Results 111 to 120 of about 123,035 (391)

Exosomal miR-222-3p derived from dermal papilla cells inhibits melanogenesis in melanocytes by targeting SOX10 in rabbits [PDF]

Animal Bioscience
Objective Dermal papilla cells (DPCs) play a pivotal role in hair follicle development and can modulate melanogenesis in melanocytes (MCs) through their microenvironment.
Yang Chen, Tingting Lu, Yingying Dai, Yu Xue, Bohao Zhao, Xinsheng Wu   +5 more
doaj   +1 more source

The Influence of Drosophila Spire and Myosin V During Mid‐Oogenesis Is Independent of Their Direct Interaction

Cytoskeleton, EarlyView.
ABSTRACT Cooperativity between cytoskeletal proteins is crucial for spatiotemporal coordination in biological processes, like oogenesis. In mammalian and Drosophila oogenesis, proper assembly and function of actin networks require coordination between actin assembly factors Spire and formins, as well as actin‐associated proteins like myosins and Rab ...
Joseph Y. Ong, Hannah M. Bailey, Emma Carley, Michelle Panzica, Merin Rixen, Neil Billington, Rong Liu, Margot E. Quinlan   +7 more
wiley   +1 more source

Harnessing autophagy to overcome mitogen‐activated protein kinase kinase inhibitor‐induced resistance in metastatic melanoma [PDF]

, 2019
Background Patients with malignant melanoma often relapse after treatment with BRAF and/or mitogen‐activated protein kinase kinase (MEK) inhibitors (MEKi) owing to development of drug resistance.
Alexander, M., Chaudhry, B., Edwards, N., Hill, David, Lovat, P.E., Plummer, R., Verykiou, S.   +6 more
core   +1 more source

The association between neural crest‐derived glia and melanocyte lineages throughout development and disease

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient cell population that emerges from the dorsal neural tube during neurulation and migrates extensively throughout the embryo. Among their diverse derivatives, glial cells (such as Schwann and satellite ganglionic cells) and melanocytes represent two major lineages. In vitro studies suggested they share a common
Chaya Kalcheim
wiley   +1 more source

Melanoma: Genetic Abnormalities, Tumor Progression, Clonal Evolution and Tumor Initiating Cells

Medical Sciences, 2017
Melanoma is an aggressive neoplasia issued from the malignant transformation of melanocytes, the pigment-generating cells of the skin. It is responsible for about 75% of deaths due to skin cancers.
Ugo Testa, Germana Castelli, Elvira Pelosi   +2 more
doaj   +1 more source

Protein Energy Malnutrition: Opportunities for Cold Plasma Technologies

Food Frontiers, EarlyView.
Protein energy malnutrition (PEM) is a major global health concern driven by biological, environmental, and nutritional factors, including gut microbiota imbalance and low protein intake. Cold atmospheric plasma technologies offer promising, sustainable solutions by improving food security, enhancing protein quality and absorption, and modulating gut ...
Karthika Prasad, Syamlal Sasi, Nina Recek, Janith Weerasinghe, Elena P. Ivanova, Igor Levchenko, Katia Alexander   +6 more
wiley   +1 more source

Development and in vitro evaluation of chitosan nanoparticles encapsulating Phoenix dactylifera L. (Ajwah) seed extract with supporting in silico molecular docking analysis

Food Biomacromolecules, EarlyView.
Abstract This research describes the engineering of chitosan nanoparticles (CS NPs) via ionic gelation to I'm double or somethingencapsulate Ajwah seed extract (ASE), repurposing a plant waste product for its documented antioxidant and anticancer potential.
Jailan E. Elhalawani, Amro Shetta, Wael Mamdouh   +2 more
wiley   +1 more source

Role of microRNA508-3p in melanogenesis by targeting microphthalmia transcription factor in melanocytes of alpaca

Animal, 2017
It has been demonstrated that microRNAs (miRNAs) play important roles in the control of melanogenesis and hair color in mammals. By comparing miRNA expression profiles between brown and white alpaca skin, we previously identified miR508-3p as a ...
J. Zhang, Y. Liu, Z. Zhu, S. Yang, K. Ji, S. Hu, X. Liu, J. Yao, R. Fan, C. Dong   +9 more
doaj   +1 more source

DHODH modulates transcriptional elongation in the neural crest and melanoma [PDF]

, 2011
Melanoma is a tumour of transformed melanocytes, which are originally derived from the embryonic neural crest. It is unknown to what extent the programs that regulate neural crest development interact with mutations in the BRAF oncogene, which is the ...
AD Boiko, AL Rubinstein, AV Molofsky, BR Keegan, Charles Kaufman, Charles Y. Lin, Christopher J. Burke, CT Nguyen, D Mueller, Donna Neuberg, Erin Langdon, Frank Chen, GN Wheeler, Grant N. Wheeler, H Davies, Hannah K. Long, J Tsai, Jack Mosher, JE McLean, Jennifer Cech, K Krishnan, KT Flaherty, Leonard I. Zon, LM Graves, M Löffler, Martin Kramer, Matthew L. Tomlinson, MH Schiff, MJ Kaplan, PB Rahl, Peter B. Rahl, R Luo, Richard A. Young, Richard Mark White, RM Bakos, S Bixby, S Guo, SB Ng, Scott Granter, Sean Morrison, SK Hong, Sumon Datta, Sutheera Ratanasirintrawoot, T Aoki, T Wada, X Bai, Y Chen   +46 more
core   +1 more source

Youngest known case of a pancreatic perivascular epithelioid cell tumor

JPGN Reports, EarlyView.
Abstract Perivascular epithelioid cell tumors (PEComas) are a rare type of mesenchymal tumor that can arise in any part of the body. As of 2024, 37 cases of pancreatic PEComas had been reported in the literature with patients ranging in age from 17 to 74 years old.
Laura Gilligan, Wesley C. Judy, Bryan Clary, Timothy Fairbanks, Denise Malicki, Tom K. Lin   +5 more
wiley   +1 more source