Results 91 to 100 of about 10,274 (232)

Effect of matrix heterogeneity on cell mechanosensing

, 2021
Maria Proestaki, Brian Burkel, Emmett E. Galles, Suzanne M. Ponik, Jacob Notbohm   +4 more
openalex   +2 more sources

Mechanosensing by Vascular Endothelium

Annual Review of Physiology
Mechanical forces influence different cell types in our bodies. Among the earliest forces experienced in mammals is blood movement in the vascular system. Blood flow starts at the embryonic stage and ceases when the heart stops. Blood flow exposes endothelial cells (ECs) that line all blood vessels to hemodynamic forces.
Xin Rui, Lim, Osama F, Harraz
openaire   +2 more sources

Inflammation and mechanical force‐induced bone remodeling

Periodontology 2000, EarlyView.
Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon, Xin Huang, Leticia Rojas Cortez, Puttipong Sripinun, Jung‐me Lee, Julie J. Hong, Dana T. Graves   +6 more
wiley   +1 more source

α-catenin, vinculin, and F-actin in strengthening E-cadherin cell–cell adhesions and mechanosensing [PDF]

, 2013
Sylvie Dufour, René‐Marc Mège, Jean Paul Thiery   +2 more
openalex   +1 more source

TrpA1 is a shear stress mechanosensing channel regulating intestinal homeostasis in Drosophila [PDF]

, 2022
Jiaxin Gong, Niraj K. Nirala, Jiazhang Chen, Fei Wang, Pengyu Gu, Qi Wen, Y. Tony Ip, Yang Xiang   +7 more
openalex   +1 more source

Matrix Viscoelasticity: The Overlooked Architect of Solid Tumour Evolution

Organ Medicine, EarlyView.
Ruixi Huang, Yupeng Guan
wiley   +1 more source

Advances in cardiac devices and bioelectronics augmented with artificial intelligence

The Journal of Physiology, EarlyView.
Abstract figure legend Interfaces between the human heart, diagnostic bioelectronics, artificial intelligence, and clinical care. From left to right: Human heart and biosensor interface; representative waveforms of common diagnostic bioelectronic sensing modalities.
Charles Stark, Eric Rytkin, Andrei Alexandru Mircea, Igor R. Efimov   +3 more
wiley   +1 more source

Mathematical modeling of mechanosensitive reversal control in Myxococcus xanthus

Frontiers in Microbiology
Adjusting motility patterns according to environmental cues is important for bacterial survival. Myxococcus xanthus, a bacterium moving on surfaces by gliding and twitching mechanisms, modulates the reversal frequency of its front-back polarity in ...
Yirui Chen, Yirui Chen, Elias J. Topo, Beiyan Nan, Jing Chen, Jing Chen, Jing Chen   +6 more
doaj   +1 more source

Generation of contractile actomyosin bundles depends on mechanosensitive actin filament assembly and disassembly

eLife, 2015
Adhesion and morphogenesis of many non-muscle cells are guided by contractile actomyosin bundles called ventral stress fibers. While it is well established that stress fibers are mechanosensitive structures, physical mechanisms by which they assemble ...
Sari Tojkander, Gergana Gateva, Amjad Husain, Ramaswamy Krishnan, Pekka Lappalainen   +4 more
doaj   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, Volume 16, Issue 3, Page 496-502, March 2026.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source