Technical performance and diagnostic utility of the new Elecsys (R) neuron-specific enolase enzyme immunoassay [PDF]
, 2003 This international multicenter study was designed to evaluate the technical performance of the new double-monoclonal, single-step Elecsys neuron-specific enolase (NSE) enzyme immunoassay (EIA) and to assess its utility as a sensitive and specific test ...
Chang SF +18 more
core +1 more source
Secondary Merkel Cell Carcinoma Manifested in the Parotid
Case Reports in Dermatological Medicine, 2013 Background. Merkel cell carcinoma of the head and neck is a rare and aggressive malignant tumour. Both the dermatological and surgical colleagues should be aware of this entity as lesions usually present on sun exposed areas of the skin such as the head ...
M. Basati, K. Kassam, A. Messiha
doaj +1 more source
The dual specificity phosphatase 2 gene is hypermethylated in human cancer and regulated by epigenetic mechanisms [PDF]
, 2016 Background: Dual specificity phosphatases are a class of tumor-associated proteins involved in the negative regulation of the MAP kinase pathway. Downregulation of the dual specificity phosphatase 2 (DUSP2) has been reported in cancer.
Dammann, Reinhard H. +4 more
core +2 more sources
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary Background and Objectives Deep learning‐convolutional neural networks (DL‐CNNs) have demonstrated high diagnostic accuracy within the domain of dermoscopy. However, many clinical settings lack dermoscopic devices, requiring reliance on close‐up images. This study evaluates the robustness of a DL‐CNN trained on dermoscopic images when challenged
Anastasia Sophie Vollmer +6 more
wiley +1 more source
Merkel cell carcinoma of the abdominal wall
Indian Dermatology Online Journal, 2015 Merkel cell carcinoma also known as neuroendocrine carcinoma of the skin is a very rare skin tumor. It commonly presents in the old age and the common sites are head, neck and extremities.
Vandana L Gaopande +3 more
doaj +1 more source
No Evidence of Human Polyomavirus 9, WU and KI DNA in Kidney and Urinary Bladder Tumour Tissue Samples [PDF]
, 2016 KAL
Bidiga, László +3 more
core +1 more source
Neoadjuvant therapy in skin cancer: current evidence and future perspectives
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary The development of immune checkpoint inhibitors and targeted therapies has fundamentally changed the treatment of cutaneous malignancies, especially in squamous cell carcinoma, melanoma, and Merkel cell carcinoma. The latest neoadjuvant approaches have shown promising results in locally advanced stages.
Lea Daniello +2 more
wiley +1 more source
Merkel Cell Carcinoma: Case Report and Literature Review
Revista Iberoamericana de Cirugía de la Mano, 2020 Merkel Cell Carcinoma is a rare type of aggressive and often fatal neuroendocrine tumor of the skin. We report a clinical case of a 56-year-old female with a Merkel cell carcinoma on the left hand, without distant metastasis, treated with surgical ...
Margarida Areias Marques Miranda +4 more
doaj +1 more source
The cellular chloride channels CLIC1 and CLIC4 contribute to virus-mediated cell motility [PDF]
, 2018 Ion channels regulate many aspects of cell physiology, including cell proliferation, motility, and migration, and aberrant expression and activity of ion channels is associated with various stages of tumor development, with K⁺ and Cl⁻ channels now being ...
Adrian Whitehouse +49 more
core +2 more sources
APOBEC-related mutagenesis and neo-peptide hydrophobicity: implications for response to immunotherapy. [PDF]
, 2019 Tumor-associated neo-antigens are mutated peptides that allow the immune system to recognize the affected cell as foreign. Cells carrying excessive mutation load often develop mechanisms of tolerance.
Boichard, Amélie +8 more
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