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The Role of Meningeal Lymphatic Systems

The meningeal lymphatic system is a newly identified network of lymphatic vessels located within the meninges, the protective membranes enveloping the brain and spinal cord. This system is essential for clearing waste products, supporting immune responses, and ensuring the balance of brain functions.
Gaiqing Wang   +5 more
openaire   +1 more source

Emerging Roles of Meningeal Lymphatic Vessels in Ischemic Stroke

Molecular Neurobiology
This review highlights the emerging relevance of meningeal lymphatic vessels (MLVs) in the context of ischemic stroke, challenging the conventional view of a privileged immunological central nervous system. MLVs facilitate immunological surveillance by modulating the entry of peripheral immune cells into the meningeal compartment, a process not impeded
Richard Simon, Machado   +7 more
openaire   +2 more sources

Effect Factors of Meningeal Lymphatics (MLVs)

The regulatory mechanism for meningeal lymphatics is not fully understood yet, but research is ongoing to uncover its functions and regulation. Several factors play a role in regulating these vessels, including: Circadian Rhythm: There is evidence suggesting that MLVs exhibit circadian rhythms in their function.
Gaiqing Wang   +5 more
openaire   +1 more source

The glymphatic system and meningeal lymphatics of the brain: new understanding of brain clearance

Reviews in the Neurosciences, 2021
O B Bogomyakova, Galina Valova
exaly  

Demonstration of chemotherapeutic mediated lymphatic changes in meningeal lymphatics in vitro, ex vivo, and in vivo

Abstract Systemic chemotherapeutics target cancer cells but are also known to impact other cells away from the tumor. Questions remain whether systemic chemotherapy crosses the blood-brain barrier and causes inflammation in the periphery that impacts the central nervous system (CNS) downstream.
L. Monet Roberts   +6 more
openaire   +2 more sources

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