Results 271 to 280 of about 710,495 (352)

Nitrite Reductases in Biomedicine: From Natural Enzymes to Artificial Mimics. [PDF]

Research (Wash D C)
Zhu S, Liu Z, Hu B, Feng Y, Pan G.
europepmc   +1 more source

Probing Enzymatic Acetylation Events in Real Time With NMR Spectroscopy: Insights Into Acyl‐Cofactor Dependent p300 Modification of Histone H4

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Lysine acylation is a rapidly expanding class of post‐translational modifications with largely unexplored functional roles; the study of acylations beyond acetylation is especially impeded by limited methods for their preparation, detection, and characterization in vitro. We previously reported a nuclear magnetic resonance (NMR)‐based approach
Sophia M. Dewing, Scott A. Showalter
wiley   +1 more source

Structural Basis for the Catalysis and Substrate Specificity of a LarA Racemase with a Broad Substrate Spectrum. [PDF]

ACS Catal
Gatreddi S, Urdiain-Arraiza J, Desguin B, Hausinger RP, Hu J.   +4 more
europepmc   +1 more source

Formation of a β‐Endorphin Corona Mitigates Alzheimer's Amyloidogenesis

Small, EarlyView.
This study revealed the molecular mechanism of exercise‐induced β‐endorphin in suppressing the toxicity of Alzheimer's Aβ in vitro, in vivo and in silico. Abstract Senile plaques, comprised of nanosized aggregates of amyloid‐β (Aβ) peptides in the brain, are a pathological hallmark of Alzheimer's disease (AD).
Yunxiang Sun, Nicholas Andrikopoulos, Guofang Zhang, Yuying Liu, Xiufang Liang, Dongjie Li, Xiaoman Suo, Yue Wang, Yuhuan Li, Chuang Wang, Yang Li, Pu Chun Ke, Feng Ding   +12 more
wiley   +1 more source

Sulfur‐Doped Carbon Dots as a Highly Selective and Sensitive Fluorescent Probe for Copper Ion Detection in Biological Systems

Small, EarlyView.
Sulfur‐doped carbon dots (S_HICA) can be used as a selective and sensitive fluorescent probe for Copper ion (Cu2+) detection via fluorescence quenching. S_HICA demonstrates high biocompatibility, fluorescence stability, and Cu2+ selectivity, which highlights its potential as a diagnostic tool for copper‐related diseases. Fluorescence is quenched by the
Minyoung Jin, Sanghee Lee, Su been Lim, Minyoung Lee, Jungwon Park, Hyun‐Do Jung, Min‐Ho Kang, Kun Na   +7 more
wiley   +1 more source

Inter-cofactor protein remodeling rewires short-circuited transmembrane electron transfer. [PDF]

Commun Chem
Hanson DK, Buhrmaster JC, Wyllie RM, Tira GA, Faries KM, Holten D, Kirmaier C, Laible PD.   +7 more
europepmc   +1 more source

Nanoparticle Therapeutics in Clinical Perspective: Classification, Marketed Products, and Regulatory Landscape

Small, EarlyView.
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai, Dhwani Rana, Mitali Patel, Neha Bajwa, Rajendra Prasad, Lalitkumar K. Vora   +5 more
wiley   +1 more source

Role of intrarenal complement production in kidney transplantation. [PDF]

Clin Kidney J
Molinari P, Wadnerkar S, Ferrari KL, Castellano G, Chun N, Cravedi P.   +5 more
europepmc   +1 more source

Rapid Amplification and Detection of Single‐Stranded Nucleic Acids for Point‐of‐Care Diagnosis

Small Methods, EarlyView.
A rapid, point‐of‐care nucleic acid test can greatly benefit healthcare system by providing timely diagnosis for effective treatment and patient management, as well as supporting diseases surveillance for emerging pandemic diseases. Recent advancements in nucleic acids technology have led to rapid assays for single‐stranded nucleic acids that can be ...
Jinglin Fu, Qiaochu Zhang, Shiming Liu, Derek Puyat, Akshay Shah, Alireza Ebrahimimojarad, Sung Won Oh   +6 more
wiley   +1 more source