Results 111 to 120 of about 26,405 (229)

Efficacy of 1064‐Nm Picosecond Nd: YAG Laser in Treating Facial Photoaging and Improving Skin Barrier Enhanced by a Multi‐Beneficial Composition Formulation: A Blinded Randomized Clinical Trial Study

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 5, May 2026.
ABSTRACT Background In recent years, skin photoaging has received increasing attention, and laser therapy has become the most commonly used treatment due to its safety and efficacy; emerging evidence suggests that adjunctive “integrated skincare” may enhance treatment benefits by reducing post‐procedural reactions and supporting skin barrier repair ...
Yixuan He   +4 more
wiley   +1 more source

Photoprotection by dietary phenolics against melanogenesis induced by UVA through Nrf2-dependent antioxidant responses

open access: yesRedox Biology, 2016
Dietary phenolics may play a protective role in UV-mediated skin pigmentation through their antioxidant and UV-absorbing actions. In this study, we investigated whether genetic silencing of Nrf2, regulating the transcription of antioxidant genes ...
Anyamanee Chaiprasongsuk   +4 more
doaj   +1 more source

Inonotus obliquus Extract as An Inhibitor of α-MSH-Induced Melanogenesis in B16F10 Mouse Melanoma Cells

open access: yesCosmetics, 2019
Melanogenesis is a biosynthetic pathway that produces the pigment melanin in human skin. The catalyzation of the key enzyme tyrosinase is the first step in melanogenesis, and the downregulation of tyrosinase enzyme activity is the most reported method ...
Eun Ji Lee, Hwa Jun Cha
doaj   +1 more source

5,6-dihydroxyindole-2-carboxylic acid (DHICA): a First Principles Density-Functional Study

open access: yes, 2004
We report first principles density functional calculations for 5,6-dihydroxyindole-2-carboxylic acid (DHICA) and several reduced forms. DHICA and 5,6-dihydroxyindole (DHI) are believed to be the basic building blocks of the eumelanins.
B.J. Powell   +29 more
core   +1 more source

Amine derivatives of furocoumarin induce melanogenesis by activating Akt/GSK-3β/β-catenin signal pathway

open access: yesDrug Design, Development and Therapy, 2019
Deng Zang,1,2 Chao Niu,1 Haji Akber Aisa1 1Key Laboratory of Plant Resources and Chemistry in Arid Regions, State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry ...
Zang D, Niu C, Niu C, Aisa HA
doaj  

Dihydroxynaphthalene-based mimicry of fungal melanogenesis for multifunctional coatings [PDF]

open access: yes
Material-independent adhesive action derived from polycatechol structures has been intensively studied due to its high applicability in surface engineering. Here, we for the first time demonstrate that a dihydroxynaphthalene-based fungal melanin mimetic,
Chang, YS, Jeon, JR, Le, TT
core   +1 more source

Apigenin and Phloretin Combination for Skin Aging and Hyperpigmentation Regulation

open access: yesCosmetics
Melasma is a pathology with multifactorial causes that results in hyperpigmentation of sun-exposed areas, particularly facial skin. New treatments targeting the different factors regulating this condition need to be effective with and have limited ...
Alfredo Martínez-Gutiérrez   +3 more
doaj   +1 more source

Inhibition of Melanogenesis via Passive Immune Targeted Alpha-MSH Binder Polypeptide

open access: yesCosmetics
Alpha-melanocyte stimulating hormone (α-MSH) is a hormone that stimulates the formation of melanin, which is responsible for protecting the skin from UV rays.
Se-Hyo Jeong   +8 more
doaj   +1 more source

The Role of Apoptosis in the Pathogenesis of Malignant Melanoma [PDF]

open access: yes, 2010
Malignant melanoma genesis is a very complex process that involves a sequence of pathogenetic cellular events. Mutation of various genes and numerous other cellular mechanisms play an important role in the course of malignant melanocyte alteration and ...
Ana Šešerko   +4 more
core   +1 more source

Fermented Fish Collagen Attenuates Melanogenesis via Decreasing UV-Induced Oxidative Stress

open access: yesMarine Drugs
Excessive melanogenesis leads to hyperpigmentation-related cosmetic problems. UV exposure increases oxidative stress, which promotes melanogenesis-related signal pathways such as the PKA, microphthalmia-associated transcription factor (MITF), tyrosinase (
Kyung-A Byun   +10 more
doaj   +1 more source

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