Altered brain energetics induces mitochondrial fission arrest in Alzheimer's Disease. [PDF]
, 2016 Altered brain metabolism is associated with progression of Alzheimer's Disease (AD). Mitochondria respond to bioenergetic changes by continuous fission and fusion.
Bachmeier, Benjamin V +15 more
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Structure and function of bacterial dynamin-like proteins [PDF]
, 2012 Membrane dynamics are essential for numerous cellular processes in eukaryotic and prokaryotic cells. In eukaryotic cells, membrane fusion and fission are often catalyzed by large GTPases of the dynamin protein family. These proteins couple GTP hydrolysis
Bramkamp, Marc
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Fusion and scission of membranes: Ubiquitous topological transformations in cells [PDF]
Traffic, 2017 The 2016 Nobel Prizes were awarded to Yoshinori Ohsumi for autophagy and to David Thouless, Duncan Haldane and Michael Kosterlitz for topological transitions. Both of these phenomena are intrinsically related when it comes to membranes. Here, we give a brief account on topological transformations of lipid membranes, commonly known as membrane fusion ...
Knorr, R., Mizushima, N., Dimova, R.
openaire +4 more sources
The mechanochemistry of endocytosis. [PDF]
PLoS Biology, 2009 Endocytic vesicle formation is a complex process that couples sequential protein recruitment and lipid modifications with dramatic shape transformations of the plasma membrane. Although individual molecular players have been studied intensively, how they
Jian Liu +3 more
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Loss of PIKfyve Causes Transdifferentiation of Dictyostelium Spores Into Basal Disc Cells
Frontiers in Cell and Developmental Biology, 2021 The 1-phosphatidylinositol-3-phosphate 5-kinase PIKfyve generates PtdIns3,5P2 on late phagolysosomes, which by recruiting the scission protein Atg18, results in their fragmentation in the normal course of endosome processing.
Yoko Yamada +6 more
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Animal cell cytokinesis: the role of dynamic changes in the plasma membrane proteome and lipidome [PDF]
, 2016 In animal cells, cytokinesis is characterised by the formation of the mitotic spindle that signals the assembly of an actomyosin ring between the spindle poles.
Gould, Gwyn W.
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ESCRT-III mediated cell division in Sulfolobus acidocaldarius - a reconstitution perspective [PDF]
, 2014 In the framework of synthetic biology, it has become an intriguing question what would be the minimal representation of cell division machinery. Thus, it seems appropriate to compare how cell division is realized in different microorganisms. Inparticular,
Härtel, T., Schwille, P.
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The Toxoplasma gondii active serine hydrolase 4 regulates parasite division and intravacuolar parasite architecture [PDF]
, 2018 Hydrolase are enzymes that regulate diverse biological processes, including posttranslational protein modifications. Recent work identified four active serine hydrolases (ASHs) in Toxoplasma gondii as candidate depalmitoylases. However, only TgPPT1 (ASH1)
Amara, Neri +7 more
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Cell Reports, 2017 Clathrin/adaptor protein-1-coated carriers connect the secretory and the endocytic pathways. Carrier biogenesis relies on distinct protein networks changing membrane shape at the trans-Golgi network, each regulating coat assembly, F-actin-based ...
Mihaela Anitei +10 more
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The role of traction in membrane curvature generation. [PDF]
, 2018 Curvature of biological membranes can be generated by a variety of molecular mechanisms including protein scaffolding, compositional heterogeneity, and cytoskeletal forces.
Alimohamadi, H +4 more
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