Results 41 to 50 of about 116,098 (154)

Impact des traits d’histoire de vie du microcèbe (Microcebus murinus) dans la régulation du métabolisme en réponse à l’environnement

Revue de Primatologie
The grey mouse lemur is a primate endemic from Madagascar, which environmental conditions can vary from season to season, both predictably and unpredictably. To survive such difficult conditions, this small primate (weighing less than 100g) has developed
Jérémy Terrien
doaj   +1 more source

Foetal life protein restriction in male mink (Neovison vison) kits lowers post-weaning protein oxidation and the relative abundance of hepatic fructose-1,6-bisphosphatase mRNA

Animal, 2012
Foetal life malnutrition has been studied intensively in a number of animal models. Results show that especially foetal life protein malnutrition can lead to metabolic changes later in life.
C.F. Matthiesen, D. Blache, P.D. Thomsen, A.-H. Tauson   +3 more
doaj   +1 more source

Loss of Metabolic Flexibility in the Failing Heart

Frontiers in Cardiovascular Medicine, 2018
To maintain its high energy demand the heart is equipped with a highly complex and efficient enzymatic machinery that orchestrates ATP production using multiple energy substrates, namely fatty acids, carbohydrates (glucose and lactate), ketones and amino acids.
Qutuba G. Karwi, Golam M. Uddin, Kim L. Ho, Gary D. Lopaschuk   +3 more
openaire   +3 more sources

Comparative Morphophysiological Analyses and Molecular Profiling Reveal Pi-Efficient Strategies of a Traditional Rice Genotype

Frontiers in Plant Science, 2016
Phosphate (Pi) deficiency severely affects crop yield. Modern high yielding rice genotypes are sensitive to Pi deficiency whereas traditional rice genotypes are naturally compatible with low Pi ecosystems. However, the underlying molecular mechanisms for
Poonam eMehra, Bipin Kumar Pandey, Jitender eGiri   +2 more
doaj   +1 more source

Metabolic flexibility is conserved in diabetic myotubes [PDF]

Journal of Lipid Research, 2007
The purpose of this study was to test the hypothesis that metabolic inflexibility is an intrinsic defect. Glucose and lipid oxidation were studied in human myotubes established from healthy lean and obese subjects and patients with type 2 diabetes (T2D).
openaire   +4 more sources

Metabolic switching of human myotubes is improved by n-3 fatty acids

Journal of Lipid Research, 2010
The aim of the present study was to examine whether pretreatment with different fatty acids, as well as the liver X receptor (LXR) agonist T0901317, could modify metabolic switching of human myotubes.
N.P. Hessvik, S.S. Bakke, K. Fredriksson, M.V. Boekschoten, A. Fj⊘rkenstad, G. Koster, M.K. Hesselink, S. Kersten, E.T. Kase, A.C. Rustan, G.H. Thoresen   +10 more
doaj   +1 more source

Diagnostics of ^ν_La.max and Glycolytic Energy Contribution Indicate Individual Characteristics of Anaerobic Glycolytic Energy Metabolism Contributing to Rowing Performance

Metabolites, 2023
The diagnostics of anaerobic glycolytic metabolism which play a subordinate role in elite rowing and parameters such as maximum lactate accumulation rate (νLa.max) have thus far not been associated with ergometer rowing performance.
Frederik Schünemann, So-Young Park, Corinna Wawer, Christian Theis, Woo-Hwi Yang, Sebastian Gehlert   +5 more
doaj   +1 more source

Patulin Alters Insulin Signaling and Metabolic Flexibility in HepG2 and HEK293 Cells

Toxins, 2023
Non-communicable diseases (NCDs) have risen rapidly worldwide, sparking interest in causative agents and pathways. Patulin (PAT), a xenobiotic found in fruit products contaminated by molds, is postulated to be diabetogenic in animals, but little is known
Yashodani Pillay, Savania Nagiah, Anil Chuturgoon   +2 more
doaj   +1 more source

Metabolic Flexibility and Its Impact on Health Outcomes

Mayo Clinic Proceedings, 2022
A metabolically flexible state exists when there is a rapid switch between glucose and fatty acids during the transition between the fed and fasting state. This flexibility in fuel choice serves to prevent hyperglycemia following a meal and simultaneously ensures an adequate amount of blood glucose is available for delivery to the brain and exclusively
Biff F, Palmer, Deborah J, Clegg
openaire   +2 more sources

Development of the MetFlex Index™: associations between cardiometabolic risk factors and fitness using a novel approach with blood lactate

Frontiers in Physiology
IntroductionCardiometabolic health is declining in the U.S. and anticipated to worsen over the next 30 years. Measurements of cardiometabolic health include blood metabolite profiles. One such metabolite is blood lactate.
Bryan Jasker, Bryan Jasker, Daniel Dodd, Clara B. Peek, Clara B. Peek, Garett J. Griffith   +5 more
doaj   +1 more source