Results 41 to 50 of about 29,208 (221)

Membrane-Sculpting BAR Domains Generate Stable Lipid Microdomains

Cell Reports, 2013
Bin-Amphiphysin-Rvs (BAR) domain proteins are central regulators of many cellular processes involving membrane dynamics. BAR domains sculpt phosphoinositide-rich membranes to generate membrane protrusions or invaginations.
Hongxia Zhao, Alphée Michelot, Essi V. Koskela, Vadym Tkach, Dimitrios Stamou, David G. Drubin, Pekka Lappalainen   +6 more
doaj   +1 more source

Animal Cell Cytokinesis: The Rho-Dependent Actomyosin-Anilloseptin Contractile Ring as a Membrane Microdomain Gathering, Compressing, and Sorting Machine

Frontiers in Cell and Developmental Biology, 2020
Cytokinesis is the last step of cell division that partitions the cellular organelles and cytoplasm of one cell into two. In animal cells, cytokinesis requires Rho-GTPase-dependent assembly of F-actin and myosin II (actomyosin) to form an equatorial ...
Sabrya C. Carim, Amel Kechad, Gilles R. X. Hickson, Gilles R. X. Hickson   +3 more
doaj   +1 more source

Membrane microdomains and cAMP compartmentation

The FASEB Journal, 2012
The role of different membrane domains in the compartmentation of cAMP signaling was investigated using the FRET‐based Epac2‐ camps biosensor. The MyrPalm sequence from Lyn kinase and the CAAX sequence from Rho GTPase were used to target this probe to lipid raft (Epac2‐MyrPalm) or non‐lipid raft (Epac2‐CAAX) membrane domains in HEK293 cells.
Shailesh Agarwal, Kacie Caldwell, Ashley Owens, Cherie Singer, Viacheslav Nikolaev, Martin Lohse, Robert Harvey   +6 more
openaire   +1 more source

CD317/Tetherin is an organiser of membrane microdomains [PDF]

Journal of Cell Science, 2013
The integral membrane protein tetherin has been associated with an eclectic mix of cellular processes, including restricting the release of a range of enveloped viruses from infected cells. The unusual topology of tetherin (it possesses both a conventional transmembrane domain and a glycosylphosphatidylinositol anchor), its localisation to membrane ...
Billcliff, Peter G., Rollason, Ruth, Prior, Ian, Owen, Dylan M., Gaus, Katharina, Banting, George   +5 more
openaire   +3 more sources

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Electroactive Liquid Crystal Elastomers as Soft Actuators

Advanced Functional Materials, EarlyView.
Electroactive liquid crystal elastomers (eLCEs) can be actuated via electromechanical, electrochemical, or electrothermal effects. a) Electromechanical effects include Maxwell stress, electrostriction, and the electroclinic effect. b) Electrochemical effects arise from electrode redox reactions.
Yakui Deng, Min‐Hui Li
wiley   +1 more source

Fatty Acyl Coenzyme A Synthetase Fat1p Regulates Vacuolar Structure and Stationary-Phase Lipophagy in Saccharomyces cerevisiae

Microbiology Spectrum, 2023
During yeast stationary phase, a single spherical vacuole (lysosome) is created by the fusion of several small ones. Moreover, the vacuolar membrane is reconstructed into two distinct microdomains.
Fan Qiu, Na Kang, Jinling Tan, Sisi Yan, Leiying Lin, Lipeng Cai, Joel M. Goodman, Qiang Gao   +7 more
doaj   +1 more source

Adenosine receptors and membrane microdomains

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2011
Adenosine receptors are a member of the large family of seven transmembrane spanning G protein coupled receptors. The four adenosine receptor subtypes-A(1), A(2a), A(2b), A(3)-exert their effects via the activation of one or more heterotrimeric G proteins resulting in the modulation of intracellular signaling. Numerous studies over the past decade have
openaire   +2 more sources

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

Localization of nuclear actin in nuclear lipid microdomains of liver and hepatoma cells: Possible involvement of sphingomyelin metabolism

The EuroBiotech Journal, 2017
Nuclear actin has been implicated in different nuclear functions. In this work, its localization in nuclear membrane, chromatin and nuclear lipid microdomains was investigated. The implication of sphingomyelin metabolism was studied.
Cataldi Samuela, Lazzarini Andrea, Codini Michela, Cascianelli Giacomo, Floridi Alessandro, Bartoccini Elisa, Ceccarini Maria Rachele, Ambesi-Impiombato Francesco Saverio, Beccari Tommaso, Curcio Francesco, Albi Elisabetta   +10 more
doaj   +1 more source