Results 81 to 90 of about 47,257 (190)

BMQ [PDF]

open access: yes, 1963
BMQ: Boston Medical Quarterly was published from 1950-1966 by the Boston University School of Medicine and the Massachusetts Memorial ...
Antuna, Juan   +25 more
core  

Megakaryocytes Enhance Mesenchymal Stromal Cells Proliferation and Inhibit Differentiation [PDF]

open access: yes, 2017
Megakaryocytes (MKs) can induce proliferation of calvarial osteoblasts [Ciovacco et al., 2009], but this same phenomenon has not been reported for bone marrow stromal populations from long bones.
Alvarez, Marta B.   +7 more
core   +2 more sources

PERT: A Method for Expression Deconvolution of Human Blood Samples from Varied Microenvironmental and Developmental Conditions [PDF]

open access: yes, 2012
The cellular composition of heterogeneous samples can be predicted using an expression deconvolution algorithm to decompose their gene expression profiles based on pre-defined, reference gene expression profiles of the constituent populations in these ...
A Posekany   +29 more
core   +3 more sources

MicroRNA function in megakaryocytes

open access: yesPlatelets, 2018
Megakaryocytes (MKs), the largest cells in the bone marrow, are generated from hematopoietic stem cells (HSCs) in a sequential process called megakaryocytopoiesis in which HSCs undergo MK-progenitor (MP) commitment and maturation to terminally differentiated MK.
Sanjeev Raghuwanshi   +9 more
openaire   +3 more sources

Modulation of interferon-[alpha] secretion by activated platelets in systemic lupus erythematosus. [PDF]

open access: yes, 2008
Type I interferons play a key role in systemic lupus erythematosus (SLE) pathogenesis as an "IFN signature" is found in the majority of patients with active SLE.
Bernard Weill   +8 more
core   +1 more source

GATA-1 deficiency rescues trabecular but not cortical bone in OPG deficient mice [PDF]

open access: yes, 2014
GATA-1(low/low) mice have an increase in megakaryocytes (MKs) and trabecular bone. The latter is thought to result from MKs directly stimulating osteoblastic bone formation while simultaneously inhibiting osteoclastogenesis.
Cheng, Ying-Hua   +6 more
core   +1 more source

A novel method for automated assessment of megakaryocyte differentiation and proplatelet formation

open access: yesPlatelets, 2018
Transfusion of platelet concentrates represents an important treatment for various bleeding complications. However, the short half-life and frequent contaminations with bacteria restrict the availability of platelet concentrates and raise a clear demand ...
M. Salzmann   +9 more
doaj   +1 more source

Megakaryocytes [PDF]

open access: yesArteriosclerosis, Thrombosis, and Vascular Biology, 2020
Philip J. Crispin, Samantha J. Montague
openaire   +2 more sources

Survival Motor Neuron (SMN) protein is required for normal mouse liver development [PDF]

open access: yes, 2016
Spinal Muscular Atrophy (SMA) is caused by mutation or deletion of the survival motor neuron 1 (SMN1) gene. Decreased levels of, cell-ubiquitous, SMN protein is associated with a range of systemic pathologies reported in severe patients.
Francesco, M   +6 more
core  

Engineered and hybrid human megakaryocytic extracellular vesicles for targeted non-viral cargo delivery to hematopoietic (blood) stem and progenitor cells

open access: yesFrontiers in Bioengineering and Biotechnology
Native and engineered extracellular vesicles generated from human megakaryocytes (huMkEVs) or from the human megakaryocytic cell line CHRF (CHEVs) interact with tropism delivering their cargo to both human and murine hematopoietic stem and progenitor ...
Samik Das   +6 more
doaj   +1 more source

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