Results 41 to 50 of about 29,468 (254)
Mechanism of Mitf inhibition and morphological differentiation effects of hirsein A on B16 melanoma cells revealed by DNA microarray [PDF]
, 2012 BackgroundWe have previously reported that hirsein A inhibits melanogenesis in B16 melanoma cells by downregulating the Mitf gene expression.ObjectiveIn this study, microarray was employed to determine the transcriptional response of B16 cells to hirsein
Han Junkyu +5 more
core +1 more source
Melanogenesis in Cryptococcus neoformans [PDF]
Microbiology, 1988 Melanogenesis in Cryptococcus neoformans begins with the oxidation of dihydroxyphenylalanine by the enzyme phenol oxidase. The succeeding steps are very rapid. Two intermediates, dopachrome and 5,6-dihydroxyindole, have been isolated and characterized by high performance liquid chromatography. A pathway of melanin formation in C. neoformans is proposed,
I, Polacheck, K J, Kwon-Chung
openaire +2 more sources
BMC Genomics, 2022 Background Melanin is an important antioxidant in food and has been used in medicine and cosmetology. Chicken meat with high melanin content from black-boned chickens have been considered a high nutritious food with potential medicinal properties.
Tengfei Dou +25 more
doaj +1 more source
Scientific ReportsAlthough previous studies have examined the signaling pathway involved in melanogenesis through which ultraviolet (UV) or α-melanocyte-stimulating hormones (α-MSH) stimuli act as key inducers to produce melanin at the stratum basal layer of the epidermis,
Dohyun Jeung +13 more
doaj +1 more source
Annals of Human BiologyBackground Vitiligo is an autoimmune disorder marked by melanocyte destruction and skin depigmentation.Aim To explore the molecular mechanisms underlying melanogenesis and their link to vitiligo.Subjects and methods We analysed three vitiligo-related ...
Binxi Ma, Xiao Wang
doaj +1 more source
Animal, 2017 It has been demonstrated that microRNAs (miRNAs) play important roles in the control of melanogenesis and hair color in mammals. By comparing miRNA expression profiles between brown and white alpaca skin, we previously identified miR508-3p as a ...
J. Zhang +9 more
doaj +1 more source
Molecules, 2020 Previous studies have reported that estrogen hormone promotes melanogenesis while progesterone inhibits it. A selective estrogen receptor modulator (SERM), tamoxifen, has been shown to promote melanogenesis; however, to date, there have been no reports ...
Shilpi Goenka, Sanford R. Simon
doaj +1 more source
Melanogenesis and the Targeted Therapy of Melanoma
Biomolecules, 2022 Pigment production is a unique character of melanocytes. Numerous factors are linked with melanin production, including genetics, ultraviolet radiation (UVR) and inflammation.
Cang Li, Le Kuai, Rutao Cui, Xiao Miao
doaj +1 more source
Skin Lightening Treatments: A Review on the Effect of Intravenous Glutathione in the Disease States of Women [PDF]
, 2020 The skin bleaching industry is a global business with a vast array of anti-melanogenic choices including glutathione. Glutathione is synthesized in vivo but has been used as a bodily supplement by medical personnel to aid in preventative medicine.
Mthombeni, Buhle
core +1 more source
Advanced Functional Materials, EarlyView.Quantum sensing reveals intricate patterns linking endo‐lysosomal maturation to cardiac fibrosis progression, highlighting complexity in cellular remodeling. This study investigates fibroblast‐to‐myofibroblast transition under cell aging, stiffness, and TGF‐β stimulation, comparing nanodiamond uptake, endo‐lysosomal dynamics, and free radical ...
Aldona Mzyk +3 more
wiley +1 more source