Results 101 to 110 of about 18,845 (218)

Melanogenesis Inhibitory Activity of Two Generic Drugs: Cinnarizine and Trazodone in Mouse B16 Melanoma Cells

, 2011
More than 200 generic drugs were screened to identify the inhibitory activity on melanogenesis in mouse B16 melanoma cells. Cinnarizine and trazodone were identified as melanogenesis inhibitors.
Te-Sheng Chang, Victor Chia-Hsiang Lin
core   +1 more source

Activators of melanogenesis

reservedMelanin is a mixture of natural pigments that plays an important role in cell protection against UV-radiation induced damage. It is produced in the basal layer of the epidermis by specialised dendritic cells.
PACCAGNELLA, THOMAS
core  

Inhibition of Melanogenesis via Passive Immune Targeted Alpha-MSH Binder Polypeptide

Cosmetics
Alpha-melanocyte stimulating hormone (α-MSH) is a hormone that stimulates the formation of melanin, which is responsible for protecting the skin from UV rays.
Se-Hyo Jeong, Hun-Hwan Kim, Abigail Joy D. Rodelas-Angelia, Mark Rickard N. Angelia, Pritam Bhagwan Bhosale, Eun-Hye Kim, Tae-Sung Jung, Mee-Jung Ahn, Gon-Sup Kim   +8 more
doaj   +1 more source

Serotonin induces melanogenesis via serotonin receptor 2A

, 2019
Background Serotonin (5-hydroxytryptamine, 5-HT) levels are increased by light exposure but the role and mechanism of 5-HT in the pigmentation of skin cells are unclear.
박혜영
core   +1 more source

Apigenin and Phloretin Combination for Skin Aging and Hyperpigmentation Regulation

Cosmetics
Melasma is a pathology with multifactorial causes that results in hyperpigmentation of sun-exposed areas, particularly facial skin. New treatments targeting the different factors regulating this condition need to be effective with and have limited ...
Alfredo Martínez-Gutiérrez, Javier Sendros, Teresa Noya, Mari Carmen González   +3 more
doaj   +1 more source

Real-time RT-PCR analysis of melanogenesis-associated genes between the muzzle tissues of dark-muzzle HanWoo (DH) and light-muzzle HanWoo (LH).

, 2014
The bars represent the average fold changes from 3 independent experiments (±SD). A) Genes involved in the upstream pathways of melanogenesis. B) Genes involved in the downstream pathways of melanogenesis.
Sang Hwan Kim (303828), Sue Yun Hwang (561517), Jong Taek Yoon (303833)   +2 more
core   +1 more source

IDH2 deficiency accelerates skin pigmentation in mice via enhancing melanogenesis

, 2018
Melanogenesis is a complex biosynthetic pathway regulated by multiple agents, which are involved in the production, transport, and release of melanin. Melanin has diverse roles, including determination of visible skin color and photoprotection.
Jin Hyup Lee, Hyeong Jun Ku, Jung Hyun Park, Jeen-Woo Park   +3 more
core   +1 more source

Fermented Fish Collagen Attenuates Melanogenesis via Decreasing UV-Induced Oxidative Stress

Marine Drugs
Excessive melanogenesis leads to hyperpigmentation-related cosmetic problems. UV exposure increases oxidative stress, which promotes melanogenesis-related signal pathways such as the PKA, microphthalmia-associated transcription factor (MITF), tyrosinase (
Kyung-A Byun, So Young Lee, Seyeon Oh, Sosorburam Batsukh, Jong-Won Jang, Bae-Jin Lee, Kyoung-min Rheu, Sichao Li, Min-Seok Jeong, Kuk Hui Son, Kyunghee Byun   +10 more
doaj   +1 more source

Human placental lipid induces melanogenesis through p38 MAPK in B16F10 mouse melanoma

, 2005
Melanogenesis is one of the characteristic functional activities of melanocyte/melanoma and is regulated via mitogen-activated protein kinase (MAPK) and Akt/protein kinase B (PKB) pathways.
Mallick, Shampa, Bera, Rabindranath, Singh, Suman Kumar, Bhadra, Ranjan, Sarkar, Chinmoy, Saha, Bidisha   +5 more
core   +1 more source

Melanogenesis in freckles patients analysis in facultative color of Melayu ethnic with skin phototype IV & V

, 2015
Background: Patients with lack of DNA repair capacity syndrome prone to have skin cancers and usually have freckles on their skin. Freckles is considered as a risk factor for skin cancer.
Catharina Sagita, Catharina Sagita
core