The AFF-1 exoplasmic fusogen is required for endocytic scission and seamless tube elongation
Nature Communications, 2018 Membrane fusion and fission events at exoplasmic membrane surfaces are not well understood. Here the authors show that the C. elegans cell–cell fusogen AFF-1 is required for endocytic scission and apically-directed membrane trafficking during the ...
Fabien Soulavie +2 more
doaj +1 more source
Stepwise remodeling and subcompartment formation in individual vesicles by three ESCRT-III proteins
iScience, 2023 Summary: The endosomal sorting complex required for transport (ESCRT) is a multi-protein machinery involved in several membrane remodeling processes. Different approaches have been used to resolve how ESCRT proteins scission membranes.
Yunuen Avalos-Padilla +6 more
doaj +1 more source
ESCRT-III-dependent and -independent egress of herpesviruses
Frontiers in VirologyEnveloped viruses complete their replication cycle by forming virions that bud from infected cells through membrane scission. The mechanisms by which this is achieved are less well-understood than the well-characterized membrane scission of vesicles ...
Jun Arii
doaj +1 more source
A noncanonical role for dynamin-1 in regulating early stages of clathrin-mediated endocytosis in non-neuronal cells. [PDF]
PLoS Biology, 2018 Dynamin Guanosine Triphosphate hydrolases (GTPases) are best studied for their role in the terminal membrane fission process of clathrin-mediated endocytosis (CME), but they have also been proposed to regulate earlier stages of CME.
Saipraveen Srinivasan +7 more
doaj +1 more source
A PX-BAR protein Mvp1/SNX8 and a dynamin-like GTPase Vps1 drive endosomal recycling
eLife, 2021 Membrane protein recycling systems are essential for maintenance of the endosome-lysosome system. In yeast, retromer and Snx4 coat complexes are recruited to the endosomal surface, where they recognize cargos. They sort cargo and deform the membrane into
Sho W Suzuki +5 more
doaj +1 more source
Assembly and disassembly of the ESCRT-III membrane scission complex.
FEBS Lett, 2011 The ESCRT (endosomal sorting complex required for transport) pathway promotes the final membrane scission step at the end of cytokinesis, assists viral budding and generates multivesicular bodies (MVBs). These seemingly unrelated processes require a topologically similar membrane deformation and scission event that buds membranes/vesicles out of the ...
Adell MA, Teis D.
europepmc +4 more sources
Thermal decomposition of a honeycomb-network sheet - A Molecular Dynamics simulation study
, 2012 The thermal degradation of a graphene-like two-dimensional triangular membrane with bonds undergoing temperature-induced scission is studied by means of Molecular Dynamics simulation using Langevin thermostat.
A. Milchev +4 more
core +1 more source
ER-mitochondria contacts: Actin dynamics at the ER control mitochondrial fission via calcium release. [PDF]
, 2017 The formin-like protein INF2 is an important player in the polymerization of actin filaments. In this issue, Chakrabarti et al. (2018. J. Cell Biol.
Koehler, Carla M, Steffen, Janos
core +1 more source
Membrane deformation and scission by the HSV-1 nuclear egress complex [PDF]
Nature Communications, 2014 The nuclear egress complex (NEC) of herpesviruses such as HSV-1 is essential for the exit of nascent capsids from the cell nucleus. The NEC drives nuclear envelope vesiculation in cells, but the precise budding mechanism and the potential involvement of cellular proteins are unclear.
Bigalke, Janna M. +3 more
openaire +2 more sources
Non-equilibrium raft-like membrane domains under continuous recycling
, 2005 We present a model for the kinetics of spontaneous membrane domain (raft) assembly that includes the effect of membrane recycling ubiquitous in living cells.
A. Filippov +10 more
core +1 more source