Results 81 to 90 of about 47,257 (190)
BMQ: Boston Medical Quarterly was published from 1950-1966 by the Boston University School of Medicine and the Massachusetts Memorial ...
Antuna, Juan +25 more
core
Megakaryocytes Enhance Mesenchymal Stromal Cells Proliferation and Inhibit Differentiation [PDF]
Megakaryocytes (MKs) can induce proliferation of calvarial osteoblasts [Ciovacco et al., 2009], but this same phenomenon has not been reported for bone marrow stromal populations from long bones.
Alvarez, Marta B. +7 more
core +2 more sources
PERT: A Method for Expression Deconvolution of Human Blood Samples from Varied Microenvironmental and Developmental Conditions [PDF]
The cellular composition of heterogeneous samples can be predicted using an expression deconvolution algorithm to decompose their gene expression profiles based on pre-defined, reference gene expression profiles of the constituent populations in these ...
A Posekany +29 more
core +3 more sources
MicroRNA function in megakaryocytes
Megakaryocytes (MKs), the largest cells in the bone marrow, are generated from hematopoietic stem cells (HSCs) in a sequential process called megakaryocytopoiesis in which HSCs undergo MK-progenitor (MP) commitment and maturation to terminally differentiated MK.
Sanjeev Raghuwanshi +9 more
openaire +3 more sources
Modulation of interferon-[alpha] secretion by activated platelets in systemic lupus erythematosus. [PDF]
Type I interferons play a key role in systemic lupus erythematosus (SLE) pathogenesis as an "IFN signature" is found in the majority of patients with active SLE.
Bernard Weill +8 more
core +1 more source
GATA-1 deficiency rescues trabecular but not cortical bone in OPG deficient mice [PDF]
GATA-1(low/low) mice have an increase in megakaryocytes (MKs) and trabecular bone. The latter is thought to result from MKs directly stimulating osteoblastic bone formation while simultaneously inhibiting osteoclastogenesis.
Cheng, Ying-Hua +6 more
core +1 more source
A novel method for automated assessment of megakaryocyte differentiation and proplatelet formation
Transfusion of platelet concentrates represents an important treatment for various bleeding complications. However, the short half-life and frequent contaminations with bacteria restrict the availability of platelet concentrates and raise a clear demand ...
M. Salzmann +9 more
doaj +1 more source
Philip J. Crispin, Samantha J. Montague
openaire +2 more sources
Survival Motor Neuron (SMN) protein is required for normal mouse liver development [PDF]
Spinal Muscular Atrophy (SMA) is caused by mutation or deletion of the survival motor neuron 1 (SMN1) gene. Decreased levels of, cell-ubiquitous, SMN protein is associated with a range of systemic pathologies reported in severe patients.
Francesco, M +6 more
core
Native and engineered extracellular vesicles generated from human megakaryocytes (huMkEVs) or from the human megakaryocytic cell line CHRF (CHEVs) interact with tropism delivering their cargo to both human and murine hematopoietic stem and progenitor ...
Samik Das +6 more
doaj +1 more source

