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Single-cell profiling of ANKRD26 thrombocytopenia reveals progenitor expansion and polyploid apoptosis via JUNB-p21.

open access: yesBlood
Chen L   +24 more
europepmc   +1 more source
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Cytokine control of megakaryopoiesis

Growth Factors, 2018
Platelets are anuclear blood cells required for haemostasis and are implicated in other processes including inflammation and metastasis. Platelets are produced by megakaryocytes, specialized cells that are themselves generated by a process of controlled ...
Kira Behrens, Warren S Alexander
exaly   +4 more sources

DNA damage repair in megakaryopoiesis: molecular and clinical aspects

Expert Review of Hematology
Introduction Endogenous DNA damage is a significant factor in the damage of hematopoietic cells. Megakaryopoiesis is one of the pathways of hematopoiesis that ends with the production of platelets and plays the most crucial role in hemostasis.
Najmaldin Saki, Mojtaba Aghaei
exaly   +2 more sources

Direct megakaryopoiesis

Current Opinion in Hematology
Purpose of review Megakaryocytes are large, polyploid cells that produce platelets and originate from hematopoietic stem cells (HSCs) in the bone marrow.
H. Snoeck
semanticscholar   +3 more sources

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