Results 101 to 110 of about 159,394 (302)

metabolomic

, 2019
Metabolomi
Anne GOUBET (6944561)
core   +1 more source

Metabolic analysis of the interaction between plants and herbivores [PDF]

, 2008
Insect herbivores by necessity have to deal with a large arsenal of plant defence metabolites. The levels of defence compounds may be increased by insect damage.
Marsden-Edwards, Emma, Goodacre, R., Jeroen J. Jansen, Jansen, J.J., Jansen, J.M., Van der Putten, W.H., Allwood, J. William, Jansen, Jeroen J., van der Putten, Wim H., Van Dam, N.M., van Dam, M., Royston Goodacre, Dam, N.M. van, Dam, M., van, Goodacre, Royston, Nicole M. van Dam, Wim H. van der Putten, Allwood, J.W., Putten, W.H., van der, J. William Allwood, Emma Marsden-Edwards, van Dam, Nicole M., Marsden-Edwards, E., Wim H. Putten, Nicole M. Dam, Putten, W.H. van der   +25 more
core   +3 more sources

Comparative transcriptomic and metabolomic analysis reveals mechanisms of selenium-regulated anthocyanin synthesis in waxy maize (Zea mays L.)

Frontiers in Plant Science
Anthocyanins in maize (Zea mays L.) kernels determine the plant’s color and can enhance its resistance. Selenium (Se) significantly impacts plant growth, development, and secondary metabolic regulation.
Guangyu Guo, Guangyu Guo, Yufeng Wang, Baoku Zhang, Haoran Yu, Liang Li, Guanglu Cao, Baicui Chen, Chengxin Li, Fanshan Bu, Song Teng, Qingtao Yu, Mingbo Gao, Baiwen Jiang, Kejun Yang   +14 more
doaj   +1 more source

Oligomeric Proanthocyanidins Counteracts the Negative Effects of High Level of Dietary Histamine on American Eel (Anguilla rostrata)

Frontiers in Marine Science, 2020
The economic loss of intestinal inflammation by histamine in diet has caused concern in eel culture; it is urgent to develop a natural feed additive to alleviate the negative effects of high-level dietary histamine.
Shaowei Zhai, Yue Wang, Yingxia He, Xuehao Chen   +3 more
doaj   +1 more source

TRAIP Mediates Alcohol‐Induced Liver Injury through Regulating β‐catenin Ubiquitin Degradation via Direct Interaction

Advanced Science, EarlyView.
This study reveals that NF‐κB1‐driven TRAIP upregulation in ALD correlates with disease severity. Mechanistically, TRAIP directly binds β‐catenin via its CC domain and promotes its K48‐linked ubiquitination and degradation, which is independent of the GSK3β/β‐TrCP pathway.
Zhan Wu, Mingjiang Liu, Lijuan Liao, Zhaohong Mo, Wenli Xu, Linfeng Mao, Yubing Chen, Qiuli Xie, Ming Yao, Shilian Chen, Stephen Tomlinson, Sebastian Mueller, Songqing He, Guandou Yuan   +13 more
wiley   +1 more source

Metabolomics in spondylarthritis

BMC Rheumatology
Abstract Background and aim Spondyloarthritides (SpA) are common entities of the inflammatory rheumatic type. There are still 3 relevant problems in everyday clinical practice: early disease detection, cardiovascular risk assessment, and less so, disease activity measurement.
Patschan, Susann, Remus, Constantin, Claus, Inga, Hoffmeister, Meike, Ritter, Oliver, Patschan, Daniel   +5 more
openaire   +2 more sources

Integrated multi-omics landscape of non-small cell lung cancer with distant metastasis

Frontiers in Immunology
BackgroundDistant metastasis is one of the important factors affecting the prognosis of lung cancer patients. Extracellular vesicles (EVs) play an important role in the occurrence, development, and metastasis of cancer.
Teng He, Ting Jiang, Xiaoyuan Sun, Fang Yang, Dan Zhang, Shan Yao, Jiangrong Liao, Xueling Wu   +7 more
doaj   +1 more source

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

Advanced Science, EarlyView.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang, Yuchuan Chen, Jiayuan Wan, Jianzheng Yang, Lijian Chen, Qingyuan Li, Anding Zhou, Nian Zhou, Jiuyang Ding, Qi Wang, Jian Sun   +10 more
wiley   +1 more source

Integrated transcriptomic and metabolomic analyses reveal a novel mechanism of resistance to Colletotrichum fructicola in pear

Journal of Integrative Agriculture
Pear anthracnose, caused by Colletotrichum fructicola, is a devastating disease that seriously affects most pear varieties, compromising their yield and quality. However, effective control of this pathogen is lacking.
Xiaomei Tang, Yue Wang, Yuqing Guo, Luoluo Xie, Wei Song, Ziwen Xiao, Ruichang Yin, Zhe Ye, Xueqiu Sun, Wenming Wang, Lun Liu, Zhenfeng Ye, Zhenghui Gao, Bing Jia   +13 more
doaj   +1 more source

UDP‐Glucose‐6‐Dehydrogenase Mediated O‐GlcNAcylation of Tight Junction Protein 1 Suppresses Metastasis in Renal Cell Carcinoma

Advanced Science, EarlyView.
Our research unveiled a regulatory paradigm wherein TRIM25 orchestrates the ubiquitin‐mediated degradation of UGDH. UGDH modulates the protein stability of TJP1 by regulating O‐GlcNAcylation levels, effectively impeding the metastasis of ccRCC. Our insights elevate UGDH to a pivotal biomarker and tumor suppressor, marking the first demonstration that ...
Xiaolin Chen, Yuhang Bao, Tao Liu, Jianhui Qiu, Yuanyuan Ma, Zedan Zhang, Chuandong Wang, Ruiyi Deng, Zheng Song, Tianyi He, Haode Liu, Jingcheng Zhou, Yizhou Wang, Kan Gong   +13 more
wiley   +1 more source