Results 51 to 60 of about 178,051 (334)

Crystallographic studies of the Escherichia coli quinol-fumarate reductase with inhibitors bound to the quinol-binding site [PDF]

, 2002
The quinol-fumarate reductase (QFR) respiratory complex of Escherichia coli is a four-subunit integral-membrane complex that catalyzes the final step of anaerobic respiration when fumarate is the terminal electron acceptor.
Cecchini, Gary, Croal, Laura R., Iverson, Tina M., Luna-Chavez, César, Rees, Douglas C.   +4 more
core   +1 more source

The tissue-specific Rep8/UBXD6 tethers p97 to the endoplasmic reticulum membrane for degradation of misfolded proteins.

PLoS ONE, 2011
The protein known as p97 or VCP in mammals and Cdc48 in yeast is a versatile ATPase complex involved in several biological functions including membrane fusion, protein folding, and activation of membrane-bound transcription factors.
Louise Madsen, Franziska Kriegenburg, Andrea Vala, Diana Best, Søren Prag, Kay Hofmann, Michael Seeger, Ian R Adams, Rasmus Hartmann-Petersen   +8 more
doaj   +1 more source

Vibrio natriegens as Host for Expression of Multisubunit Membrane Protein Complexes

Frontiers in Microbiology, 2018
Escherichia coli is a convenient host for the expression of proteins, but the heterologous production of large membrane protein complexes often is hampered by the lack of specific accessory genes required for membrane insertion or cofactor assembly.
Lena Schleicher, Valentin Muras, Björn Claussen, Jens Pfannstiel, Bastian Blombach, Pavel Dibrov, Günter Fritz, Günter Fritz, Julia Steuber   +8 more
doaj   +1 more source

Redox linked flavin sites in extracellular decaheme proteins involved in microbe-mineral electron transfer [PDF]

, 2015
Extracellular microbe-mineral electron transfer is a major driving force for the oxidation of organic carbon in many subsurface environments. Extracellular multi-heme cytochromes of the Shewenella genus play a major role in this process but the mechanism
A Okamoto, AC Mitchell, AGW Leslie, AM Waterhouse, AS Beliaev, CL Reardon, D Coursolle, D Ghosal, DE Ross, DJ Richardson, DJ Richardson, DJ Richardson, DK Thompson, E Marsili, ED Brutinel, F Sievers, GF White, GM Boratyn, GN Murshudov, I Letunic, JK Fredrickson, L Shi, L Shi, MJ Daly, MJ Daly, MJ Edwards, MJ Edwards, MJ Edwards, MY El-Naggar, P Taylor, PD Adams, RJ Morris, RS Hartshorne, S Bailey, S Pirbadian, TA Clarke   +35 more
core   +1 more source

Protein Amphipathic Helix Insertion: A Mechanism to Induce Membrane Fission

Frontiers in Cell and Developmental Biology, 2019
One of the fundamental features of biomembranes is the ability to fuse or to separate. These processes called respectively membrane fusion and fission are central in the homeostasis of events such as those related to intracellular membrane traffic ...
Mikhail A. Zhukovsky, Angela Filograna, Alberto Luini, Daniela Corda, Carmen Valente   +4 more
doaj   +1 more source

Reproductive Characteristic of Transgenic Massachusetts General Hospital Miniature Pigs for Xenotransplantation

Journal of Animal Reproduction and Biotechnology, 2017
Pigs have been extensively used as mediators of xenotransplantation research. Specifically, the Massachusetts General Hospital (MGH) miniature pig was developed to fix major histocompatibility antigens for use in xenotransplantation studies. We generated
Soo-Jeong Ji, Gunsup Lee, Sang Hyoun Park, Kyung Woon Kim, Sung-June Byun, Sun A Ock, Seongsoo Hwang, Jae-Seok Woo, Keon Bong Oh   +8 more
doaj   +1 more source

The M18 aspartyl aminopeptidase of Plasmodium falciparum binds to human erythrocyte spectrin in vitro

Malaria Journal, 2008
Background During erythrocytic schizogony, Plasmodium falciparum interacts with the human erythrocyte membrane when it enters into, grows within and escapes from the erythrocyte. An interaction between the P.
Coetzer Theresa L, Lauterbach Sonja B
doaj   +1 more source

Molecular Studies and an ex vivo Complement Assay on Endothelium Highlight the Genetic Complexity of Atypical Hemolytic Uremic Syndrome: The Case of a Pedigree With a Null CD46 Variant

Frontiers in Medicine, 2020
Atypical hemolytic uremic syndrome (aHUS) is an ultra-rare disease characterized by microangiopathic hemolysis, thrombocytopenia, and renal impairment and is associated with dysregulation of the alternative complement pathway on the microvascular ...
Rossella Piras, Paraskevas Iatropoulos, Elena Bresin, Marta Todeschini, Sara Gastoldi, Elisabetta Valoti, Marta Alberti, Caterina Mele, Miriam Galbusera, Paola Cuccarolo, Ariela Benigni, Giuseppe Remuzzi, Marina Noris   +12 more
doaj   +1 more source

Cooperation of decay-accelerating factor and membrane cofactor protein in regulating survival of human cervical cancer cells

BMC Cancer, 2009
Background Decay-accelerating factor (DAF) and membrane cofactor protein (MCP) are the key molecules involved in cell protection against autologus complement, which restricts the action of complement at critical stages of the cascade reaction.
Gong Hui, Su Ya-Juan, Gu Ping-Qing, Cai You-Qun, Guo Shu-Yu, Gao Ling-Juan, Liu Yun, Chen Chen   +7 more
doaj   +1 more source

TRIM25 Enhances the Antiviral Action of Zinc-Finger Antiviral Protein (ZAP). [PDF]

PLoS Pathogens, 2017
The host factor and interferon (IFN)-stimulated gene (ISG) product, zinc-finger antiviral protein (ZAP), inhibits a number of diverse viruses by usurping and intersecting with multiple cellular pathways. To elucidate its antiviral mechanism, we perform a
Melody M H Li, Zerlina Lau, Pamela Cheung, Eduardo G Aguilar, William M Schneider, Leonia Bozzacco, Henrik Molina, Eugen Buehler, Akinori Takaoka, Charles M Rice, Dan P Felsenfeld, Margaret R MacDonald   +11 more
doaj   +1 more source