work conditions.
Vanessa C. Burbano   +3 more
openaire   +5 more sources

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe   +7 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

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