Results 171 to 180 of about 7,231 (207)

Spatially organized inflammatory myeloid-CD8 + T cell aggregates linked to Merkel-cell Polyomavirus driven Reorganization of the Tumor Microenvironment

open access: yes
Haist M   +19 more
europepmc   +1 more source

Merkel cell polyomavirus-specific and CD39<sup>+</sup>CLA<sup>+</sup> CD8 T cells as blood-based predictive biomarkers for PD-1 blockade in Merkel cell carcinoma. [PDF]

open access: yesCell Rep Med
Ryu H   +14 more
europepmc   +1 more source

Merkel cell polyomavirus and Merkel cell carcinoma [PDF]

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2017
Merkel cell polyomavirus (MCPyV) causes the highly aggressive and relatively rare skin cancer known as Merkel cell carcinoma (MCC). MCPyV also causes a lifelong yet relatively innocuous infection and is one of 14 distinct human polyomaviruses species.
James A DeCaprio
exaly   +3 more sources

Prevalence of Merkel cell polyomavirus in Merkel cell carcinoma [PDF]

open access: yesModern Pathology, 2009
It has recently been shown that Merkel cell carcinoma, a rare and often lethal cutaneous malignancy, frequently harbors a novel clonally integrated polyomavirus aptly named Merkel cell polyomavirus. We aimed to study the prevalence of Merkel cell polyomavirus in cases of Merkel cell carcinoma, using specimens from formalin-fixed, paraffin-embedded ...
Eric J Duncavage   +2 more
exaly   +3 more sources

Merkel Cell Polyomavirus and Human Merkel Cell Carcinoma

2020
Merkel cell polyomavirus (MCPyV) is the most recently discovered human oncogenic virus. MCPyV asymptomatically infects most of the human population. In the elderly and immunocompromised, however, it can cause a highly lethal form of human skin cancer called Merkel cell carcinoma (MCC).
Wei, Liu, Jianxin, You
openaire   +2 more sources

Detection of Merkel cell polyomavirus DNA in Merkel cell carcinomas

British Journal of Dermatology, 2009
Merkel cell carcinoma (MCC) is a rare, aggressive tumour for which an increasing incidence has been reported. A new human polyomavirus, Merkel cell polyomavirus (MCV), was recently isolated from these tumours by applying digital transcriptome subtraction methodology.To detect the presence or absence of MCV in MCCs and other, randomly selected neoplasms.
M Kiss, Lajos Kemeny
exaly   +3 more sources

Detection of Merkel cell polyomavirus in Merkel cell carcinoma and Kaposi's sarcoma

Journal of Medical Virology, 2009
AbstractMerkel cell carcinoma is a rare malignancy that sometimes occurs in the skin of elderly people. Recently, a new human polyomavirus, Merkel cell polyomavirus (MCPyV) was identified in Merkel cell carcinoma. In the present study, MCPyV‐DNA was detected in 6 of 11 (55%) cases of Merkel cell carcinoma by nested PCR and real‐time PCR. Histologically,
Harutaka Katano   +2 more
exaly   +3 more sources

The Merkel Cell Polyomavirus and Its Involvement in Merkel Cell Carcinoma

Dermatologic Surgery, 2013
The discovery of the Merkel cell polyomavirus (MCV) in a large number of Merkel cell carcinomas (MCCs) has led to many investigations into its potential role as an oncovirus. Many studies have recently explored the differences between MCCs infected and not infected with MCV.To review the role of MCV in MCC and its potential to influence diagnosis ...
Kyle, Amber   +2 more
openaire   +2 more sources

Merkel Cell Polyomavirus

2014
Merkel cell polyomavirus (MCV) is a recently discovered member of the polyomaviridae, a family of small DNA viruses that replicate in the nucleus of their host cell. MCV is one of at least 12 polyomaviruses that naturally infect humans, and furthermore one of four polyomaviruses that are known to cause severe human disease, predominantly in ...
Nicole Fischer, Adam Grundhoff
openaire   +1 more source

Home - About - Disclaimer - Privacy