Results 181 to 190 of about 7,231 (207)

Merkel Cell Polyomavirus

2011
Merkel cell carcinoma (MCC) is the most aggressive tumor of the skin. Nevertheless, until recently, almost only dermatologists were aware of MCC which was due to the rareness of this neuroendocrine carcinoma. This, however, changed in 2008 when a new polyomavirus, which was named Merkel cell polyomavirus (MCV or MCPyV), was found associated with MCC ...
David Schrama, Jürgen C. Becker
openaire   +1 more source

Genetic variability and integration of Merkel cell polyomavirus in Merkel cell carcinoma

Virology, 2012
Merkel cell polyomavirus (MCPyV) is associated to Merkel cell carcinoma (MCC). We studied 113 MCC tumoral skin lesions originating from 97 patients. MCPyV detection was higher in fresh-frozen (FF) biopsies (94%) than in formalin-fixed paraffin-embedded biopsies (39-47%).
G Tomasic, P Vielh, G Jouvion
exaly   +3 more sources

Merkel Cell Polyomavirus

American Journal of Surgical Pathology, 2009
The recently described Merkel cell polyomavirus (MCPyV) is reportedly present in 50% to 80% of Merkel cell carcinomas (MCC). Although the virus has been shown to be absent from other cutaneous neoplasms, its association with malignancies that are histologically similar to MCC, specifically small cell carcinoma of the lung and other high-grade ...
Eric J, Duncavage, Binh-Minh, Le, David, Wang, John D, Pfeifer   +3 more
openaire   +2 more sources

Usefulness of significant morphologic characteristics in distinguishing between Merkel cell polyomavirus–positive and Merkel cell polyomavirus–negative Merkel cell carcinomas

Human Pathology, 2013
Merkel cell polyomavirus (MCPyV) monoclonally integrates into genomes of approximately 80% of Merkel cell carcinomas (MCCs) and undergoes mutation. We previously demonstrated statistically significant differences in tumor cell morphology and biology between MCPyV-positive and MCPyV-negative MCCs. We reassessed the usefulness of our morphologic criteria
Takeshi Iwasaki, Michiko Matsushita, Satoshi Kuwamoto   +2 more
exaly   +3 more sources

The prevalence of Merkel cell polyomavirus in Japanese patients with Merkel cell carcinoma

Journal of Dermatological Science, 2013
A novel polyomavirus, the Merkel cell polyomavirus (MCPyV) has been implicated in the pathogenesis of Merkel cell carcinoma (MCC); however, the prevalence of MCPyV in Japan has not been extensively investigated.To clarify the prevalence of MCPyV in Japanese patients with MCC.MCPyV DNA was examined by polymerase chain reaction (PCR) in formalin-fixed ...
Tomoyasu, Hattori, Yuko, Takeuchi, Tatsuya, Takenouchi, Akiko, Hirofuji, Tetsuya, Tsuchida, Takenori, Kabumoto, Hiroshi, Fujiwara, Masaaki, Ito, Akira, Shimizu, Etsuko, Okada, Sei-ichiro, Motegi, Atsushi, Tamura, Osamu, Ishikawa   +12 more
openaire   +2 more sources

Merkel Cell Polyomavirus (MCPyV)

2020
No abstract available.
Sofia, Asioli, Ricci, Costantino
openaire   +2 more sources

Merkel Cell Polyomavirus in Merkel Cell Carcinoma: Clinical and Therapeutic Perspectives

Seminars in Oncology, 2015
Merkel cell carcinoma (MCC) is a rare and often aggressive cutaneous cancer with a poor prognosis. The incidence of this cancer increases with age, immunodeficiency and sun exposure. Merkel cell polyomavirus (MCPyV), a new human polyomavirus identified in 2008, is detected in the majority of the MCCs and there is a growing body of evidence that healthy
Samimi-Gharaei, Mahtab, Gardair, Charlotte, Nicol, Jérôme, Arnold, Françoise, Touzé, Antoine, Coursaget, Pierre   +5 more
openaire   +3 more sources

Merkel cell polyomavirus: an update

Journal of Cutaneous Pathology, 2009
Rishi K, Gandhi, Arlene S, Rosenberg, Stephen C, Somach   +2 more
openaire   +2 more sources

Merkel cell polyomavirus

2013
International ...
openaire   +1 more source

Merkel Cell Polyomavirus: Oncogenesis in a Stable Genome

Viruses, 2022
Mona M Ahmed, Camille H Cushman, James A DeCaprio   +2 more
exaly