Results 1 to 10 of about 116,098 (154)
Metabolic Flexibility of Sulfate Reducing Bacteria [PDF]
Frontiers in Microbiology, 2011 Dissimilatory sulfate-reducing prokaryotes (SRB) are a very diverse group of anaerobic bacteria that are omnipresent in nature and play an imperative role in the global cycling of carbon and sulfur.
Caroline M. Plugge +3 more
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Perspectives on whole body and tissue-specific metabolic flexibility and implications in cardiometabolic diseases [PDF]
Cell Reports MedicineSummary: Metabolic flexibility is the body’s ability to switch between fuel sources in response to changing supply. This adaptability is crucial for maintaining energy balance and metabolic homeostasis, involving key processes like insulin signaling ...
Jia-Hui Christy Ang +6 more
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Metabolic flexibility during sleep [PDF]
Scientific Reports, 2021 Known as metabolic flexibility, oxidized substrate is selected in response to changes in the nutritional state. Sleep imposes an extended duration of fasting, and oxidized substrates during sleep were assumed to progressively shift from carbohydrate to ...
Simeng Zhang +12 more
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Editorial: Metabolic Flexibility
Frontiers in Nutrition, 2022 International ...
Jose E. Galgani +7 more
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Metabolic Flexibility in Health and Disease [PDF]
Cell Metabolism, 2017 Metabolic flexibility is the ability to respond or adapt to conditional changes in metabolic demand. This broad concept has been propagated to explain insulin resistance and mechanisms governing fuel selection between glucose and fatty acids, highlighting the metabolic inflexibility of obesity and type 2 diabetes.
Lauren Sparks, Bret Goodpaster
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Impaired Metabolic Flexibility in the Osteoarthritis Process: A Study on Transmitochondrial Cybrids
Cells, 2020 Osteoarthritis (OA) is the most frequent joint disease; however, the etiopathogenesis is still unclear. Chondrocytes rely primarily on glycolysis to meet cellular energy demand, but studies implicate impaired mitochondrial function in OA pathogenesis ...
Andrea Dalmao-Fernández +6 more
doaj +3 more sources
Metabolic flexibility and obesity in children and youth [PDF]
Obesity Reviews, 2011 SummaryThe concept of metabolic flexibility describes the ability of skeletal muscle to switch between the oxidation of lipid as a fuel during fasting periods to the oxidation of carbohydrate during insulin stimulated period. Alterations in energy metabolism in adults with obesity, insulin resistance and/or type 2 diabetes induce a state of impaired ...
Brian W Timmons
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Altered Metabolic Flexibility in Inherited Metabolic Diseases of Mitochondrial Fatty Acid Metabolism [PDF]
International Journal of Molecular Sciences, 2021 In general, metabolic flexibility refers to an organism’s capacity to adapt to metabolic changes due to differing energy demands. The aim of this work is to summarize and discuss recent findings regarding variables that modulate energy regulation in two different pathways of mitochondrial fatty metabolism: β-oxidation and fatty acid biosynthesis.
Sara Tucci, Khaled Alatibi, Zoe Wehbe
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Exercise-Induced Muscle–Fat Crosstalk: Molecular Mediators and Their Pharmacological Modulation for the Maintenance of Metabolic Flexibility in Aging [PDF]
PharmaceuticalsRegular physical activity induces a dynamic crosstalk between skeletal muscle and adipose tissue, modulating the key molecular pathways that underlie metabolic flexibility, mitochondrial function, and inflammation.
Amelia Tero-Vescan +5 more
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Relation of adipose tissue to metabolic flexibility [PDF]
Diabetes Research and Clinical Practice, 2009 Metabolic flexibility is the capacity for skeletal muscle to shift reliance between lipids and glucose during fasting or in response to insulin. We hypothesized that body fat, adipose tissue characteristics, e.g. larger adipocytes, presence of inflammatory gene markers and impaired suppression of non-esterified fatty acids (NEFAs) during insulin ...
George Bray +2 more
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