FRET-based Visualization of PDGF Receptor Activation at Membrane Microdomains [PDF]
Scientific Reports, 2017 Platelet-derived growth factor receptor (PDGFR) senses extracellular growth factors and transfer the signals inside the cells regulating cell proliferation, migration and survival.
Jihye Seong +4 more
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Analysis of acid-tolerance mechanism based on membrane microdomains in Saccharomyces cerevisiae [PDF]
Microbial Cell Factories, 2023 Background Saccharomyces cerevisiae has been used in the biosynthesis of acid products such as organic acids owing to its acid tolerance. Improving the acid tolerance of S. cerevisiae is beneficial for expanding its application range.
Xueqin Lv +9 more
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Structure and function of the membrane microdomains in osteoclasts [PDF]
Bone Research, 2023 The cell membrane structure is closely related to the occurrence and progression of many metabolic bone diseases observed in the clinic and is an important target to the development of therapeutic strategies for these diseases.
Jialong Hou +8 more
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Cardiac Hypertrophy Changes Compartmentation of cAMP in Non-Raft Membrane Microdomains [PDF]
Cells, 2021 3′,5′-Cyclic adenosine monophosphate (cAMP) is a ubiquitous second messenger which plays critical roles in cardiac function and disease. In adult mouse ventricular myocytes (AMVMs), several distinct functionally relevant microdomains with tightly ...
Nikoleta Pavlaki +4 more
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Glycolipids: Linchpins in the Organization and Function of Membrane Microdomains [PDF]
Frontiers in Cell and Developmental Biology, 2020 Membrane microdomains, also called lipid rafts, are areas on membrane enriched in glycolipids, sphingolipids, and cholesterol. Although membrane microdomains are thought to play key roles in many cellular functions, their structures, properties, and ...
Kei Hanafusa +3 more
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Structural Basis of the Interaction of the G Proteins, Gαi1, Gβ1γ2 and Gαi1β1γ2, with Membrane Microdomains and Their Relationship to Cell Localization and Activity [PDF]
Biomedicines, 2023 GPCRs receive signals from diverse messengers and activate G proteins that regulate downstream signaling effectors. Efficient signaling is achieved through the organization of these proteins in membranes.
Rafael Álvarez, Pablo V. Escribá
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Contributions of quantitative proteomics to understanding membrane microdomains [PDF]
Journal of Lipid Research, 2009 Membrane microdomains, e.g., lipid rafts and caveolae, are crucial cell surface organelles responsible for many cellular signaling and communication events, which makes the characterization of their proteomes both interesting and valuable. They are large
Yu Zi Zheng, Leonard J. Foster
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Plant Sterol Clustering Correlates with Membrane Microdomains as Revealed by Optical and Computational Microscopy [PDF]
Membranes, 2021 Local inhomogeneities in lipid composition play a crucial role in the regulation of signal transduction and membrane traffic. This is particularly the case for plant plasma membrane, which is enriched in specific lipids, such as free and conjugated forms
Ling Tang +4 more
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Plant Hormones Differentially Control the Sub-Cellular Localization of Plasma Membrane Microdomains during the Early Stage of Soybean Nodulation. [PDF]
Genes (Basel), 2019 Phytohormones regulate the mutualistic symbiotic interaction between legumes and rhizobia, nitrogen-fixing soil bacteria, notably by controlling the formation of the infection thread in the root hair (RH).
Qiao Z, Zogli P, Libault M.
europepmc +3 more sources
Localization of nuclear actin in nuclear lipid microdomains of liver and hepatoma cells: Possible involvement of sphingomyelin metabolism [PDF]
The EuroBiotech Journal, 2017 Nuclear actin has been implicated in different nuclear functions. In this work, its localization in nuclear membrane, chromatin and nuclear lipid microdomains was investigated. The implication of sphingomyelin metabolism was studied.
Cataldi Samuela +10 more
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