Results 81 to 90 of about 7,197,670 (160)

Analysis of the median effective dose and adverse effects of methylene blue combined with ropivacaine for fascia iliaca compartment block in postoperative analgesia in elderly patients undergoing hip arthroplasty

open access: yesShiyong laonian yixue
[Objective] To determine the median effective dose (ED50) and 95% effective dose (ED95) of methylene blue as an adjuvant to ropivacaine in elderly patients undergoing fascia iliaca compartment block for postoperative 24-hour effective analgesia without ...
ZHANG Yang, YANG Shun, LU Ziru, SHA Lili
doaj   +1 more source

A phototaxis assay to measure sublethal effects of pesticides on bees

open access: yesScientific Reports
In agricultural areas, bees are pervasively exposed to pesticides at sublethal concentrations. Methods to establish whether these concentrations may cause negative effects are needed to assess the potential hazards of field-realistic levels of exposure ...
Gonzalo Sancho   +5 more
doaj   +1 more source

Optimal designs for dose-response models with restricted design spaces [PDF]

open access: yes
In dose response studies, the dose range is often restricted due to concerns over drug toxicity and/or efficacy. We present restricted and unrestricted interval locally optimal designs with respect to a very general class of optimality criteria for ...
Zhu, Wei   +2 more
core  

Effective doses of nalmefene for prevention of sufentanil-induced cough during induction of general anesthesia in children

open access: yesZhongguo linchuang yanjiu
Objective To determine the median effective dose(ED50)and 95% effective dose(ED95)of namefene hydrochloride in inhibiting sufentanil-induced cough(SIC)during induction of general anesthesia in children.Methods Thirty-five children[aged 1-6 years, 29 ...
XU Zhijun, JIA Jian
doaj   +1 more source

The Impact of Fentanyl on the Effective Dose of Remimazolam-Induced Sedation in Elderly Female Patients: An Up-and-Down Sequential Allocation Trial [PDF]

open access: yes
Xiao-Dong Huang,1,* Jia-Bao Chen,2,* Xiao-Yun Dong,1 Wei-Long Wang,1 Jin Zhou,1 Zhen-Feng Zhou1 1Department of Anesthesiology, Hangzhou Women’s Hospital (Hangzhou Maternity and Child Health Care Hospital, Hangzhou First People’s Hospital ...
Chen JB   +5 more
core  

Interval estimation of the median effective dose for a logistic dose-response curve

open access: yes
In 1986, Williams showed how, assuming a logistic dose-response curve, one can construct a confidence interval for the median effective dose from the asymptotic likelihood ratio test.
John Dearden   +3 more
core   +1 more source

Cumulative effective radiation dose in 54 SOT recipients over a median of 6 years post-transplant.

open access: yes, 2017
Solid red circles represent patients who received an effective radiation dose > 100 mSV, a threshold associated with increased cancer risk. Horizontal lines represent the median effective dose in each subgroup.
Michael Hawkes (234024)   +6 more
core   +1 more source

ED50 of remimazolam combined with different doses butorphanol for first trimester artificial abortion

open access: yesFrontiers in Medicine
IntroductionRemimazolam (RMZ) is a novel intravenous sedative drug of ultra-short benzodiazepine. The optimal dose of RMZ plus butorphanol for sedation during first trimester artificial abortion is unknown.
Jinming Chen   +5 more
doaj   +1 more source

ED50 of hydromorphone suppressing body movement in artificial abortion: A dose-finding study

open access: yesPakistan Journal of Pharmaceutical Sciences
The present study attempted to investigate the median effective dose (ED50) of hydromorphone on suppressing of body movement in artificial abortion. A total of 23 female patients were assigned into the study using the up-and-down method. The usage amount
Lijun Peng, Lingli Liu
doaj   +1 more source

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