Results 141 to 150 of about 116,555 (410)

High charge of cerebroid nests in nodular melanomas predicts tumor aggressiveness and high mutational tumoral burden: a pilot study

open access: yesFrontiers in Oncology
PurposeEven today, melanoma is a highly aggressive neoplasm with a high mortality rate. The nodular type is very aggressive and has cerebroid nests of melanocytes (CNMs) at the growth edge, morphologically similar to the poorly differentiated neoplastic ...
Stefania Caramaschi   +12 more
doaj   +1 more source

A Dense CNN approach for skin lesion classification [PDF]

open access: yesarXiv, 2018
This article presents a Deep CNN, based on the DenseNet architecture jointly with a highly discriminating learning methodology, in order to classify seven kinds of skin lesions: Melanoma, Melanocytic nevus, Basal cell carcinoma, Actinic keratosis / Bowen's disease, Benign keratosis, Dermatofibroma, Vascular lesion.
arxiv  

Shedding light on melanins within in situ human eye melanocytes using 2-photon microscopy profiling techniques. [PDF]

open access: yes, 2019
Choroidal melanocytes (HCMs) are melanin-producing cells in the vascular uvea of the human eye (iris, ciliary body and choroid). These cranial neural crest-derived cells migrate to populate a mesodermal microenvironment, and display cellular functions ...
Cherepanoff, Svetlana   +6 more
core  

Cryomicroneedle Arrays for Biotherapeutics Delivery

open access: yesSmall Science, EarlyView.
CryoMNs for biotherapeutic delivery to treat various diseases. CryoMNs: cryomicroneedles. Biotherapy offers a promising approach for treating a variety of diseases. However, the lack of advanced delivery systems remains a significant barrier to improve the efficacy, safety, and cost‐effectiveness of biotherapeutics.
Chunli Yang   +9 more
wiley   +1 more source

Elastic Properties of Nematic Liquid Crystals Formed by Living and Migrating Cells [PDF]

open access: yesarXiv, 1998
In culture migrating and interacting amoeboid cells can form nematic liquid crystal phases. A polar nematic liquid crystal is formed if the interaction has a polar symmetry. One type of white blood cells (granulocytes) form clusters where the cells are oriented towards the center.
arxiv  

Mechanistic studies of anti-hyperpigmentary compounds: elucidating their inhibitory and regulatory actions. [PDF]

open access: yes, 2014
Searching for depigmenting agents from natural sources has become a new direction in the cosmetic industry as natural products are generally perceived as relatively safer.
Cheng, CH   +3 more
core   +2 more sources

A call to integrate non‐visual functions of pigments and their interactions with visual functions to understand global change impacts on visual systems

open access: yesFunctional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Animal coloration serves a variety of visually related functions in nature (e.g. mate choice, aposematism and camouflage) but the pigments in integumentary tissues such as skin, scales and feathers may also serve functions unrelated to the visual environment (e.g ...
Beth A. Reinke   +2 more
wiley   +1 more source

The triennial International Pigment Cell Conference (IPCC) [PDF]

open access: yesarXiv, 2018
The International Federation of Pigment Cell Societies (IFPCS) held its XXIII triennial International Pigment Cell Conference (IPCC) in Denver, Colorado in August 2017. The goal of the summit was to provide a venue promoting a vibrant interchange among leading basic and clinical researchers working on leading-edge aspects of melanocyte biology and ...
arxiv  

Early- and late-migrating cranial neural crest cell populations have equivalent developmental potential in vivo [PDF]

open access: yes, 1997
We present the first in vivo study of the long-term fate and potential of early-migrating and late-migrating mesencephalic neural crest cell populations, by performing isochronic and heterochronic quail-to-chick grafts.
Baker, Clare V. H.   +3 more
core  

Technical Note: The Use of RNA-interference as a Tool to Find Proteins Involved in Melanosome Formation or Transport [PDF]

open access: yes, 2009
Melanosomes are lysosome-related organelles that produce and transport the pigment melanin within melanocytes. Mutations in proteins required for melanosome transport and formation lead to a range of pigmentation defects, manifested at the cellular level
Daniela Rotin, Eva M. Amsen
core   +2 more sources

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