Results 41 to 50 of about 159,394 (302)

Comparative Proteomic and Metabonomic Profiling of Buds with Different Flowering Capabilities Reveal Novel Regulatory Mechanisms of Flowering in Apple

Plants, 2023
Flower bud formation in the apple tree life cycle is associated with multiple biological processes. To explore the physiological and molecular mechanisms underlying the protein and metabolite changes in buds with different flowering capabilities ...
Shujin Wang, Xiaoping Chen, Sitong Liu, Xiaochen Zhang, Yu Li, Wei Shang, Jiahui Song, Jianwen Tian, Xiaolong Li, Libo Xing   +9 more
doaj   +1 more source

Metabolomics of a Superorganism [PDF]

The Journal of Nutrition, 2007
The human can be thought of as a human-microbe hybrid, and the health of this superorganism will be affected by intrinsic properties such as human genetics, diurnal cycles, and age and by extrinsic factors such as lifestyle choices (food and drink, drug intake) and the acquisition of a stable "healthy" gut microflora (the so-called microbiome ...
openaire   +4 more sources

Mass Spectrometry Imaging Reveals Elevated Glomerular ATP/AMP in Diabetes/obesity and Identifies Sphingomyelin as a Possible Mediator

EBioMedicine, 2016
AMP-activated protein kinase (AMPK) is suppressed in diabetes and may be due to a high ATP/AMP ratio, however the quantitation of nucleotides in vivo has been extremely difficult. Via matrix-assisted laser desorption/ionization mass spectrometry imaging (
Satoshi Miyamoto, Cheng-Chih Hsu, Gregory Hamm, Manjula Darshi, Maggie Diamond-Stanic, Anne-Emilie Declèves, Larkin Slater, Subramaniam Pennathur, Jonathan Stauber, Pieter C. Dorrestein, Kumar Sharma   +10 more
doaj   +1 more source

Metabolomics and Atherosclerosis [PDF]

Current Atherosclerosis Reports, 2010
Metabolites reflect the dynamic processes underlying cellular homeostasis. Recent advances in analytical chemistry and molecular biology have set the stage for metabolite profiling to help us understand complex molecular processes and physiology. Metabolomics is the comparative analysis of metabolite flux and how it relates to biological phenotypes. As
Sascha N, Goonewardena, Lisa E, Prevette, Ankit A, Desai   +2 more
openaire   +2 more sources

Supplementary Tables for: "Comparative targeted metabolomic profiles of porcine plasma and serum"

, 2023
<p>Supplementary Tables for: "Comparative targeted metabolomic profiles of porcine plasma and serum"</p ...
Bovo, Samuele, Galimberti, Giuliano, Dall'Olio, Stefania, Fanelli, Flaminia, Pagotto, Uberto, Fontanesi, Luca, Schiavo, Giuseppina, Bertolini, Francesca   +7 more
core   +1 more source

The Microbiome and Metabolomic Profile of the Transplanted Intestine with Long-Term Function

Biomedicines, 2022
We analyzed the fecal microbiome by deep sequencing of the 16S ribosomal genes and the metabolomic profiles of 43 intestinal transplant recipients to identify biomarkers of graft function.
Raffaelle Girlanda, Jedson R. Liggett, Meth Jayatilake, Alexander Kroemer, Juan Francisco Guerra, Jason Solomon Hawksworth, Pejman Radkani, Cal S. Matsumoto, Michael Zasloff, Thomas M. Fishbein   +9 more
doaj   +1 more source

Stability of Metabolomic Content during Sample Preparation: Blood and Brain Tissues

, 2022
Thermal and enzymatic reactions can significantly change the tissue metabolomic content during the sample preparation. In this work, we evaluated the stability of metabolites in human whole blood, serum, and rat brain, as well as in metabolomic extracts ...
Lyudmila V. Yanshole, Tsentalovich, Yuri P., Maxim V. Fomenko, Yuri P. Tsentalovich, Fomenko, Maxim V., Yanshole, Lyudmila V.   +5 more
core   +1 more source

Access to Anti-Biofilm Compounds from Endolichenic Fungi Using a Bioguided Networking Screening

Journal of Fungi, 2022
Endolichenic microorganisms represent a new source of bioactive natural compounds. Lichens, resulting from a symbiotic association between algae or cyanobacteria and fungi, constitute an original ecological niche for these microorganisms.
Seinde Toure, Marion Millot, Lucie Ory, Catherine Roullier, Zineb Khaldi, Valentin Pichon, Marion Girardot, Christine Imbert, Lengo Mambu   +8 more
doaj   +1 more source

The Role of Amino Acids in Tuberculosis Infection: A Literature Review

Metabolites, 2022
Recently, there was an abundance of studies being conducted on the metabolomic profiling of tuberculosis patients. Amino acids are critical metabolites for the immune system, as they might contribute to providing nutrients for the host intracellular ...
Fiki Amalia, Mas Rizky A. A. Syamsunarno, Rima Destya Triatin, Siti Nur Fatimah, Lidya Chaidir, Tri Hanggono Achmad   +5 more
doaj   +1 more source

Metabolomics-based treatment for chronic diseases: results from a multidisciplinary clinical study

BMJ Nutrition, Prevention & Health
Background Non-communicable diseases (NCDs), known as chronic diseases, significantly impact patients’ quality of life (QoL) and increase medical expenses.
Aristidis Tsatsakis, Dimitris Tsoukalas, Evangelia Sarandi, Vassilleios Fragoulakis, Symeon Xenidis, Maria Mhliopoulou, Maria Charta, Efstathia Paramera, Evangelos Papakonstantinou   +8 more
doaj   +1 more source