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Melanocytes and Skin Immunity [PDF]
Journal of Investigative Dermatology Symposium Proceedings, 2015 Melanocytes in skin are melanin-producing cells that are derived from the neural crest. They migrate during embryological development and localize in the epidermis and hair follicles where they pigment skin and hair (Nishimura, 2011). Melanocytes and their production of melanin pigment (a process termed melanogenesis) have important roles in cutaneous ...
Xing-Hua Gao +3 more
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Current Concepts of Vitiligo Immunopathogenesis
Biomedicines, 2022 Vitiligo is an acquired immune-mediated disorder of pigmentation clinically characterized by well-defined depigmented or chalk-white macules and patches on the skin.
Nika Hlača +4 more
doaj +1 more source
Caveolin-1 is a risk factor for postsurgery metastasis in preclinical melanoma models [PDF]
, 2014 Melanomas are highly lethal skin tumours that are frequently treated by surgical resection. However, the efficacy of such procedures is often limited by tumour recurrence and metastasis. Caveolin-1 (CAV1) has been attributed roles as a tumour suppressor,
Aguilar-Guzmán, L +11 more
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Alpha-Synuclein and Its Role in Melanocytes
Cells, 2022 Pigmentation is an important process in skin physiology and skin diseases and presumably also plays a role in Parkinson’s disease (PD). In PD, alpha-Synuclein (aSyn) has been shown to be involved in the pigmentation of neurons. The presynaptic protein is
Nicole Rachinger +5 more
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Melanocytes, melanocyte stem cells, and melanoma stem cells [PDF]
Clinics in Dermatology, 2013 Melanocyte stem cells differ greatly from melanoma stem cells; the former provide pigmented cells during normal tissue homeostasis and repair, and the latter play an active role in a lethal form of cancer. These 2 cell types share several features and can be studied by similar methods.
Joseph B. Mascarenhas +2 more
openaire +3 more sources
Regenerative Medicine-Based Treatment for Vitiligo: An Overview
Biomedicines, 2022 Vitiligo is a complex disorder with an important effect on the self-esteem and social life of patients. It is the commonest acquired depigmentation disorder characterized by the development of white macules resulting from the selective loss of epidermal ...
Barbara Bellei +2 more
doaj +1 more source
Graded potential of neural crest to form cornea, sensory neurons and cartilage along the rostrocaudal axis [PDF]
, 2004 Neural crest cells arising from different rostrocaudal axial levels form different sets of derivatives as diverse as ganglia, cartilage and cornea. These variations may be due to intrinsic properties of the cell populations, different environmental ...
Bronner-Fraser, Marianne +2 more
core +2 more sources
Liquid Crystalline Networks Hamper the Malignancy of Cancer Cells
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.Liquid Crystalline Networks are used as scaffolds for the growth of A375 melanoma cells demonstrating to affect their malignancy. Indeed, only by contact, these materials reduces cell proliferation and colony formation capacity, while increasing the number of senescent cells and promoting the mesenchymal to epithelial transition.
Daniele Martella +9 more
wiley +1 more source
Human cutaneous interfollicular melanocytes differentiate temporarily under genotoxic stress
iScience, 2022 Summary: DNA-damage response of cutaneous interfollicular melanocytes to fractionated radiotherapy was investigated by immunostaining of tissue sections from punch biopsies collected before, during, and after the treatment of patients for breast cancer ...
Per Fessé +5 more
doaj
Frontiers in Pigment Cell and Melanoma Research
, 2018 We identify emerging frontiers in clinical and basic research of melanocyte biology and its associated biomedical disciplines. We describe challenges and opportunities in clinical and basic research of normal and diseased melanocytes that impact current ...
Birlea, Stanca +26 more
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