Results 81 to 90 of about 16,979 (233)

Functional replacement of isoprenoid pathways in Rhodobacter sphaeroides

Microbial Biotechnology, 2020
Summary Advances in synthetic biology and metabolic engineering have proven the potential of introducing metabolic by‐passes within cell factories.
Enrico Orsi, Jules Beekwilder, Dewi vanGelder, Adèle vanHouwelingen, Gerrit Eggink, Servé W.M. Kengen, Ruud A. Weusthuis   +6 more
doaj   +1 more source

Increasing diterpene yield with a modular metabolic engineering system in E. coli: comparison of MEV and MEP isoprenoid precursor pathway engineering [PDF]

, 2009
Engineering biosynthetic pathways in heterologous microbial host organisms offers an elegant approach to pathway elucidation via the incorporation of putative biosynthetic enzymes and characterization of resulting novel metabolites.
Hershey, David M., Lowry, Luke, Mara K. Determan, Meimei Xu, Xu, Meimei, Peters, Reuben J., Dana Morrone, Luke Lowry, Reuben J. Peters, Morrone, Dana, Determan, Mara K., David M. Hershey   +11 more
core   +1 more source

SEED CAROTENOID DEFICIENT Functions in Isoprenoid Biosynthesis via the Plastid MEP Pathway [PDF]

Plant Physiology, 2019
Plastid isoprenoids, a diverse group of compounds that includes carotenoids, chlorophylls, tocopherols, and multiple hormones, are essential for plant growth and development. Here, we identified and characterized SEED CAROTENOID DEFICIENT (SCD), which encodes an enzyme that functions in the biosynthesis of plastid isoprenoids in maize (Zea mays).
Lili Zhang, Xuan Zhang, Xiaoji Wang, Jing Xu, Min Wang, Lin Li, Guanghong Bai, Hui Fang, Shuting Hu, Jigang Li, Jianbing Yan, Jiansheng Li, Xiaohong Yang   +12 more
openaire   +2 more sources

Biosynthesis of β-carotene in engineered E. coli using the MEP and MVA pathways [PDF]

Microbial Cell Factories, 2014
β-carotene is a carotenoid compound that has been widely used not only in the industrial production of pharmaceuticals but also as nutraceuticals, animal feed additives, functional cosmetics, and food colorants. Currently, more than 90% of commercial β-carotene is produced by chemical synthesis.
Yang, Jianming, Guo, Lizhong
openaire   +2 more sources

Final model for prediction of terpinen-4-ol concentrations from transcript levels of MEP pathway genes.

, 2013
Final model for prediction of terpinen-4-ol concentrations from transcript levels of MEP pathway genes.
Robert Lanfear (395145), John Hamill (395148), William J. Foley (395149), Carsten Külheim (395150), Hamish Webb (395143)   +4 more
core   +1 more source

New opportunities for bioscaffold‐enabled spinal cord injury repair

BMEMat, EarlyView.
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi, Yicheng Fu, Zhaoliang Su, Li Li, Subrata Chakrabarti, Peng Li, Yilun Wu, Fang Liu, Teng Gao, Zhifeng Dong, Lei Liu, Pei Cao   +11 more
wiley   +1 more source

Additional file 2: of Transcriptomic profiling reveals MEP pathway contributing to ginsenoside biosynthesis in Panax ginseng

, 2019
Table S2. Primer sequences of the genes of the MEP pathway of P.
Zilong He (5830418), Xiaochun Bi (6711887), Shuangxiu Wu (644349), Songnian Hu (6480), Wei Xu (28953), Ting Wei (113015), Le Xue (5058113)   +6 more
core   +1 more source

Homologous membrane wrapped ZIF‐8 nanoparticles accelerate differentiation of neural stem cell for spinal cord injury therapy

BMEMat, EarlyView.
Homologous membrane wrapped ZIF‐8 nanoparticles were proposed to improve biocompatibility and targeting ability to neural stem cells (NSCs). ZIF‐8‐SCM NPs exhibit pH responsiveness, thereby generating an intracellular Zn2+ storm to accelerate neural differentiation through calcium and MAPK signaling pathways. Moreover, they promote function recovery in
Jie Wang, Lusen Shi, Xinhui Liu, Zhong Zhuang, Zhichao Feng, Chunhui Sun, Jingang Wang, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Shuping Wang, Hengxing Zhou, Na Ren   +11 more
wiley   +1 more source

Tracing the biosynthetic origin of limonoids and their functional groups through stable isotope labeling and inhibition in neem tree (Azadirachta indica) cell suspension

BMC Plant Biology, 2018
Background Neem tree serves as a cornucopia for triterpenoids called limonoids that are of profound interest to humans due to their diverse biological activities.
Thiagarayaselvam Aarthy, Fayaj A. Mulani, Avinash Pandreka, Ashish Kumar, Sharvani S. Nandikol, Saikat Haldar, Hirekodathakallu V. Thulasiram   +6 more
doaj   +1 more source

Transforming Brain Health With Neurotechnology Convergence (Part II): Intelligent Neurointervention Systems for Neurological Disorders

Brain Health, EarlyView.
ABSTRACT Neurological disorders represent a critical domain within global health, necessitating advanced interventions to address complex pathologies such as tumors, functional disorders, and cerebrovascular diseases. Despite the proven benefits of early intervention, current treatment paradigms face significant challenges: (1) limited precision in ...
Qing Ye, Fei Peng, Chao Pan, Ping Zhang, Xuewei Xie, Zixiao Li, Yingxin Tang, Danyang Chen, Yuanwei Li, Jiawen Wu, Zao Han, Qing Dai, Quansheng Gu, Jizong Zhao, Zhouping Tang   +14 more
wiley   +1 more source