Results 31 to 40 of about 48,156 (309)
Alpha-Synuclein and Its Role in Melanocytes
Cells, 2022 Pigmentation is an important process in skin physiology and skin diseases and presumably also plays a role in Parkinson’s disease (PD). In PD, alpha-Synuclein (aSyn) has been shown to be involved in the pigmentation of neurons. The presynaptic protein is
Nicole Rachinger +5 more
doaj +1 more source
Melanocytic Nevus of the Colon [PDF]
Case Reports in Gastroenterology, 2019 Here, we report a very rare case of melanocytic nevus of the colon. A 54-year-old woman with an unremarkable medical history visited our hospital for screening colonoscopy. Colonoscopy revealed a pigmented flat lesion in the ascending colon. Histological evaluation of a biopsy specimen revealed proliferation of pigmented cells in the lamina muscularis ...
Tamotsu Sugai +5 more
openaire +3 more sources
The role of extracellular vesicles in cutaneous remodeling and hair follicle dynamics [PDF]
, 2019 Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, are cell-derived membranous structures that were originally catalogued as a way of releasing cellular waste products.
Carrasco, Elisa +2 more
core +2 more sources
Journal of the Egyptian Women’s Dermatologic Society, 2020 Background Treatment of vitiligo not responding to conventional therapies involves the replacement of the absent melanocytes by surgical maneuvers, including minigrafting and cultured and noncultured cell suspension grafting.
Tag S Anbar +3 more
doaj +1 more source
PLoS ONE, 2020 OBJECTIVE:Melanocytes play a central role in skin homeostasis. In this study, we focus on the function of melanocyte releasing exosomes as well as exosomal microRNAs (miRNAs) and investigate whether ultraviolet B (UVB) irradiation exerts an impact on it.
Zeren Shen +3 more
doaj +1 more source
, 2018 Mucosal nasopharyngeal melanoma is a rare head and neck melanoma. Prognosis is poor (5-year overall survival rate of 10–30%) with high rates of metastases and local recurrence. Head and neck mucosal melanoma represents 0.8–3.7% of all melanomas and 0.03%
Calvieri, Stefano +4 more
core +1 more source
Journal of Investigative Dermatology, 1979 Choroidal melanocytes of the eyes of postnatal animals are classified as postmitotic terminally differentiated cells. They have specific granules, the melanosomes, which undergo changes qualitatively and quantitatively correlated to the animal's increasing age.
openaire +3 more sources
Regenerative Medicine-Based Treatment for Vitiligo: An Overview
Biomedicines, 2022 Vitiligo is a complex disorder with an important effect on the self-esteem and social life of patients. It is the commonest acquired depigmentation disorder characterized by the development of white macules resulting from the selective loss of epidermal ...
Barbara Bellei +2 more
doaj +1 more source
Melanocytes and Skin Immunity [PDF]
Journal of Investigative Dermatology Symposium Proceedings, 2015 Melanocytes in skin are melanin-producing cells that are derived from the neural crest. They migrate during embryological development and localize in the epidermis and hair follicles where they pigment skin and hair (Nishimura, 2011). Melanocytes and their production of melanin pigment (a process termed melanogenesis) have important roles in cutaneous ...
Xing-Hua Gao +3 more
openaire +3 more sources
MicroRNAs in melanoma development and resistance to target therapy [PDF]
, 2017 microRNAs constitute a complex class of pleiotropic post-transcriptional regulators of gene expression involved in the control of several physiologic and pathologic processes.
Ascierto, Paolo Antonio +7 more
core +1 more source