Results 141 to 150 of about 123,035 (391)
Determining the Characteristic Vocabulary for a Specialized Dictionary using Word2vec and a Directed Crawler [PDF]
, 2016 Specialized dictionaries are used to understand concepts in specific domains, especially where those concepts are not part of the general vocabulary, or having meanings that differ from ordinary languages.
Grefenstette, Gregory, Muchemi, Lawrence
core +3 more sources
Nuclear Alpha‐Synuclein: Mechanisms and Implications for Synucleinopathies
Movement Disorders, EarlyView.Abstract Alpha‐synuclein (aSyn), historically studied for its synaptic functions and central role in Lewy body pathology, is emerging as a protein with significant nuclear activities relevant to Parkinson's disease (PD) and related synucleinopathies. Recent advances reveal that aSyn dynamically localizes to neuronal nuclei in both health and disease ...
Tiago Fleming Outeiro, David J. Koss
wiley +1 more source
Vesicular Stomatitis Virus Variants Selectively Infect and Kill Human Melanomas but Not Normal Melanocytes [PDF]
, 2013 Guido Wollmann +3 more
openalex +1 more source
Exploration of Therapeutic Targets Using CDK4 Inhibitors for Head and Neck Mucosal Melanoma
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective Mucosal melanoma (MM) is an extremely aggressive malignant tumor in the head and neck region associated with a poor prognosis. In the present study, we conducted cell proliferation assay and western blotting using cell lines derived from MM and the immunohistochemical analysis of pathological MM tissues to identify novel therapeutic ...
Takayoshi Hattori +14 more
wiley +1 more source
The Journal of Pathology, EarlyView.Abstract Netherton syndrome (NS) is a rare, severe, and often life‐threatening disease for which current therapeutic approaches are limited and show variable effectiveness. NS is characterized by excessive epidermal desquamation that results in a highly defective epidermal barrier, constitutive skin inflammation, allergies, and hair abnormalities.
Eleni Zingkou +3 more
wiley +1 more source
Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy
Phytotherapy Research, EarlyView.Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee +9 more
wiley +1 more source
PEARL: Protein Eluting Alginate with Recombinant Lactobacilli
Small, EarlyView.Probiotic lactobacilli meet engineered living materials: This study introduces PEARL (protein eluting alginate with recombinant lactobacilli), an innovative engineered living material combining Lactiplantibacillus plantarum and alginate beads for controlled protein release.
Varun Sai Tadimarri +7 more
wiley +1 more source