Mesenchymal Stem Cell Transplantation Increases Antioxidant Protein Expression and Ameliorates GP91/ROS/Inflammasome Signals in Diabetic Cardiomyopathy [PDF]
Journal of Cardiovascular Development and Disease, 2022 Background: Cardiomyopathy is one of the complications associated with diabetes. Due to its high prevalence, diabetic cardiomyopathy has become an urgent issue for diabetic patients.
Wei-Syun Hu +4 more
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Mitochondrial Transfer Induced by Adipose-Derived Mesenchymal Stem Cell Transplantation Improves Cardiac Function in Rat Models of Ischemic Cardiomyopathy [PDF]
Cell Transplantation, 2023 Although mesenchymal stem cell transplantation has been successful in the treatment of ischemic cardiomyopathy, the underlying mechanisms remain unclear.
Daisuke Mori +14 more
doaj +2 more sources
Effects of bone marrow mesenchymal stem cell transplantation on tumor necrosis factor-alpha receptor 1 expression, granulosa cell apoptosis, and folliculogenesis repair in endometriosis mouse models [PDF]
Veterinary World, 2021 Background and Aim: Endometriosis affects the ovaries and causes a decrease in the oocyte quality during endometrial receptivity. During the development of ovarian follicles, paracrine communication occurs between granulosa cells and oocytes.
Sri Ratna Dwiningsih +7 more
doaj +1 more source
Neural Regeneration Research, 2023 Although many therapeutic interventions have shown promise in treating spinal cord injury, focusing on a single aspect of repair cannot achieve successful and functional regeneration in patients following spinal cord injury .
Xin Sun +10 more
doaj +1 more source
Cell therapy of congenital corneal diseases with umbilical mesenchymal stem cells: lumican null mice. [PDF]
PLoS ONE, 2010 Keratoplasty is the most effective treatment for corneal blindness, but suboptimal medical conditions and lack of qualified medical personnel and donated cornea often prevent the performance of corneal transplantation in developing countries.
Hongshan Liu +7 more
doaj +1 more source
Intracellular role of IL-6 in mesenchymal stromal cell immunosuppression and proliferation
Scientific Reports, 2020 Interleukin (IL)-6 is a pleiotropic cytokine involved in the regulation of hematological and immune responses. IL-6 is secreted chiefly by stromal cells, but little is known about its precise role in the homeostasis of human mesenchymal stromal cells ...
Akaitz Dorronsoro +7 more
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Neural Regeneration Research, 2023 Animal experiments have shown that injectable collagen scaffold with human umbilical cord-derived mesenchymal stem cells can promote recovery from spinal cord injury.
Xiao-Yin Li +8 more
doaj +1 more source
Mesenchymal Stem Cells for Busulfan–Induced Azoospermia: An Experimental Study [PDF]
International Journal of Medical Arts, 2022 Background: Busulfan is a frequently used chemotherapeutic agent. It exerts harmful effects on male reproduction. Azoospermia is a major cause of male infertility, and stem cell therapy may be a reasonable treatment option.The aim of the work: The ...
Fawzy Mahmoud Ali Abougalala +4 more
doaj +1 more source
Frontiers in Endocrinology, 2019 Introduction: Cell therapy can overcome the limitation of conventional treatments (including different medications and β cell replacement) for type 1 diabetes.
Babak Arjmand +8 more
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Neural Regeneration Research, 2016 Animal and clinical studies have confirmed the therapeutic effect of bone marrow mesenchymal stem cells on cerebral ischemia, but their mechanisms of action remain poorly understood.
Guihong Li +7 more
doaj +1 more source