Microbiota-Inflammation Crosstalk in Myeloproliferative Neoplasms: MPN-Specific Human Data, Mechanistic Plausibility and Translational Priorities. [PDF]
Țîrlea LG, Lipan L, Tănase AD.
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Do Platelets Explain Why GnRH Antagonists Are Potentially Safer From a Cardiovascular Perspective? [PDF]
Deng Y, Wang Y, Cheng L.
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Case Report: A rare case of primary graft failure after autologous stem cell transplant for mantle cell lymphoma rescued with darbepoetin, eltrombopag, and cyclosporine. [PDF]
Ly SH +6 more
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An unconquered challenge in MDS: review of pathophysiology, clinical manifestations, and management options of MDS with thrombocytopenia. [PDF]
Chen X, Shukla M, Choi JH.
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Secondary Evans Syndrome Associated with Localized Clear Cell Renal Cell Carcinoma: A Case Report and Brief Literature Review. [PDF]
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Cytokine control of megakaryopoiesis
Growth Factors, 2018Platelets are anuclear blood cells required for haemostasis and are implicated in other processes including inflammation and metastasis. Platelets are produced by megakaryocytes, specialized cells that are themselves generated by a process of controlled ...
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DNA damage repair in megakaryopoiesis: molecular and clinical aspects
Expert Review of HematologyIntroduction Endogenous DNA damage is a significant factor in the damage of hematopoietic cells. Megakaryopoiesis is one of the pathways of hematopoiesis that ends with the production of platelets and plays the most crucial role in hemostasis.
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Purpose of review Megakaryocytes are large, polyploid cells that produce platelets and originate from hematopoietic stem cells (HSCs) in the bone marrow.
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