Use of dansyl-cholestanol as a probe of cholesterol behavior in membranes of living cells[S]
Journal of Lipid Research, 2010 While plasma membrane cholesterol-rich microdomains play a role in cholesterol trafficking, little is known about the appearance and dynamics of cholesterol through these domains in living cells.
Huan Huang +5 more
doaj +1 more source
Initiation of hepatitis C virus infection is dependent on cholesterol and cooperativity between CD81 and scavenger receptor B type I. [PDF]
, 2006 In the past several years, a number of cellular proteins have been identified as candidate entry receptors for hepatitis C virus (HCV) by using surrogate models of HCV infection.
Barth, Heidi +4 more
core +2 more sources
Caveolin is present in intestinal cells: role in cholesterol trafficking?
Journal of Lipid Research, 1998 It was postulated that specialized microdomains of the plasma membrane, consistent with caveolae, might play a role in cholesterol trafficking in intestinal cells.
F. Jeffrey Field +3 more
doaj +1 more source
CR3 and Dectin-1 Collaborate in Macrophage Cytokine Response through Association on Lipid Rafts and Activation of Syk-JNK-AP-1 Pathway [PDF]
, 2015 Copyright: © 2015 Huang et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source ...
Brown, Gordon D +7 more
core +13 more sources
Alterations of membrane curvature during influenza virus budding [PDF]
, 2014 Influenza A virus belongs to the Orthomyxoviridae family. It is an enveloped virus that contains a segmented and negative-sense RNA genome. Influenza A viruses cause annual epidemics and occasional major pandemics, are a major cause of morbidity and ...
Agnieszka Martyna +29 more
core +1 more source
Loss of flotillin expression results in weakened desmosomal adhesion and Pemphigus vulgaris-like localisation of desmoglein-3 in human keratinocytes [PDF]
, 2016 Desmosomes are adhesion plaques that mediate cell-cell adhesion in many tissues, including the epidermis, and generate mechanical resistance to tissues. The extracellular domains of desmosomal cadherin proteins, desmogleins and desmocollins, are required
Ali, Jawahir +7 more
core +1 more source
Tracking microdomain dynamics in cell membranes
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2009 Studies of the diffusion of proteins and lipids in the plasma membrane of cells have long pointed to the presence of membrane domains. A major challenge in the field of membrane biology has been to characterize the various cellular structures and mechanisms that impede free diffusion in cell membranes and determine the consequences that membrane ...
Anne K. Kenworthy, Charles A. Day
openaire +3 more sources
Role of Membrane Microdomains in Compartmentation of cAMP Signaling [PDF]
PLoS ONE, 2014 Spatially restricting cAMP production to discrete subcellular locations permits selective regulation of specific functional responses. But exactly where and how cAMP signaling is confined is not fully understood. Different receptors and adenylyl cyclase isoforms responsible for cAMP production are not uniformly distributed between lipid raft and non ...
Agarwal, Shailesh R +7 more
openaire +8 more sources
The cytosolic N-terminus of CD317/tetherin is a membrane microdomain exclusion motif
Biology Open, 2013 Summary The integral membrane protein CD317/tetherin has been associated with a plethora of biological processes, including restriction of enveloped virus release, regulation of B cell growth, and organisation of membrane microdomains.
Peter G. Billcliff +3 more
doaj +1 more source
Host cell membrane microdomains and fungal infection [PDF]
Cellular Microbiology, 2021 Lipid microdomains or lipid rafts are dynamic and tightly ordered regions of the plasma membrane. In mammalian cells, they are enriched in cholesterol, glycosphingolipids, Glycosylphosphatidylinositol-anchored and signalling-related proteins. Several studies have suggested that mammalian pattern recognition receptors are concentrated or recruited to ...
Taiane N. Souza +6 more
openaire +3 more sources