Results 11 to 20 of about 116,555 (410)

Melanocytes and their diseases. [PDF]

open access: yesCold Spring Harbor Perspectives in Medicine, 2014
Human melanocytes are distributed not only in the epidermis and in hair follicles but also in mucosa, cochlea (ear), iris (eye), and mesencephalon (brain) among other tissues.
Y. Yamaguchi, V. Hearing
semanticscholar   +4 more sources

Melanocytes, melanocyte stem cells, and melanoma stem cells. [PDF]

open access: yesClinics in Dermatology, 2013
Melanocyte stem cells differ greatly from melanoma stem cells; the former provide pigmented cells during normal tissue homeostasis and repair, and the latter play an active role in a lethal form of cancer. These 2 cell types share several features and can be studied by similar methods.
D. Lang, J. Mascarenhas, C. Shea
semanticscholar   +4 more sources

MITF in Normal Melanocytes, Cutaneous and Uveal Melanoma: A Delicate Balance

open access: yesInternational Journal of Molecular Sciences, 2022
Microphthalmia-associated transcription factor (MITF) is an important regulator of melanogenesis and melanocyte development. Although it has been studied extensively in cutaneous melanoma, the role of MITF in uveal melanoma (UM) has not been explored in ...
M. Gelmi   +4 more
semanticscholar   +1 more source

Successful Repigmentation of Full-Thickness Wound Healing in Fraser’s Dolphins (Lagenodelphis hosei)

open access: yesAnimals, 2022
Fraser’s dolphins (Lagenodelphis hosei) exhibit the capability to restore nearly normal pigmentation after full-thickness wounding. However, the association among melanocytes, melanin and skin pigmentation during wound healing in cetaceans has yet to be ...
Chen-Yi Su   +5 more
doaj   +1 more source

The genomic landscapes of individual melanocytes from human skin

open access: yesbioRxiv, 2020
Every cell in the human body has a unique set of somatic mutations, but it remains difficult to comprehensively genotype an individual cell 1 . Here we describe ways to overcome this obstacle in the context of normal human skin, thus offering a glimpse ...
Jessica Tang   +13 more
semanticscholar   +1 more source

Classification of Melanocytic Nevus Images using BigTransfer (BiT) [PDF]

open access: yes, 2022
Skin cancer is a fatal disease that takes a heavy toll over human lives annually. The colored skin images show a significant degree of resemblance between different skin lesions such as melanoma and nevus, making identification and diagnosis more challenging. Melanocytic nevi may mature to cause fatal melanoma.
arxiv   +1 more source

Melanocytic schwannoma [PDF]

open access: yesCancer, 1988
The clinical, histopathologic, immunohistochemical, and electron microscopic findings of two cases of melanocytic schwannoma are reported. One case, which occurred in the parotid gland, is believed to be the first reported in this location. The other case was located in the sacral spinal region.
Roberta M. Killeen   +2 more
openaire   +3 more sources

Functional and long-lived melanocytes from human pluripotent stem cells with transient ectopic expression of JMJD3

open access: yesStem Cell Research & Therapy, 2023
Background Melanocytes are an essential part of the epidermis, and their regeneration has received much attention because propagation of human adult melanocytes in vitro is too slow for clinical use.
Chie Kobori   +10 more
doaj   +1 more source

Melanoma Risk and Melanocyte Biology

open access: yesActa Dermato-Venereologica, 2020
Cutaneous melanoma arises from melanocytes following genetic, epigenetic and allogenetic (i.e. other than epi/genetic) modifications. An estimated 10% of cutaneous melanoma cases are due to inherited variants or de novo mutations in approximately 20 ...
Julie U. Bertrand   +4 more
doaj   +1 more source

Loss of Melanopsin (OPN4) Leads to a Faster Cell Cycle Progression and Growth in Murine Melanocytes

open access: yesCurrent Issues in Molecular Biology, 2021
Skin melanocytes harbor a complex photosensitive system comprised of opsins, which were shown, in recent years, to display light- and thermo-independent functions.
Leonardo Vinícius Monteiro de Assis   +5 more
doaj   +1 more source

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