Analysis of acid-tolerance mechanism based on membrane microdomains in Saccharomyces cerevisiae [PDF]
Microbial Cell Factories, 2023 Background Saccharomyces cerevisiae has been used in the biosynthesis of acid products such as organic acids owing to its acid tolerance. Improving the acid tolerance of S. cerevisiae is beneficial for expanding its application range.
Xueqin Lv +9 more
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Structure and function of the membrane microdomains in osteoclasts [PDF]
Bone Research, 2023 The cell membrane structure is closely related to the occurrence and progression of many metabolic bone diseases observed in the clinic and is an important target to the development of therapeutic strategies for these diseases.
Jialong Hou +8 more
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Cardiac Hypertrophy Changes Compartmentation of cAMP in Non-Raft Membrane Microdomains [PDF]
Cells, 2021 3′,5′-Cyclic adenosine monophosphate (cAMP) is a ubiquitous second messenger which plays critical roles in cardiac function and disease. In adult mouse ventricular myocytes (AMVMs), several distinct functionally relevant microdomains with tightly ...
Nikoleta Pavlaki +4 more
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Glycolipids: Linchpins in the Organization and Function of Membrane Microdomains [PDF]
Frontiers in Cell and Developmental Biology, 2020 Membrane microdomains, also called lipid rafts, are areas on membrane enriched in glycolipids, sphingolipids, and cholesterol. Although membrane microdomains are thought to play key roles in many cellular functions, their structures, properties, and ...
Kei Hanafusa +3 more
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Host cell membrane microdomains and fungal infection. [PDF]
Cell Microbiol, 2021 Lipid microdomains or lipid rafts are dynamic and tightly ordered regions of the plasma membrane. In mammalian cells, they are enriched in cholesterol, glycosphingolipids, Glycosylphosphatidylinositol-anchored and signalling-related proteins. Several studies have suggested that mammalian pattern recognition receptors are concentrated or recruited to ...
Souza TN +6 more
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Structural Basis of the Interaction of the G Proteins, Gαi1, Gβ1γ2 and Gαi1β1γ2, with Membrane Microdomains and Their Relationship to Cell Localization and Activity [PDF]
Biomedicines, 2023 GPCRs receive signals from diverse messengers and activate G proteins that regulate downstream signaling effectors. Efficient signaling is achieved through the organization of these proteins in membranes.
Rafael Álvarez, Pablo V. Escribá
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Stepping between membrane microdomains. [PDF]
Biophys J, 2015 Lateral membrane microdomains are postulated to be involved in a number of important functions in mammalian cells, such as membrane trafficking, exocytosis, endocytosis, signal transduction, and protein activity (1,2). These putative cell microdomains have been the subject of extensive research using a variety of biophysical and biochemical techniques,
McIntosh TJ.
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Plant Sterol Clustering Correlates with Membrane Microdomains as Revealed by Optical and Computational Microscopy [PDF]
Membranes, 2021 Local inhomogeneities in lipid composition play a crucial role in the regulation of signal transduction and membrane traffic. This is particularly the case for plant plasma membrane, which is enriched in specific lipids, such as free and conjugated forms
Ling Tang +4 more
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Membrane microdomains: from seeing to understanding [PDF]
Frontiers in Plant Science, 2014 The plasma membrane is a composite material, which forms a semi-permeable barrier and an interface for communication between the intracellular and extracellular environments.
Binh-An eTruong Quang +1 more
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FRET-based Visualization of PDGF Receptor Activation at Membrane Microdomains [PDF]
Scientific Reports, 2017 Platelet-derived growth factor receptor (PDGFR) senses extracellular growth factors and transfer the signals inside the cells regulating cell proliferation, migration and survival.
Jihye Seong +4 more
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