Results 51 to 60 of about 47,257 (190)

Studies on the megakaryocytes, platelets separation and degeneration [PDF]

, 1958
From these findings, we confirmed that the tongue-like process formations of the cells which are still believed as the platelets formation by many investigators, would be nothing but the presentation of the cell degeneration and platelets are separated ...
Hiraki, Kiyoshi, Ogawara, Kenjiro, Sunami, Hiroshi   +2 more
core   +1 more source

Gfi1b controls integrin signaling-dependent cytoskeleton dynamics and organization in megakaryocytes

Haematologica, 2017
Mutations in GFI1B are associated with inherited bleeding disorders called GFI1B-related thrombocytopenias. We show here that mice with a megakaryocyte-specific Gfi1b deletion exhibit a macrothrombocytopenic phenotype along a megakaryocytic dysplasia ...
Hugues Beauchemin, Peiman Shooshtarizadeh, Charles Vadnais, Lothar Vassen, Yves D Pastore, Tarik Möröy   +5 more
doaj   +1 more source

Extra medullar Granulocytic sarcoma: a case report of an exceptional localization [PDF]

, 2020
Granulocytic sarcoma is a rare type of tumor composed of extramedullary immature cells. The breast location is very rare; it accounts for less than 8% of cases.
Khaled, Rahal, Malek, Bouhani, Olfa, Adouni, Olfa, Jaidane, Riadh, Chargui, Saida, Sakhri   +5 more
core   +2 more sources

Tetraspanin CD9 participates in dysmegakaryopoiesis and stromal interactions in primary myelofibrosis

Haematologica, 2015
Primary myelofibrosis is characterized by clonal myeloproliferation, dysmegakaryopoiesis, extramedullary hematopoiesis associated with myelofibrosis and altered stroma in the bone marrow and spleen.
Christophe Desterke, Christophe Martinaud, Bernadette Guerton, Lisa Pieri, Costanza Bogani, Denis Clay, Frederic Torossian, Jean-Jacques Lataillade, Hans C. Hasselbach, Heinz Gisslinger, Jean-Loup Demory, Brigitte Dupriez, Claude Boucheix, Eric Rubinstein, Sophie Amsellem, Alessandro M. Vannucchi, Marie-Caroline Le Bousse-Kerdilès   +16 more
doaj   +1 more source

Myelodysplasia in a psoriasis patient receiving etanercept : Cause or coincidence? [PDF]

, 2018
Peer reviewedFinal Accepted ...
Ayoub, Othman Hadi, Dawoud, Dalia M, Dawoud, Noha Mohammed, Essa, Enas Said   +3 more
core   +3 more sources

Modified application of Kawamoto’s film method for super‐resolution imaging of megakaryocytes in undecalcified bone marrow

Research and Practice in Thrombosis and Haemostasis, 2020
Background Super‐resolution microscopy has enabled high‐resolution imaging of the actin cytoskeleton in megakaryocytes and platelets. These technologies have extended our knowledge of thrombopoiesis and platelet spreading using megakaryocytes and ...
Yosuke Morodomi, Sachiko Kanaji, Eric Won, Tadafumi Kawamoto, Taisuke Kanaji   +4 more
doaj   +1 more source

HDAC inhibition is associated to valproic acid induction of early megakaryocytic markers [PDF]

, 2006
Valproic acid (VPA), a histone deacetylase inhibitor, causes differentiation in different cell lines and in a cell-specific manner; yet, its effect on megakaryocytic (MK) differentiation has not been studied.
Ciccarelli, Carmela, Giampaolo, Adele, Giampiero, Macioce, Hassan, Hamisa J, Marampon, Francesco, Mattia, Gianfranco, Milazzo, Luisa, Pascuccio, Massimiliano, Vulcano, Francesca, Zani, Bianca M   +9 more
core  

Mutated JAK2 signal transduction in human induced pluripotent stem cell (iPSC)-derived megakaryocytes

Platelets, 2022
Janus kinase 2 (JAK2) gene mutations are the main drivers for polycythemia vera (PV) and essential thrombocythemia (ET). The mechanisms of single altered gene causing two different diseases are unclear.
Jaturawat Pawinwongchai, Panchalee Jangprasert, Nungruthai Nilsri, Nipan Israsena, Ponlapat Rojnuckarin   +4 more
doaj   +1 more source

Role of platelets and megakaryocytes in adaptive immunity

Platelets, 2021
The immune system is comprised of two principal interconnected components called innate and adaptive immunity. While the innate immune system mounts a nonspecific response that provides protection against the spread of foreign pathogens, the adaptive ...
Genevieve Marcoux, Audrée Laroche, Jenifer Espinoza Romero, Eric Boilard   +3 more
doaj   +1 more source

P38 Kinase, SGK1 and NF-κB Dependent Up-Regulation of Na+/Ca2+ Exchanger Expression and Activity Following TGFß1 Treatment of Megakaryocytes [PDF]

, 2017
Background: TGFβ1, a decisive regulator of megakaryocyte maturation and platelet formation, has previously been shown to up-regulate both, store operated Ca2+ entry (SOCE) and Ca2+ extrusion by Na+/Ca2+ exchange.
Al-Maghout, Tamer, Gawaz, Meinrad, Gutti, Ravi, Hosseinzadeh, Zohreh, Lang, Florian, Laufer, Stefan, Pelzl, Lisann, Pieske, Burkert, Sahu, Itishri, Sukkar, Basnna, Voelkl, Jakob   +10 more
core   +2 more sources