Results 231 to 240 of about 99,345 (353)

BMP/SMAD1 signaling sets a threshold for the left/right pathway in lateral plate mesoderm and limits availability of SMAD4 [PDF]

, 2008
Milena B. Furtado, Mark J. Solloway, Vanessa Jones, Mauro W. Costa, Christine Biben, Orit Wolstein, Jost I. Preis, Duncan B. Sparrow, Yumiko Saga, Sally L. Dunwoodie, Elizabeth J. Robertson, Patrick Tam, Richard P. Harvey   +12 more
openalex   +1 more source

Mosaic Li Fraumeni Syndrome Not Identified in Germinal Tissue

Molecular Genetics &Genomic Medicine, Volume 14, Issue 2, February 2026.
In this study, we presented the first clinical case report of mosaic Li Fraumeni syndrome eluding germinal tissue. This case highlights the complexity of interpreting mosaic variants in TP53, and the difficulty in relaying cancer and reproductive risk information in the context of mosaic Li Fraumeni syndrome.
Rhianna M. Urban, Nisha Kanwar, Megan A. Holdren, Megan F. Hoenig, Laura M. Rust, Myra J. Wick, Matthew J. Ferber, Zhiyv Niu, Sounak Gupta, Wei Shen   +9 more
wiley   +1 more source

Speed of life: tuning the ticktock of the segmentation clock. [PDF]

Genes Dev
Lowell S.
europepmc   +1 more source

Single‐nucleus RNA sequencing identifies a novel tenogenic heterologous differentiation in endometrial carcinosarcomas: implications for diagnosis and tumor classification

The Journal of Pathology, Volume 268, Issue 2, Page 227-242, February 2026.
Abstract Carcinosarcomas (CSs) are aggressive biphasic tumors characterized by epithelial and mesenchymal components, whose histogenesis and differentiation dynamics remain poorly understood. We present single‐nucleus RNA sequencing (snRNA‐seq) analysis of six CSs (five endometrial and one ovarian) and two normal endometrial samples, profiling over 96 ...
Silvia González‐Martínez, José Palacios, Irene Carretero‐Barrio, Val Fernández‐Lanza, Alfonso Cortés‐Salgado, Javier Román, Xavier Matias‐Guiu, Sonia Gatius, Javier Cortés, Belén Pérez‐Mies   +9 more
wiley   +1 more source

Sox8 is essential for vertebrate gastrulation. [PDF]

EMBO Rep
Moreira S, Korovesi AG, Barriga EH.
europepmc   +1 more source

β-Catenin regulates Cripto- and Wnt3-dependent gene expression programs in mouse axis and mesoderm formation

, 2003
Markus Morkel, Joerg Huelsken, Maki Wakamiya, Jixiang Ding, Marc van de Wetering, Hans Clevers, Makoto M. Taketo, Richard R. Behringer, Michael M. Shen, Walter Birchmeier   +9 more
openalex   +2 more sources

MSC‐Derived Exosomal lnc‐AGT‐3: A Novel Anti‐Angiogenic Target in Age‐Related Macular Degeneration Through p53 Signaling Pathway

Aging Cell, Volume 25, Issue 2, February 2026.
MSC‐derived exosomes deliver lnc‐AGT‐3 to vascular endothelial cells, where it binds hnRNP K in the nucleus. This interaction inhibits p53 ubiquitination, enhancing p53 stabilization and transcriptional activation of anti‐angiogenic targets TSP1. Consequently, p53‐mediated signaling is potentiated, effectively suppressing choroidal neovascularization ...
Lingjie Kong, Xiaoyan Han, Siyi Qi, Duo Li, Jingyue Zhang, Linyu Zhang, Shujie Zhang, Qin Jiang, Biao Yan, Chen Zhao   +9 more
wiley   +1 more source

Keeping up with the neighbours: local synchronisation of cell fate decisions during development. [PDF]

EMBO Rep
Lowell S.
europepmc   +1 more source

Pig embryonic stem cells with porcine specific-MSGN1 upstream region-based reporter system for monitoring paraxial mesoderm differentiation

Jinsol Jeong, Kwang‐Hwan Choi, Dong‐Kyung Lee, Yelim Ahn, Chang-Kyu Lee   +4 more
openalex   +1 more source

MSC‐Derived Secretome and Exosomes in Dermatology: Mechanisms, Therapeutic Opportunities, and Scientific Challenges—A Narrative Review

International Journal of Dermatology, Volume 65, Issue 2, Page 257-272, February 2026.
ABSTRACT Mesenchymal stromal cells (MSCs) exert their effects primarily through paracrine signaling via soluble factors and extracellular vesicles (EVs), especially exosomes. These acellular components offer regenerative and immunomodulatory benefits with fewer safety and logistical constraints than cell‐based therapies.
Marcela da Costa Pereira Cestari, Reinaldo Falavigna Tovo, Daniela Franco Bueno   +2 more
wiley   +1 more source