Results 181 to 190 of about 3,014,380 (256)

Metabolic engineering of endogenous MEP pathway for enhanced lycopene production in <i>Escherichia coli</i>. [PDF]

Synth Syst Biotechnol
Xu X, Xing H, Zhi H, Qin C, Deng Y, Wei W, Huang C.   +6 more
europepmc   +1 more source

Losartan API and Nitrosamines Impurities—Stability Profile Investigation Using HPLC, LC‐MS, and In Silico Assessment

Journal of Separation Science, Volume 49, Issue 5, May 2026.
ABSTRACT Nitrosamines are potent genotoxic impurities with well reported mutagenic and carcinogenic effects. Their presence has been detected in several pharmaceutical products among them losartan, an angiotensin II receptor blocker. Considering the risks already reported for these impurities, the present study aimed to investigate the influence of ...
Paulo Roberto Rodrigues Martini, Lilian Fanfa Machioli, Bruno Pereira dos Santos, Tiago Franco de Oliveira, Fávero Reisdorfer Paula, Clésio Soldateli Paim, Andreas Sebastian Loureiro Mendez   +6 more
wiley   +1 more source

MEP Pathway: First-Synthesized IspH-Directed Prodrugs with Potent Antimycobacterial Activity. [PDF]

Microorganisms
Allamand A, Noël-Duchesneau L, Ettelbruck C, De Luna E, Lièvremont D, Grosdemange-Billiard C.   +5 more
europepmc   +1 more source

Antimalarial Drug Discovery: Exploring the MEP Pathway [PDF]

, 2017
openaire   +1 more source

Placental‐Derived Connective Tissue Matrix Mediates Murine Recurrent Laryngeal Nerve Regeneration

The Laryngoscope, Volume 136, Issue 5, Page 2220-2231, May 2026.
Placentally derived connective tissue matrix (pd‐CTM) innately contains various neurotrophic, angiogenic, anti‐inflammatory, and tissue remodeling cytokines. In this mouse model of unilateral vocal fold paralysis, we investigate its effects on recurrent laryngeal nerve (RLN) regeneration and reinnervation of the right thyroarytenoid (TA) muscle after ...
Sunjay Anekal, Ananya Tadikonda, Gabriel Sobczak, Lena W. Chen, Aditya Bhatt, Troy Wesson, Patrick R. Finnegan, Stacey Halum   +7 more
wiley   +1 more source

Reconstituted ferredoxin-MEP pathway of Apicomplexa in Escherichiacoli as an in situ screening platform for inhibitors and essential enzyme mutations. [PDF]

J Biol Chem
Akuh OA, Maus D, Blume M, Saliba KJ, Seeber F.   +4 more
europepmc   +1 more source

Insights Into Bifenthrin Stereoisomers and Their Regulatory Implications

ChemistryOpen, Volume 15, Issue 5, May 2026.
Bifenthrin is a pyrethroid insecticide with two stereogenic centers, generating four stereoisomers with distinct physicochemical and electronic properties. A combined crystallographic and density functional theory study, supported by Hirshfeld surface, quantum theory of atoms in molecules, natural bond orbital, and reactivity descriptor analyses ...
Nayara C. M. Santos, Nayara D. Coutinho, Vitor S. Duarte, Anderson Catao, Antônio S. N. Aguiar, Lucas D. Dias, James O. Fajemiroye, Hamilton B. Napolitano   +7 more
wiley   +1 more source

NbHDR, A Host Protein Involved in the MEP Pathway, Interacts With Bamboo Mosaic Virus Replicase and Enhances Viral Accumulation. [PDF]

Mol Plant Pathol
Wong CH, Hu CC, Tsai CH, Lin NS, Hsu YH, Lin MK, Huang YW.   +6 more
europepmc   +1 more source

Patterns and Clinical Efficacy of Biologics Switching in Patients With Severe Asthma: A Systematic Review and Meta‐Analysis

Allergy, Volume 81, Issue 5, Page 1548-1570, May 2026.
This meta‐analysis included 2292 patients with severe asthma who underwent biologic switching across 23 countries/regions. The most prevalent switching pattern was from mepolizumab to benralizumab, with suboptimal asthma control being the primary reason.
Yang Zheng, Ya‐chun Li, Sheng‐jie Li, Meng Xu, Jia‐qian Hu, Wen‐qu Tian, Shi‐wei Chen, Xue‐hui Li, Ying He, Gan Lu, Mübeccel Akdis, Ioana Agache, Cezmi A. Akdis, Ya‐dong Gao   +13 more
wiley   +1 more source

The chromosome-scale genomes of two Tinospora species reveal differential regulation of the MEP pathway in terpenoid biosynthesis. [PDF]

BMC Biol
Chen Z, Xun L, Lu Y, Yang X, Chen M, Yang T, Mei Z, Yang Y, Yang X, Yang Y.   +9 more
europepmc   +1 more source