Results 31 to 40 of about 104,326 (289)

Tissue factor residues that putatively interact with membrane phospholipids. [PDF]

PLoS ONE, 2014
Blood clotting is initiated by the two-subunit enzyme consisting of the plasma protease, factor VIIa (the catalytic subunit), bound to the integral membrane protein, tissue factor (the regulatory subunit).
Ke Ke, Jian Yuan, James H Morrissey
doaj   +1 more source

Various phenotypes of postpartum atypical hemolytic uremic syndrome: the role of genetic testing in determining prognosis. Case report

Терапевтический архив, 2023
We report a case of atypical hemolytic uremic syndrome (aHUS) that occurred after childbirth in a patient with a history of numerous recurrent episodes of TMA with nephrotic proteinuria and impaired renal function.
Tatiana V. Kirsanova, Alina I. Balakireva, Tatiana A. Fedorova, Aleksei V. Pyregov, Oleg V. Rogachevskiy   +4 more
doaj   +1 more source

Development of α 1,3-galactosyltransferase Inactivated and Human Membrane Cofactor Protein Expressing Homozygous Transgenic Pigs for Xenotransplantation

Journal of Animal Reproduction and Biotechnology, 2017
Transplantation is considered to be a very useful approach to improve human welfare and to prolong life-span. Heterologous organ transplantation using pig organs which are similar to human beings and easy to make mass-production has known as one of the ...
Gunsup Lee, Sang Hyoun Park, Haesun Lee, Soo-Jeong Ji, Joo Yung Lee, Sung-June Byun, Seongsoo Hwang, Kyung Woon Kim, Sun A Ock, Keon Bong Oh   +9 more
doaj   +1 more source

Implications of Membrane Binding by the Fe-S Cluster-Containing N-Terminal Domain in the Drosophila Mitochondrial Replicative DNA Helicase

Frontiers in Genetics, 2021
Recent evidence suggests that iron-sulfur clusters (ISCs) in DNA replicative proteins sense DNA-mediated charge transfer to modulate nuclear DNA replication.
Minyoung So, Johnny Stiban, Johnny Stiban, Grzegorz L. Ciesielski, Grzegorz L. Ciesielski, Grzegorz L. Ciesielski, Stacy L. Hovde, Laurie S. Kaguni, Laurie S. Kaguni   +8 more
doaj   +1 more source

Maturation of the cytochrome cd1 nitrite reductase NirS from Pseudomonas aeruginosa requires transient interactions between the three proteins NirS, NirN and NirF

Bioscience Reports, 2013
The periplasmic cytochrome cd1 nitrite reductase NirS occurring in denitrifying bacteria such as the human pathogen Pseudomonas aeruginosa contains the essential tetrapyrrole cofactors haem c and haem d1.
Tristan Nicke, Tobias Schnitzer, Karin Münch, Julia Adamczack, Kristin Haufschildt, Sabine Buchmeier, Martin Kucklick, Undine Felgenträger, Lothar Jänsch, Katharina Riedel, Gunhild Layer   +10 more
doaj   +1 more source

Conformational and mechanical stability of the isolated large subunit of membrane-bound [NiFe]-hydrogenase from Cupriavidus necator

Frontiers in Microbiology, 2023
Comprising at least a bipartite architecture, the large subunit of [NiFe]-hydrogenase harbors the catalytic nickel–iron site while the small subunit houses an array of electron-transferring Fe-S clusters.
Jovan Dragelj, Chara Karafoulidi-Retsou, Sagie Katz, Oliver Lenz, Ingo Zebger, Giorgio Caserta, Sophie Sacquin-Mora, Sophie Sacquin-Mora, Sophie Sacquin-Mora, Maria Andrea Mroginski   +9 more
doaj   +1 more source

Demonstration and characterization of CD46, membrane cofactor protein, in stomach.

Japanese Journal of Clinical Immunology, 1996
CD46, membrane cofactor protein, is a glycoprotein widely present on the cell membranes and is different in molecular weight among organs or cells in the same individual. It acts as a cofactor of I of the complement system, which inactivates C3b bound to the autologous cells, and protects them from the attack of the complement.
Seto, Nobuyuki, Takemura, Shuhei, Nakanishi, Sadanobu, Doi, Takashi, Ichio, Naoko, Nakahara, Risa, Kasamatsu, Yoshihiro, Yanagida, Kunio, Okamoto, Masayuki, Onodera, Hideki, Kondo, Motoharu   +10 more
openaire   +3 more sources

Atypical hemolytic uremic syndrome

Orphanet Journal of Rare Diseases, 2011
Hemolytic uremic syndrome (HUS) is defined by the triad of mechanical hemolytic anemia, thrombocytopenia and renal impairment. Atypical HUS (aHUS) defines non Shiga-toxin-HUS and even if some authors include secondary aHUS due to Streptococcus pneumoniae
Frémeaux-Bacchi Véronique, Loirat Chantal   +1 more
doaj   +1 more source

The tissue-specific Rep8/UBXD6 tethers p97 to the endoplasmic reticulum membrane for degradation of misfolded proteins.

PLoS ONE, 2011
The protein known as p97 or VCP in mammals and Cdc48 in yeast is a versatile ATPase complex involved in several biological functions including membrane fusion, protein folding, and activation of membrane-bound transcription factors.
Louise Madsen, Franziska Kriegenburg, Andrea Vala, Diana Best, Søren Prag, Kay Hofmann, Michael Seeger, Ian R Adams, Rasmus Hartmann-Petersen   +8 more
doaj   +1 more source

CD46 and Oncologic Interactions: Friendly Fire against Cancer

Antibodies, 2020
One of the most challenging aspects of cancer therapeutics is target selection. Recently, CD46 (membrane cofactor protein; MCP) has emerged as a key player in both malignant transformation as well as in cancer treatments.
Michelle Elvington, M. Kathryn Liszewski, John P. Atkinson   +2 more
doaj   +1 more source