A newborn with a rare association of various congenital skin disorders – Question
Journal of Pediatric and Neonatal Individualized Medicine, 2022 We report the case of a female term neonate admitted for congenital skin anomalies to a Neonatology Department a few hours after birth. Pregnancy and vaginal delivery were uneventful.
Federico Mecarini +2 more
doaj +1 more source
Imiquimod induced vitiligo‐like lesions—A consequence of modified melanocyte function
Immunity, Inflammation and Disease, 2022 Introduction Imiquimod plays an important role in the management of condyloma and premalignant lesions. Successively, an increase of hypopigmented lesions following imiquimod application has been reported.
Haiyan Yu +4 more
doaj +1 more source
Agouti protein, mahogunin, and attractin in pheomelanogenesis and melanoblast-like alteration of melanocytes: a cAMP-independent pathway [PDF]
, 2009 Melanocortin-1 receptor (MC1R) and its ligands, a-melanocyte stimulating hormone (aMSH) and agouti signaling protein (ASIP), regulate switching between eumelanin and pheomelanin synthesis in melanocytes.
Abdel-Malek +45 more
core +2 more sources
The biology of melanocyte and melanocyte stem cell [PDF]
Acta Biochimica et Biophysica Sinica, 2014 The melanocyte stem cells of the hair follicle provide an attractive system for the study of the stem cells. Successful regeneration of a functional organ relies on the organized and timely orchestration of molecular events among distinct stem/progenitor cell populations.
openaire +3 more sources
In vitro evidence for senescent multinucleated melanocytes as a source for tumor-initiating cells [PDF]
, 2015 Oncogenic signaling in melanocytes results in oncogene-induced senescence (OIS), a stable cell-cycle arrest frequently characterized by a bi- or multinuclear phenotype that is considered as a barrier to cancer progression.
Bröcker, E.-B. +12 more
core +2 more sources
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance This study expands understanding of opsin 3 (OPN3) function and of skin pigmentation. The findings presented here reveal that the nonvisual OPN3 modulates the pigmentation of human epidermal melanocytes—the melanin-producing cells of the ...
Rana N. Ozdeslik +4 more
semanticscholar +1 more source
Vitiligo and autoimmune thyroid disorders [PDF]
, 2017 Vitiligo represents the most common cause of acquired skin, hair and oral depigmentation, affecting 0.5-1% of the population worldwide. It is clinically characterized by the appearance of disfiguring circumscribed skin macules following melanocyte ...
Baldini, Enke +10 more
core +2 more sources
Fascin 1 is transiently expressed in mouse melanoblasts during development and promotes migration and proliferation [PDF]
, 2013 Fascins, a family of actin-bundling proteins, are expressed in a spatially and temporally restricted manner during development and often in cancer.
Ackermann +52 more
core +3 more sources
Dowling-Degos Disease: Case Report and Review of the Literature [PDF]
, 2010 Dowling-Degos disease (DDD) is an unusual pigmentary disorder usually caused by mutations in keratin 5. A 44-year-old woman in good general health presented due to the recent appearance of numerous pigmented macules on her axillary and anogenital skin. A
Baran, Wojciech +3 more
core +1 more source
Instructive role of melanocytes during pigment pattern formation of the avian skin
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Periodic pigment patterns, such as spots and stripes, are often observed in animal skin; however, we should learn more the molecular and cellular mechanisms for patterning. Here, we examined the black and yellow stripes in the Japanese quail
Masafumi Inaba +6 more
semanticscholar +1 more source