Results 181 to 190 of about 94,714 (283)

Paxillin is crucial for thymus and parathyroid development by regulating the architecture of the third pharyngeal pouch endoderm. [PDF]

open access: yesCell Mol Life Sci
Iacolare O   +6 more
europepmc   +1 more source

Escaping Constraints to Innovate: Maternal Neofunctionalization in a HoxB4 Duplicate

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 346, Issue 2, Page 141-151, March 2026.
Whole‐genome duplication in Xenopus laevis generated duplicated Hox genes that are largely constrained in sequence and developmental expression. However, HoxB4L uniquely acquired maternal expression through cis‐regulatory and protein structural divergence, illustrating how gene duplication enables transcription factors to escape pleiotropic constraints
Júlia de Lima Carvalho   +2 more
wiley   +1 more source

VGLL1 contributes to both the transcriptome and epigenome of the developing trophoblast compartment. [PDF]

open access: yesProc Natl Acad Sci U S A
Calderon RI   +21 more
europepmc   +1 more source

A Clearer Picture: Using Fetal MRI to Diagnose Neck Masses and Predict Airway Compromise

open access: yesPrenatal Diagnosis, Volume 46, Issue 3, Page 339-347, March 2026.
ABSTRACT Introduction Fetal neck masses are rare but can be life‐threatening if causing airway compromise. Early and accurate diagnosis of these masses allows life‐saving interventions to be undertaken at birth in the form of the EXIT procedure. Methods A single institution case series of all patients referred for fetal MRI to a tertiary center in the ...
Louise Wilson   +2 more
wiley   +1 more source

Meflin/ISLR is a meningeal cell‐specific marker involved in the development of meninges and meningioma progression

open access: yesBrain Pathology, Volume 36, Issue 2, March 2026.
Mesenchymal stromal cell‐and fibroblast‐expressing Linx paralogue (Meflin) is expressed in embryonic meninges and contributes to meningeal homeostasis. In meningiomas, elevated Meflin correlates with higher grade and recurrence. Single‐cell RNA sequencing revealed a Meflin‐high tumor cell subset marked by reduced proliferation, WNT6 expression, and ...
Yukihiro Shiraki   +13 more
wiley   +1 more source

Construction and Expression Analysis of the <i>bin <sup>3xOllas</sup></i> Tool Line. [PDF]

open access: yesMicroPubl Biol
Yi M   +3 more
europepmc   +1 more source

Vascularised Brain Organoids: Engineering Strategies and Neurobiological Applications

open access: yesCell Proliferation, Volume 59, Issue 3, March 2026.
This review highlights emerging strategies to engineer vascularized brain organoids—including endothelial co‐culture, genetic induction, perfusion systems, and in vivo transplantation—and their applications in modelling neurovascular diseases, evaluating BBB drug delivery, and advancing regenerative medicine.
Yeajin Song   +4 more
wiley   +1 more source

BMP4 initiates and patterns ventral-caudal structures in zebrafish and human pluripotent stem cell aggregates. [PDF]

open access: yesEMBO J
Xing YY   +14 more
europepmc   +1 more source

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