Results 111 to 120 of about 85,786 (342)

Diffuse Melanosis Cutis Under Immuno‐ and Targeted Therapy

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT In patients with highly advanced melanoma, rarely a diffuse melanosis cutis (DMC) can be noticed. Even though the condition is generally harmless itself, it can have a significant impact on the patient's well‐being as an obvious mark of the disease. DMC causes a grey or brown discoloration of the skin and mucous membranes. We report on a young
Christiane Cussigh   +3 more
wiley   +1 more source

Pilot Study of Tildrakizumab in the Treatment of Stable Non‐Segmental Vitiligo

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Treatment for vitiligo is limited, with variable efficacy, and can be time‐consuming or expensive. Recent developments within biologic therapy have demonstrated promising results with managing chronic autoimmune conditions. Objectives To evaluate the efficacy of tildrakizumab in inducing repigmentation in vitiligo.
Henry Lee   +13 more
wiley   +1 more source

Differentiation of cultured hair follicle neural crest stem cells into functional melanocytes

open access: yesHeliyon
Many autologous melanocytes are required for surgical treatment of depigmentation diseases such as vitiligo. However, primary cultured melanocytes have a limited number of in vitro passages.
Hongjuan Wang   +7 more
doaj  

A melanocytic cuckoo [PDF]

open access: yesJAAD Case Reports, 2018
Birgit Pees   +3 more
openaire   +3 more sources

Recent Advancements in the Characterization of D‐Amino Acid and Isoaspartate Post‐Translational Modifications

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT One of the great triumphs of mass spectrometry‐based peptide and protein characterization is the characterization of their modifications as most modifications have a characteristic mass shift. What happens when the modification does not change the mass of the peptide?
Samuel Okyem, Jonathan V. Sweedler
wiley   +1 more source

Effectiveness of Two Phytochemicals, P-Coumaric Acid and Quercetin in Reducing the Melanin Content of Pigmented Gingival Tissue: An Ex-vivo Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Introduction: Pigmented gingiva is an aesthetic concern for many individuals. Various treatment modalities have been developed to address this condition, but each carries certain disadvantages.
Shubhangi Behl   +2 more
doaj   +1 more source

Aetiology and treatment of epidermal depigmentory disorder in humans [PDF]

open access: yes, 2012
The epidermal depigmentary trigger in humans at post-natal level may occur with the toxification of skin organ with the endogenously produced melanocytotoxic hydrogen peroxide and subsequent formation of hydrogen peroxide- melanolipoprotein conjugate ...
S. S. Sawhney
core   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

open access: yesMed Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin   +8 more
wiley   +1 more source

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