Results 81 to 90 of about 3,014,380 (256)

Differential Subplastidial Localization and Turnover of Enzymes Involved in Isoprenoid Biosynthesis in Chloroplasts. [PDF]

PLoS ONE, 2016
Plastidial isoprenoids are a diverse group of metabolites with roles in photosynthesis, growth regulation, and interaction with the environment. The methylerythritol 4-phosphate (MEP) pathway produces the metabolic precursors of all types of plastidial ...
Catalina Perello, Ernesto Llamas, Vincent Burlat, Miriam Ortiz-Alcaide, Michael A Phillips, Pablo Pulido, Manuel Rodriguez-Concepcion   +6 more
doaj   +1 more source

A Single Nucleotide Mutation of the IspE Gene Participating in the MEP Pathway for Isoprenoid Biosynthesis Causes a Green-Revertible Yellow Leaf Phenotype in Rice

Plant and Cell Physiology, 2018
Plant isoprenoids are dependent on two independent pathways, the cytosolic mevalonate (MVA) pathway and the plastidic methylerythritol phosphate (MEP) pathway. IspE is one of seven known enzymes in the MEP pathway.
N. Chen, Pingrong Wang, Chunmei Li, Qian Wang, Jihong Pan, Fuliang Xiao, Yang Wang, Kuan Zhang, Caixia Li, Bin Yang, Changhui Sun, Xiaojian Deng   +11 more
semanticscholar   +1 more source

DCAF13 Safeguards Hematopoietic Stem Cells via RRS1‐Regulated Ribosome Biogenesis

Advanced Science, EarlyView.
This study establishes DCAF13 as an essential regulator for hematopoietic stem cell (HSC) function. Its deletion in mice causes lethal pancytopenia and HSC depletion. Mechanistically, DCAF13 interacts with RRS1 and mediates its non‐degradative K27‐linked ubiquitination, thereby stabilizing RRS1 to maintain ribosome biogenesis and protein translation ...
Mengke Li, Yuxin Wu, Shuai Zhou, Peipei Tang, Jiaming Wei, Ling Liu, Zhenyi Wang, Deyang Shi, Shengnan Yuan, Qingyu Zhang, Shihui Wang, Qing Zhang, Huan Zhao, Rui Zhang, Yingying Wang, Shiwei Yang, Xiangli Chen, Xiaojing Shi, Guangzhi Liu, Yuwei Zhang, Jinming Li, Xu Dong Zhang, Rick F Thorne, Dongping Wei, Zumin Zhu, Song Chen   +25 more
wiley   +1 more source

Coordinated carbon metabolite flux between the methyl erythritol phosphate (MEP) and the mevalonate (MVA) pathway regulates the withanolide biosynthesis in Withania somnifera (L.) Dunal

Discover Plants
Withanolides are bioactive triterpenoids that require isoprene units viz., isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) as precursor molecule for their biosynthesis, mediated via two independent routes, the plastidial methyl ...
Prince Choyal, Virendra Singh Rana, Maharishi Tomar, Kalidindi Usha, Bhupinder Singh   +4 more
doaj   +1 more source

Dynamics of Monoterpene Formation in Spike Lavender Plants

Metabolites, 2017
The metabolic cross-talk between the mevalonate (MVA) and the methylerythritol phosphate (MEP) pathways was analyzed in spike lavender (Lavandula latifolia Med) on the basis of 13CO2-labelling experiments using wildtype and transgenic plants ...
Isabel Mendoza-Poudereux, Erika Kutzner, Claudia Huber, Juan Segura, Isabel Arrillaga, Wolfgang Eisenreich   +5 more
doaj   +1 more source

Biosynthesis of β-carotene in engineered E. coli using the MEP and MVA pathways [PDF]

Microbial Cell Factories, 2014
β-carotene is a carotenoid compound that has been widely used not only in the industrial production of pharmaceuticals but also as nutraceuticals, animal feed additives, functional cosmetics, and food colorants. Currently, more than 90% of commercial β-carotene is produced by chemical synthesis.
Yang, Jianming, Guo, Lizhong
openaire   +2 more sources

Rapid Remodeling of the Human Gut Microbiome in Response to Short‐Term Animal Product Restriction and Associations with Host Molecular Phenotypes

Advanced Science, EarlyView.
A real‐world model of structured animal product restriction practiced for religious reasons reveals the dynamic adaptability of the human gut microbiome to dietary change and uncovers reductions in diversity and rare taxa loss. Integrated microbiome, metabolomic, and proteomic analyses uncover coordinated taxonomic and molecular shifts and identify ...
Christina Emmanouil, Maria Anezaki, Alexandros Simistiras, Stavros Glentis, Nikolaos Scarmeas, Pantelis Hatzis, Konstantinos Rouskas, Antigone S. Dimas   +7 more
wiley   +1 more source

Pulsed Electromagnetic Fields: A Novel Attractive Therapeutic Opportunity for Neuroprotection After Acute Cerebral Ischemia

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Acute cerebral ischemia is characterized by several pathological processes evolving during time, which contribute to the final tissue damage. Secondary processes, such as prolonged inflammatory response, impaired mitochondrial function and oxidative stress, are responsible for the progression of brain injury to the peri‐infarct area,
Fioravante Capone, Simona Salati, Fabrizio Vincenzi, Micaela Liberti, Giorgio Aicardi, Francesca Apollonio, Katia Varani, Ruggero Cadossi, Vincenzo Di Lazzaro   +8 more
wiley   +1 more source

The methylerythritol phosphate pathway as an oxidative stress sense and response system

Nature Communications
The methylerythritol phosphate (MEP) pathway is responsible for biosynthesis of the precursors of isoprenoid compounds in eubacteria and plastids. It is a metabolic alternative to the well-known mevalonate pathway for isoprenoid production found in ...
Jordi Perez-Gil, James Behrendorff, Andrew Douw, Claudia E. Vickers   +3 more
doaj   +1 more source

Overexpression of 1-deoxy-D-xylulose-5-phosphate reductoisomerase enhances the monoterpene content in Litsea cubeba

Forestry Research, 2023
Monoterpenes are important components of plant essential oils and have long been used as raw materials for spices and food flavorings. Litsea cubeba is an economically aromatic plant species, the fruits of which produce essential oil with monoterpenes as
Yunxiao Zhao, Yingguan Liu, Yicun Chen, Ming Gao, Liwen Wu, Yangdong Wang   +5 more
doaj   +1 more source