Results 21 to 30 of about 104,326 (289)

Cells determine cell density using a small protein bound to a unique tissue-specific phospholipid [PDF]

PeerJ, 2013
Cell density is the critical parameter controlling tendon morphogenesis. Knowing its neighbors allows a cell to regulate correctly its proliferation and collagen production.
Christopher J. Petzold, Richard I. Schwarz   +1 more
doaj   +2 more sources

The small membrane protein CcoS is involved in cofactor insertion into the cbb3-type cytochrome c oxidase

Biochimica Et Biophysica Acta - Bioenergetics
Juna Rauch, Katharina Kurscheidt, Kefeng Shen, Andreea Andrei, Noel Daum, Yavuz Öztürk, Frédéric Melin, Gunhild Layer, Petra Hellwig, Fevzi Daldal, H Koch   +10 more
exaly   +2 more sources

A membrane‐bound [NiFe]‐hydrogenase large subunit precursor whose C‐terminal extension is not essential for cofactor incorporation but guarantees optimal maturation

MicrobiologyOpen, 2020
[NiFe]‐hydrogenases catalyze the reversible conversion of molecular hydrogen into protons end electrons. This reaction takes place at a NiFe(CN)2(CO) cofactor located in the large subunit of the bipartite hydrogenase module. The corresponding apo‐protein
Sven Hartmann, Stefan Frielingsdorf, Giorgio Caserta, Oliver Lenz   +3 more
doaj   +1 more source

Membrane cofactor protein of the complement system: alternative splicing of serine/threonine/proline-rich exons and cytoplasmic tails produces multiple isoforms that correlate with protein phenotype. [PDF]

Journal of Experimental Medicine, 1991
Liszewski M K, Atkinson J P
exaly   +2 more sources

Computational Analysis of CD46 Protein Interaction with SARS-CoV-2 Structural Proteins: Elucidating a Putative Viral Entry Mechanism into Human Cells

Viruses, 2023
This study examines an unexplored aspect of SARS-CoV-2 entry into host cells, which is widely understood to occur via the viral spike (S) protein’s interaction with human ACE2-associated proteins.
Pavel Vassiliev, Evgenii Gusev, Maria Komelkova, Andrey Kochetkov, Maria Dobrynina, Alexey Sarapultsev   +5 more
doaj   +1 more source

A unifying mechanism for the biogenesis of membrane proteins co-operatively integrated by the Sec and Tat pathways

eLife, 2017
The majority of multi-spanning membrane proteins are co-translationally inserted into the bilayer by the Sec pathway. An important subset of membrane proteins have globular, cofactor-containing extracytoplasmic domains requiring the dual action of the co-
Fiona J Tooke, Marion Babot, Govind Chandra, Grant Buchanan, Tracy Palmer   +4 more
doaj   +1 more source

Molecular cloning of a pig homologue of membrane cofactor protein (CD46) [PDF]

International Immunology, 1997
Organs of transgenic pigs that express human complement regulatory proteins are under assessment as an alternative to transplantation. A major barrier to the transplantation of pig organs is the hyperacute rejection caused by pre-existing antibodies and complement.
K, Toyomura, T, Fujimura, H, Murakami, T, Natsume, T, Shigehisa, N, Inoue, J, Takeda, T, Kinoshita   +7 more
openaire   +2 more sources

Membrane Cofactor Protein Is a Receptor for Adenoviruses Associated with Epidemic Keratoconjunctivitis [PDF]

Journal of Virology, 2004
ABSTRACT Subgroup D adenovirus (Ad) types 8, 19, and 37 (Ad8, -19, and -37, respectively) are causative agents of epidemic keratoconjunctivitis and genital tract infections. Previous studies showed that Ad37 binds to a 50-kDa membrane glycoprotein expressed on human ocular (conjunctival) cells. To identify and characterize the role of
Eugene, Wu, Sunia A, Trauger, Lars, Pache, Tina-Marie, Mullen, Daniel J, von Seggern, Gary, Siuzdak, Glen R, Nemerow   +6 more
openaire   +2 more sources

Cofactor-mediated conformational control in the bifunctional kinase/RNase Ire1

BMC Biology, 2011
Background Ire1 is a signal transduction protein in the endoplasmic reticulum (ER) membrane that serves to adjust the protein-folding capacity of the ER according to the needs of the cell.
Stroud Robert M, Finer-Moore Janet, Korostelev Andrei A, Egea Pascal F, Korennykh Alexei V, Zhang Chao, Shokat Kevan M, Walter Peter   +7 more
doaj   +1 more source

The Lamin B receptor is essential for cholesterol synthesis and perturbed by disease-causing mutations

eLife, 2016
Lamin B receptor (LBR) is a polytopic membrane protein residing in the inner nuclear membrane in association with the nuclear lamina. We demonstrate that human LBR is essential for cholesterol synthesis.
Pei-Ling Tsai, Chenguang Zhao, Elizabeth Turner, Christian Schlieker   +3 more
doaj   +1 more source