Results 71 to 80 of about 29,468 (254)
FoxO6 inhibits melanogenesis partly by elevating intracellular antioxidant capacity
Redox Biology, 2020 Of the various transcription factors that play a role in controlling oxidative stress, the role of FoxO proteins in skin aging has recently become of interest.
Kyoung Mi Moon +3 more
doaj +1 more source
Dynamics of Melanogenesis Intermediates.
Journal of Investigative Dermatology, 1993 The course of melanogenesis in (malignant) melanocytes is determined by several relatively independent metabolic processes such as tyrosine uptake and compartmentation, the activity of tyrosinase, and the capacity of melanosomes to produce and store melanin. There is experimental evidence that tyrosine is transported across the cell membrane with a Na(+
openaire +2 more sources
Integrative Zoology, EarlyView.This study compared the ecological toxicity of organic ultraviolet filters, octocrylene (OC) and ethylhexyl salicylate (EHS), on zebrafish embryos and larvae. EHS exhibited higher acute toxicity, causing increased mortality, hypoactive behavior at 50 mg/L, and disruptions in lipid homeostasis, while OC primarily affected hypoxia response and ...
Xiaoyang Lu +5 more
wiley +1 more source
Melasma pathogenesis: a review of the latest research, pathological findings, and investigational therapies [PDF]
, 2019 Melasma is an acquired hyperpigmentation disorder most commonly affecting females with darker skin types. It is triggered by several factors including sun exposure, genetic influences, and female sex hormones.
Maymone, Mayra BC de Castro +2 more
core
Haplotype differences for copy number variants in the 22q11.23 region among human populations: a pigmentation-based model for selective pressure. [PDF]
, 2014 Two gene clusters are tightly linked in a narrow region of chromosome 22q11.23: the macrophage migration inhibitory factor (MIF) gene family and the glutathione S-transferase theta class.
A Enomoto +51 more
core +1 more source
Melanogenesis inhibition by tetrahydropterines
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2009 There is controversy in the literature concerning the action of tetrahydropterines on the enzyme tyrosinase and on melanogenesis in general. In this study, we demonstrate that tetrahydropterines can inhibit melanogenesis in several ways: i) by non-enzymatic inhibition involving purely chemical reactions reducing o-dopaquinone to L-dopa, ii) by acting ...
García Molina, Francisco +6 more
openaire +3 more sources
Clear cell sarcoma with melanogenesis [PDF]
Cancer, 1978 An example of clear cell sarcoma, from the great toe of a young woman having an otherwise classic history and appearance is described, and a malignant giant cell component is reported for the first time. Histochemical and electron microscopic studies clearly demonstrate melanogenesis.
D, Boudreaux, J, Waisman
openaire +2 more sources
Australasian Journal of Dermatology, EarlyView.ABSTRACT Background/Objectives Post‐inflammatory hyperpigmentation (PIH) is a frequent sequela of acne in patients with skin of colour (SOC). While sunscreen is widely recommended for PIH prevention, little is known about real‐world sunscreen practices in this group. This study aimed to evaluate sunscreen use, barriers and factors influencing adherence
Xiaozhun Hang, Davin Sui Lim, Lisa Byrom
wiley +1 more source
Condition-dependence, pleiotropy and the handicap principle of sexual selection in melanin-based colouration. [PDF]
, 2015 The signalling function of melanin-based colouration is debated. Sexual selection theory states that ornaments should be costly to produce, maintain, wear or display to signal quality honestly to potential mates or competitors.
Roulin, A.
core +1 more source
British Journal of Pharmacology, EarlyView.Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi +10 more
wiley +1 more source