Diagnostic and Prognostic Research, 2017 Background Disease prevalence is rarely explicitly considered in the early stages of the development of novel prognostic tests. Rather, researchers use the area under the receiver operating characteristic (AUROC) as the key metric to gauge and report ...
Grégoire Thomas +3 more
doaj +1 more source
Metabolite changes in blood predict the onset of tuberculosis
, 2018 Immunogenetics and cellular immunology of bacterial infectious ...
Boom, W.H. +21 more
core +1 more source
Medical Journal of Babylon, 2023 The relationship between microbiome and metabolomics by studying the microbiota living in the human body and studying their effects on the concentration of metabolites, also to study effects of microbiota colonization on other bacteria or living organism entering the body.
Noor S K Al-Khafaji +10 more
openaire +2 more sources
Immunometabolism is a key factor for the persistent spontaneous elite control of HIV-1 infection [PDF]
, 2019 Approximately 25% of elite controllers (ECs) lose their virological control by mechanisms that are only partially known. Recently, immunovirological and proteomic factors have been associated to the loss of spontaneous control. Our aim was to perform a
Alba, Verónica +12 more
core +2 more sources
Metabolomics-based biomarker discovery for bee health monitoring : a proof of concept study concerning nutritional stress in Bombus terrestris [PDF]
, 2019 Bee pollinators are exposed to multiple natural and anthropogenic stressors. Understanding the effects of a single stressor in the complex environmental context of antagonistic/synergistic interactions is critical to pollinator monitoring and may serve ...
Meeus, Ivan +5 more
core +2 more sources
Plasticizer degradation by marine bacterial isolates : a proteogenomic and metabolomic characterization [PDF]
, 2020 Many commercial plasticizers are toxic endocrine-disrupting chemicals that are added to plastics during manufacturing and may leach out once they reach the environment.
Bosch, Rafael +3 more
core +3 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Molecules, 2022 The eggplant is a fruit rich in natural products and produced worldwide. However, its cultivation generates a large amount of scarcely used agricultural residues with poor chemical characterization.
Laura Aracely Contreras-Angulo +7 more
doaj +1 more source
Optimized Analytical Procedures for the Untargeted Metabolomic Profiling of Human Urine and Plasma by Combining Hydrophilic Interaction (HILIC) and Reverse-Phase Liquid Chromatography (RPLC)-Mass Spectrometry. [PDF]
, 2015 Profiling of body fluids is crucial for monitoring and discovering metabolic markers of health and disease and for providing insights into human physiology.
Contrepois, Kévin +2 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source