Results 221 to 230 of about 95,337 (328)

Immune cells and the risk of acne vulgaris: A Mendelian randomization study. [PDF]

Medicine (Baltimore)
Yang X, Wu W, Yang J.
europepmc   +1 more source

Integrated biomarker landscape for the early detection and management of calcific aortic valve disease

European Journal of Clinical Investigation, EarlyView.
Calcific aortic valve disease (CAVD), the leading valvular disorder in older adults, progresses from sclerosis to severe stenosis without effective medical therapies, making early non‐invasive detection essential. Circulating and mechanistic biomarkers reflect core pathogenic axes, including lipid oxidation, inflammation, mineral metabolism ...
Alberto Cook‐Calvete, Silvia Moreta, Maria Delgado‐Marin, Blanca Fernandez‐Rodriguez, Carlos Zaragoza, Marta Saura   +5 more
wiley   +1 more source

No causal links between estradiol and female's brain and mental health using Mendelian randomization. [PDF]

Nat Commun
Oppenheimer H, van der Meer D, Schindler LS, Crestol A, Shadrin A, Andreassen OA, Westlye LT, de Lange AG, Barth C.   +8 more
europepmc   +1 more source

Mendelian randomization analysis

Mendelian randomization ...
openaire   +1 more source

Assessment of intrathecal therapy in the treatment of familial haemophagocytic lymphohistiocytosis

British Journal of Haematology, EarlyView.
Katarina Zivkovic, Elisabet Bergsten, Maurizio Aricó, Itziar Astigarraga, Eiichi Ishii, Stephan Ladisch, Kai Lehmberg, Milen Minkov, Vasanta Nanduri, Jan‐Inge Henter   +9 more
wiley   +1 more source

IL‐6 in the spotlight: From cardiovascular pathophysiology to therapy

European Journal of Clinical Investigation, EarlyView.
Interleukin‐6 (IL‐6) links inflammation to cardiovascular and multi‐organ dysfunction. This review integrates mechanistic, translational, and clinical evidence supporting IL‐6 as both a biomarker and therapeutic target in the continuum of cardiovascular and cardio‐renal disease.
Alberto Preda, Amedeo Tirandi, Giulio Leo, Davide Di Vece, Gemma Vilahur, Aldo Bonaventura, Elena Osto, Stefano Ministrini, Simon Kraler, Petra Kleinbogard, Giovanni Camici, Federico Carbone, Fabrizio Montecucco, Luca Liberale   +13 more
wiley   +1 more source

Identification of COVID-19 susceptibility genes by Mendelian randomization. [PDF]

Sci Prog
Wang H, Ma K, Wu J, Shan M, Zhang G.
europepmc   +1 more source

Intersections of vitamin D deficiency, HIV and chronic liver diseases

HIV Medicine, EarlyView.
Abstract Objectives Despite effective antiretroviral therapy (ART), chronic liver diseases remain a leading cause of morbidity and mortality among people with HIV, with metabolic dysfunction–associated steatotic liver disease (MASLD) now the predominant etiology. Vitamin D deficiency is also highly prevalent in this population.
Francesca Farina, Aurgho Datta, Suzanne N. Morin, Sahar Saeed, Bertrand Lebouche, Giovanni Guaraldi, Salvatore Petta, Giada Sebastiani   +7 more
wiley   +1 more source

Relationship Between Gut Microbiota and Phenylalanine Levels: A Mendelian Randomization Study. [PDF]

Microbiologyopen
Liu Z, Ye M, Jin H, Chen W, Jieens H, Han R.   +5 more
europepmc   +1 more source

Causal relationship between genetically predicted mental disorders and frailty: a bidirectional and multivariable mendelian randomization study [PDF]

Wenxi Sun, Ping Sun, Sijia Tang, Xiaohui Wu, Jun Chen, Yiru Fang, Xiaobin Zhang   +6 more
openalex   +1 more source