Results 161 to 170 of about 16,979 (233)

Reconstituted ferredoxin-MEP pathway of Apicomplexa in Escherichiacoli as an in situ screening platform for inhibitors and essential enzyme mutations. [PDF]

J Biol Chem
Akuh OA, Maus D, Blume M, Saliba KJ, Seeber F.   +4 more
europepmc   +1 more source

The organ-specific differential roles of rice DXS and DXR, the first two enzymes of the MEP pathway, in carotenoid metabolism in Oryza sativa leaves and seeds. [PDF]

BMC Plant Biol, 2020
You MK, Lee YJ, Kim JK, Baek SA, Jeon YA, Lim SH, Ha SH.   +6 more
europepmc   +1 more source

Screening Inhibitors of Methylerythritol Phosphate (MEP) Pathway Enzymes

, 2017
With various antibiotics becoming illegitimate due to bacteria building up resistance to them, it becomes imperative to find new antibiotics to replace the ones that no longer work.
Gaspari, Brittany M.
core  

USP5‐C‐MAF Axis Regulates Autophagy‐Dependent Neuronal Ferroptosis in Spinal Cord Injury Therapeutics

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
SCI induces significant upregulation of USP5 in neurons. The overexpressed USP5 stabilizes c‐MAF protein expression through its deubiquitinase activity, activating autophagy and accelerating the degradation of autophagic ferritin, thereby mediating neuronal ferroptosis. This ultimately leads to impaired functional recovery in SCI mice.
Shiyang Weng, Kai Wu, Yinjun Huang, Lei Cao, Huichao Fu   +4 more
wiley   +1 more source

NbHDR, A Host Protein Involved in the MEP Pathway, Interacts With Bamboo Mosaic Virus Replicase and Enhances Viral Accumulation. [PDF]

Mol Plant Pathol
Wong CH, Hu CC, Tsai CH, Lin NS, Hsu YH, Lin MK, Huang YW.   +6 more
europepmc   +1 more source

Bibliometric Analysis of Cubebenes and Related Sesquiterpenes: Natural Occurrence, Biosynthesis, Pharmacological Activities, and In‐Silico‐Based Future Therapeutic Potential

eFood, Volume 7, Issue 3, June 2026.
Cubebene‐related sesquiterpenes, found across diverse biological sources, exhibit promising pharmacological activities, including anti‐inflammatory, neuroprotective, and anticancer effects. This review highlights their molecular diversity, ADME profiles, and predicted multitarget interactions, underscoring their therapeutic relevance and potential in ...
Khadija Boualam, Ahmet B. Ortaakarsu, Sohaib Khatib, Mohamed A. Farag, Mansour Sobeh   +4 more
wiley   +1 more source

The chromosome-scale genomes of two Tinospora species reveal differential regulation of the MEP pathway in terpenoid biosynthesis. [PDF]

BMC Biol
Chen Z, Xun L, Lu Y, Yang X, Chen M, Yang T, Mei Z, Yang Y, Yang X, Yang Y.   +9 more
europepmc   +1 more source

Synthesis of molecular tools for the study of enzymes from the MEP pathway

La voie du MEP permet la biosynthèse des isoprénoïdes dans la majorité des bactéries pathogènes, les parasites Apicomplexa et les plastides des cellules végétales chlorophylliennes.
Simonet, Basile
core  

Antimalarial Drug Discovery: Exploring the MEP Pathway [PDF]

, 2017
openaire   +1 more source

What Could Have Been: Predicted and Actual Exclusion by Potential Romantic Partners and Platonic Friends

European Journal of Social Psychology, Volume 56, Issue 4, Page 674-690, June 2026.
ABSTRACT Romantic partners are instrumental to more goals than friends, and therefore, people have more to lose when denied a romantic relationship than a friendship. We explored people's forecasted and experienced rejection by a potential romantic partner or friend.
Natasha R. Wood, Sydney G. Wicks, Adam J. Beam, Elijah P. Mudryk, Ellie Bray, Andrew H. Hales   +5 more
wiley   +1 more source