Results 31 to 40 of about 26,711 (229)
Insights into the function of ESCRT and its role in enveloped virus infection
Frontiers in Microbiology, 2023 The endosomal sorting complex required for transport (ESCRT) is an essential molecular machinery in eukaryotic cells that facilitates the invagination of endosomal membranes, leading to the formation of multivesicular bodies (MVBs).
Chunxuan Wang +5 more
doaj +1 more source
Shear-Driven Instabilities of Membrane Tubes and Dynamin-Induced Scission [PDF]
Physical Review Letters, 2020 Main Text: 5 pages, 3 figures + S.I. 14 pages, 6 figures (Accepted Version)
Sami C. Al-Izzi +2 more
openaire +4 more sources
A feedback loop between dynamin and actin recruitment during clathrin-mediated endocytosis.
PLoS Biology, 2012 Clathrin-mediated endocytosis proceeds by a sequential series of reactions catalyzed by discrete sets of protein machinery. The final reaction in clathrin-mediated endocytosis is membrane scission, which is mediated by the large guanosine triophosphate ...
Marcus J Taylor +2 more
doaj +1 more source
Alterations of membrane curvature during influenza virus budding [PDF]
, 2014 Influenza A virus belongs to the Orthomyxoviridae family. It is an enveloped virus that contains a segmented and negative-sense RNA genome. Influenza A viruses cause annual epidemics and occasional major pandemics, are a major cause of morbidity and ...
Agnieszka Martyna +29 more
core +1 more source
Crucial Role for Membrane Fluidity in Proliferation of Primitive Cells
Cell Reports, 2012 The cell wall is a defining structural feature of the bacterial subkingdom. However, most bacteria are capable of mutating into a cell-wall-deficient “L-form” state, requiring remarkable physiological and structural adaptations. L-forms proliferate by an
Romain Mercier +2 more
doaj +1 more source
Experimental study of the effects of hypochlorite on polysulfone membrane properties [PDF]
, 2006 Although chemical solutions are widely employed to clean membranes, they can also be responsible for changes in membrane properties. The two major drawbacks are then either the functional properties of the membrane gradually change, so the production can
Aimar, Pierre +2 more
core +2 more sources
Regulation of membrane scission in yeast endocytosis
, 2021 AbstractDuring clathrin-mediated endocytosis, a flat plasma membrane is shaped into an invagination that undergoes scission to form a vesicle. In mammalian cells, the force that drives the transition from invagination to vesicle is primarily provided by the GTPase dynamin that acts in concert with crescent-shaped BAR domain proteins.
Deepikaa Menon, Marko Kaksonen
openaire +2 more sources
CryoEM structure of the super-constricted two-start dynamin 1 filament
Nature Communications, 2021 Dynamin mediates the fission of vesicles during endocytosis. Here, the authors report the cryoEM structure of a super-constricted two-start dynamin 1 filament- one of the two known helical forms of dynamin, with insights into the molecular mechanisms of ...
Jiwei Liu +4 more
doaj +1 more source
Influenza virus M2 protein mediates ESCRT-independent membrane scission. [PDF]
Cell, 2010 Many viruses utilize host ESCRT proteins for budding; however, influenza virus budding is thought to be ESCRT-independent. In this study we have found a role for the influenza virus M2 proton-selective ion channel protein in mediating virus budding. We observed that a highly conserved amphipathic helix located within the M2 cytoplasmic tail mediates a ...
Rossman JS, Jing X, Leser GP, Lamb RA.
europepmc +4 more sources
Dynamin recruitment by clathrin coats: a physical step? [PDF]
, 2003 Recent structural findings have shown that dynamin, a cytosol protein playing a key-role in clathrin-mediated endocytosis, inserts partly within the lipid bilayer and tends to self-assemble around lipid tubules. Taking into account these observations, we
Dommersnes, P. -G. +2 more
core +2 more sources