Results 11 to 20 of about 232,617 (246)
Membrane Trafficking During Plant Cytokinesis [PDF]
Traffic, 2002 Plant morphogenesis is regulated by cell division and expansion. Cytokinesis, the final stage of cell division, culminates in the construction of the cell plate, a unique cytokinetic membranous organelle that is assembled across the inside of the dividing cell.
Sebastian Y, Bednarek, Tanya G, Falbel
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STAR Protocols, 2020 Summary: Lysosomes are dynamic organelles that serve as regulatory hubs in cellular homeostasis. Changes in lysosome morphology, composition, and turnover are typically linked to disease.
Arun Kumar Tharkeshwar +2 more
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BMC Biology, 2017 Background In a macro-molecular complex, any minor change may prove detrimental. For a supra-molecular nano-machine like the bacterial flagellum, which consists of several distinct parts with specific characteristics, stability is important.
Clive S. Barker +4 more
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Targeting Membrane Trafficking as a Strategy for Cancer Treatment
Vaccines, 2022 Membrane trafficking is emerging as an attractive therapeutic strategy for cancer. Recent reports have found a connection between Wnt signaling, receptor-mediated endocytosis, V-ATPase, lysosomal activity, and macropinocytosis through the canonical Wnt ...
Nydia Tejeda-Muñoz +3 more
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eLife, 2020 γ-Secretase is a multi-subunit enzyme whose aberrant activity is associated with Alzheimer’s disease and cancer. While its structure is atomically resolved, γ-secretase localization in the membrane in situ relies mostly on biochemical data.
Abril Angélica Escamilla-Ayala +12 more
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Complete structure of the bacterial flagellar hook reveals extensive set of stabilizing interactions
Nature Communications, 2016 The bacterial flagellar hook is made up of many copies of the protein FlgE. Here, the authors report the full structure of the hook from Campylobacter jejuni and show that its overall structure is different from that of the previously published filament.
Hideyuki Matsunami +4 more
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Biochemical and structural insights into Rab12 interactions with RILP and its family members
Scientific Reports, 2021 Alongside its biosynthetic functions, the small GTPase Rab12 negatively regulates mast cell (MC) exocytosis by its interaction with RILP to promote retrograde transport of the MC secretory granules.
Jana Omar +7 more
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F1000Research, 2020 Melanin pigments are responsible for human skin and hair color, and they protect the body from harmful ultraviolet light. The black and brown melanin pigments are synthesized in specialized lysosome-related organelles called melanosomes in melanocytes ...
Norihiko Ohbayashi, Mitsunori Fukuda
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Cells, 2022 In obesity, chronic membrane-localization of CD36 free fatty acid (FFA) translocase, but not other FFA transporters, enhances FFA uptake and intracellular lipid accumulation.
Nicole K. Nakamura +3 more
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Membrane Trafficking in Plant Immunity [PDF]
Molecular Plant, 2017 Plants employ sophisticated mechanisms to interact with pathogenic as well as beneficial microbes. Of those, membrane trafficking is key in establishing a rapid and precise response. Upon interaction with pathogenic microbes, surface-localized immune receptors undergo endocytosis for signal transduction and activity regulation while cell wall ...
Gu, Yangnan +2 more
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