Results 1 to 10 of about 139,532 (214)

Mesenchymal stem cell and hematopoietic stem cell transplantation for vasculitis

open access: yesVascular Investigation and Therapy, 2020
Vasculitis is a great therapeutic challenge. Currently, no effective treatments are available. Although biologics are emerging as new therapeutic alternatives, steroids remain the mainstay of the treatment.
Lianming Liao
doaj   +2 more sources

Mesenchymal Stem Cell Transplantation Increases Antioxidant Protein Expression and Ameliorates GP91/ROS/Inflammasome Signals in Diabetic Cardiomyopathy

open access: yesJournal of Cardiovascular Development and Disease, 2022
Background: Cardiomyopathy is one of the complications associated with diabetes. Due to its high prevalence, diabetic cardiomyopathy has become an urgent issue for diabetic patients.
Wei-Syun Hu   +4 more
doaj   +1 more source

Effects of bone marrow mesenchymal stem cell transplantation on tumor necrosis factor-alpha receptor 1 expression, granulosa cell apoptosis, and folliculogenesis repair in endometriosis mouse models [PDF]

open access: yesVeterinary World, 2021
Background and Aim: Endometriosis affects the ovaries and causes a decrease in the oocyte quality during endometrial receptivity. During the development of ovarian follicles, paracrine communication occurs between granulosa cells and oocytes.
Sri Ratna Dwiningsih   +7 more
doaj   +1 more source

Mesenchymal stem cells in hematopoietic stem cell transplantation [PDF]

open access: yesCytotherapy, 2009
Mesenchymal stromal/stem cells (MSC) of bone marrow (BM) origin not only provide the supportive microenvironmental niche for hematopoietic stem cells (HSC) but are capable of differentiating into various cell types of mesenchymal origin, such as bone, fat and cartilage.
Minoo, Battiwalla, Peiman, Hematti
openaire   +2 more sources

Mitochondrial Transfer Induced by Adipose-Derived Mesenchymal Stem Cell Transplantation Improves Cardiac Function in Rat Models of Ischemic Cardiomyopathy

open access: yesCell Transplantation, 2023
Although mesenchymal stem cell transplantation has been successful in the treatment of ischemic cardiomyopathy, the underlying mechanisms remain unclear.
Daisuke Mori   +14 more
doaj   +1 more source

Mesenchymal stem cells and transplant tolerance [PDF]

open access: yesNephrology, 2014
AbstractDifferent strategies are being tried to induce transplant tolerance in clinical settings; however, none of them are both safe and effective. Mesenchymal stem cells have been found to be potent immunomodulators and immunosuppressants. We discuss in this review different sources of mesenchymal stem cells and the potent role of adipose tissue ...
Aruna V, Vanikar   +4 more
openaire   +2 more sources

Bone marrow mesenchymal stem cells and exercise restore motor function following spinal cord injury by activating PI3K/AKT/mTOR pathway

open access: yesNeural Regeneration Research, 2023
Although many therapeutic interventions have shown promise in treating spinal cord injury, focusing on a single aspect of repair cannot achieve successful and functional regeneration in patients following spinal cord injury .
Xin Sun   +10 more
doaj   +1 more source

Mesenchymal Stem/Stromal Cells in Organ Transplantation

open access: yesPharmaceutics, 2022
Organ transplantation is essential and crucial for saving and enhancing the lives of individuals suffering from end-stage organ failure. Major challenges in the medical field include the shortage of organ donors, high rates of organ rejection, and long wait times.
Dayanand Deo   +2 more
openaire   +3 more sources

Mesenchymal Stem Cell in Pancreatic Islet Transplantation

open access: yesBiomedicines, 2023
Pancreatic islet transplantation is a therapeutic option for achieving physiologic regulation of plasma glucose in Type 1 diabetic patients. At the same time, mesenchymal stem cells (MSCs) have demonstrated their potential in controlling graft rejection, the most fearsome complication in organ/tissue transplantation.
Serena Barachini   +6 more
openaire   +4 more sources

Intracellular role of IL-6 in mesenchymal stromal cell immunosuppression and proliferation

open access: yesScientific Reports, 2020
Interleukin (IL)-6 is a pleiotropic cytokine involved in the regulation of hematological and immune responses. IL-6 is secreted chiefly by stromal cells, but little is known about its precise role in the homeostasis of human mesenchymal stromal cells ...
Akaitz Dorronsoro   +7 more
doaj   +1 more source

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