Preventing Differentiation Towards Primitive Macrophages in Stem Cells With Down Syndrome
Decreased fetal brain macrophages were previously reported in Ts1Cje mice, a model of Down syndrome (DS). We confirmed the reduction in primitive macrophages, brain macrophage precursors, using Ts1Cje‐derived mouse embryonic stem cells (Ts1Cje‐mESCs) and human induced pluripotent stem cells with trisomy 21 (Tri21‐hiPSCs), with in vivo validation ...
Koki Harada +9 more
wiley +1 more source
Lateral thinking in syndromic congenital cardiovascular disease
Agnese Kocere +3 more
doaj +1 more source
Editor's evaluation: Glycolytic flux-signaling controls mouse embryo mesoderm development
Joshua M. Brickman
openalex +1 more source
A suture in time: The ontogeny of cranial suture morphology in mammals
Mammal cranial sutures are important indicators of the biomechanical and developmental pressures acting upon the skull. Across three prominent sutures dividing the vault of the mammalian skull, divergent patterns emerge both taxonomically and developmentally.
Heather E. White +4 more
wiley +1 more source
Can gastric endoderm change the regionally specific inducing ability of presumptive small intestinal mesoderm? [PDF]
B.B. Rawdon
openalex +1 more source
Mapping the murine TMJ glenoid fossa over development, homeostasis and in response to disease
The fibrocartilage of the murine glenoid fossa and condyle of the temporomandibular joint are shown to form at distinct times with distinct molecular identities. Changes in the condyle during disease lead to remodelling of the fossa to maintain joint alignment.
Ticha Tuwatnawanit +4 more
wiley +1 more source
Why and How Are Infants with Hutchinson-Gilford Progeria Syndrome Born Without Severe Manifestations? [PDF]
Erokhina MA +3 more
europepmc +1 more source
Animals were sensitized with mBSA emulsified in CFA/IFA and subsequently received three intra‐articular injections of mBSA into either the TMJ or the knee (once per week). Mechanical hyperalgesia was assessed using electronic von Frey testing after arthritis establishment at 24 h or 7 days following the third intra‐articular injection.
Ana Carolina de Figueiredo Costa +2 more
wiley +1 more source
Distinct roles of Atf3, Zfp711 and Bcl6b in early embryonic hematopoietic and endothelial lineage specification. [PDF]
Cetin R +13 more
europepmc +1 more source

