Results 91 to 100 of about 26,405 (229)

Occupational Exposure to Factory‐Derived Particulate Matter 2.5 Induces Cutaneous Toxicity in Workers and HaCaT Keratinocytes Through Oxidative Stress and Inflammation

open access: yesJournal of Applied Toxicology, Volume 46, Issue 6, Page 2145-2157, June 2026.
ABSTRACT This study aimed to evaluate the toxicological effects of occupational exposure to factory‐derived particulate matter (PM2.5) on human skin, emphasizing its role as a potential target organ of environmental toxicants. An epidemiological survey comparing factory and nonfactory workers was conducted by assessing their skin elasticity and color ...
Miku Tanaka   +7 more
wiley   +1 more source

Fluorescent quantification of melanin [PDF]

open access: yes, 2016
Melanin quantification is reportedly performed by absorption spectroscopy, commonly at 405 nm. Here, we propose the implementation of fluorescence spectroscopy for melanin assessment.
Baek   +11 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, Volume 20, Issue 5, Page 1185-1201, May 2026.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Shedding light on melanins within in situ human eye melanocytes using 2-photon microscopy profiling techniques. [PDF]

open access: yes, 2019
Choroidal melanocytes (HCMs) are melanin-producing cells in the vascular uvea of the human eye (iris, ciliary body and choroid). These cranial neural crest-derived cells migrate to populate a mesodermal microenvironment, and display cellular functions ...
Cherepanoff, Svetlana   +6 more
core  

Hair coloration by gene regulation: fact or fiction? [PDF]

open access: yes, 2015
The unravelling of hair pigmentation genetics and robust delivery systems to the hair follicle (HF) will allow the development of a new class of colouring products.
Branicki   +11 more
core   +1 more source

Nanodiamond‐Based Quantum Sensing Reveals Changes in Endo‐Lysosomal Activity of Stimulated Cardiac Fibroblasts in a Cellular Fibrosis Model

open access: yesAdvanced Functional Materials, Volume 36, Issue 36, 4 May 2026.
Quantum sensing reveals intricate patterns linking endo‐lysosomal maturation to cardiac fibrosis progression, highlighting complexity in cellular remodeling. This study investigates fibroblast‐to‐myofibroblast transition under cell aging, stiffness, and TGF‐β stimulation, comparing nanodiamond uptake, endo‐lysosomal dynamics, and free radical ...
Aldona Mzyk   +3 more
wiley   +1 more source

ULK1 regulates melanin levels in MNT-1 cells independently of mTORC1.

open access: yesPLoS ONE, 2013
Melanosomes are lysosome-related organelles that serve as specialized sites of melanin synthesis and storage in melanocytes. The progression of melanosomes through the different stages of their formation requires trafficking of specific proteins and ...
Eyal Kalie, Minoo Razi, Sharon A Tooze
doaj   +1 more source

Photophysics of Biological and Biomimetic Sunscreen Molecules

open access: yesChemPhotoChem, Volume 10, Issue 5, May 2026.
Recent photochemical and photophysical research into natural and nature‐inspired UV filter molecules is reviewed, with a focus on the application of these systems in next‐generation sunscreens. The results of time‐resolved UV spectroscopy experiments and theoretical studies are discussed.
Michael Hymas, Vasilios G. Stavros
wiley   +1 more source

Screening of Key Components for Melanogenesis Inhibition of Polygonum cuspidatum Extract Based on the Spectrum–Effect Relationship and Molecular Docking

open access: yesMolecules
Polygonum cuspidatum (PC) extract has been listed in the “Catalog of Used Cosmetic Ingredients (2021 Edition)”, which can inhibit melanogenesis, thus exerting a whitening effect, and has been widely used in cosmetics.
Ruojun Du   +8 more
doaj   +1 more source

Vital dye labelling of Xenopus laevis trunk neural crest reveals multipotency and novel pathways of migration [PDF]

open access: yes, 1993
Although the Xenopus embryo has served as an important model system for both molecular and cellular studies of vertebrate development, comparatively little is known about its neural crest.
Bronner-Fraser, Marianne   +2 more
core  

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