Results 21 to 30 of about 168,925 (309)

Anthropogenic Pressure and Lifestyle are the Underlying Cause of Pandemic Chronic Diseases [PDF]

Журнал Сибирского федерального университета: Серия Биология, 2019
Dramatic changes in the environment in recent decades have resulted in low-nutrient food and excessive intake of heavy metals and toxins through air, drinking water, and dietary habits. Non-communicable diseases (NCD), which are responsible for almost 70%
Dimitris Tsoukalas, Evangelia Sarandi, Aristides Tsatsakis, Daniela Calina   +3 more
doaj   +1 more source

Cardiovascular Metabolomics [PDF]

Circulation Research, 2018
Disturbances in cardiac metabolism underlie most cardiovascular diseases. Metabolomics, one of the newer omics technologies, has emerged as a powerful tool for defining changes in both global and cardiac-specific metabolism that occur across a spectrum of cardiovascular disease states.
Robert W, McGarrah, Scott B, Crown, Guo-Fang, Zhang, Svati H, Shah, Christopher B, Newgard   +4 more
openaire   +2 more sources

Indigenous and commercial isolates of arbuscular mycorrhizal fungi display differential effects in Pyrus betulaefolia roots and elicit divergent transcriptomic and metabolomic responses

Frontiers in Plant Science, 2023
BackgroundArbuscular mycorrhizal fungi (AMF) are beneficial soil fungi which can effectively help plants with acquisition of mineral nutrients and water and promote their growth and development.
Yadong Shao, Shangtao Jiang, Haiying Peng, Han Li, Peigen Li, Rou Jiang, Wenyi Fang, Tingsu Chen, Gaofei Jiang, Tianjie Yang, Savithri U. Nambeesan, Yangchun Xu, Caixia Dong   +12 more
doaj   +1 more source

The metabolome of human milk is altered differentially by Holder pasteurization and high hydrostatic pressure processing

Frontiers in Nutrition, 2023
The milk metabolome is composed of hundreds of molecules that can impact infant development. In preterm infants, sterilized donor milk (DM) is frequently used for their feeding.
Léa Chantal Tran, Lucie Marousez, Marie De Lamballerie, Scott McCulloch, Emmanuel Hermann, Frédéric Gottrand, Frédéric Gottrand, Delphine Ley, Delphine Ley, Jean Lesage   +9 more
doaj   +1 more source

The metabolomic profile of gamma-irradiated human hepatoma and muscle cells reveals metabolic changes consistent with the Warburg effect [PDF]

, 2016
The two human cell lines HepG2 from hepatoma and HMCL-7304 from striated muscle were γ-irradiated with doses between 0 and 4 Gy. Abundant γH2AX foci were observed at 4 Gy after 4 h of culture post-irradiation.
Idle, J. R., Treves, Susan, Treves, S., Beyoğlu, Diren, Keogh, Adrian, Wang, M., Idle, Jeffrey, Idle, Jeffrey R., Beyoğlu, D., Min Wang, Diren Beyoğlu, Wang, Min, Adrian Keogh, Susan Treves, Jeffrey R. Idle, Keogh, A., Treves S, Beyoğlu D, Keogh A, Wang M, Idle JR   +20 more
core   +3 more sources

Metabolomic Profiling of Adults with Congenital Heart Disease

, 2021
Metabolomic analysis may provide an integrated assessment in genetically and pathologically heterogeneous populations. We used metabolomic analysis to gain mechanistic insight into the small and diverse population of adults with congenital heart disease (
Alexander Opotowsky, Shelby Kutty, Cedric Manlhiot, Jong-Mi Ko, Erland Arning, Angela Weingarten, Teodoro Bottiglieri, Ari Cedars   +7 more
core   +1 more source

Polymorphie DNA repair genes XRCC1 and XRCC3 and the risk for cervical cancer in Brazilian patients

Brazilian Journal of Oncology, 2017
Background: DNA repair genes play a key role in maintaining genomic stability and integrity. DNA repair gene polymorphisms, such as X-ray repair cross-complementing group 1 and 3 genes (XRCC1 and XRCC3), are implicated to contribute to ...
Fabricio Colacino-Silva, João Paulo Ferreira de Oliveira Kleine, Márcia Batista Salzgeber, Rodrigo de Aquino Castro, Manoel João Batista Castello Girão, Ismael Dale Cotrim Guerreiro da Silva, Paulo D’Amora   +6 more
doaj   +1 more source

Extraction for Metabolomics: Access to The Metabolome

Phytochemical Analysis, 2014
ABSTRACTIntroductionThe value of information obtained from a metabolomic study depends on how much of the metabolome is present in analysed samples. Thus, only a comprehensive and reproducible extraction method will provide reliable data because the metabolites that will be measured are those that were extracted and all conclusions will be built around
Mushtaq, M.Y., Choi, Y.H., Verpoorte, R., Wilson, E.G.   +3 more
openaire   +3 more sources

Targeted Metabolomics [PDF]

Current Protocols in Molecular Biology, 2012
AbstractThe metabolome is the terminal downstream product of the genome and consists of the total complement of all the low‐molecular‐weight molecules (metabolites) in a cell, tissue, or organism. Metabolomics aims to measure a wide breadth of small molecules in the context of physiological stimuli or disease states.
Lee D, Roberts, Amanda L, Souza, Robert E, Gerszten, Clary B, Clish   +3 more
openaire   +2 more sources

Metabolomics in Otorhinolaryngology

Frontiers in Molecular Biosciences, 2022
Otorhinolaryngology (Ear, Nose and Throat-ENT) focuses on inflammatory, immunological, infectious, and neoplastic disorders of the head and neck and on their medical and surgical therapy. The fields of interest of this discipline are the ear, the nose and its paranasal sinuses, the oral cavity, the pharynx, the larynx, and the neck.
Noto, Antonio, Piras, Cristina, Atzori, Luigi, Mussap, Michele, Albera, Andrea, Albera, Roberto, Casani, Augusto Pietro, Capobianco, Silvia, Fanos, Vassilios   +8 more
openaire   +5 more sources