Results 51 to 60 of about 159,394 (302)

Application of clinical blood metabogram for diagnosis of early-stage Parkinson’s disease: a pilot study

Frontiers in Molecular Biosciences
In terms of time, cost, and reproducibility of clinical laboratory tests, a mass spectrometric clinical blood metabogram (CBM) enables the investigation of the blood metabolome.
Petr G. Lokhov, Oxana P. Trifonova, Elena E. Balashova, Dmitry L. Maslov, Michael V. Ugrumov, Alexander I. Archakov   +5 more
doaj   +1 more source

Targeted Metabolomic Analysis of Serum Fatty Acids for the Prediction of Autoimmune Diseases

Frontiers in Molecular Biosciences, 2019
Autoimmune diseases (ADs) are rapidly increasing worldwide and accumulating data support a key role of disrupted metabolism in ADs. This study aimed to identify an improved combination of Total Fatty Acids (TFAs) biomarkers as a predictive factor for the
Dimitris Tsoukalas, Dimitris Tsoukalas, Dimitris Tsoukalas, Vassileios Fragoulakis, Evangelia Sarandi, Evangelia Sarandi, Anca Oana Docea, Evangelos Papakonstaninou, Gerasimos Tsilimidos, Chrysanthi Anamaterou, Persefoni Fragkiadaki, Michael Aschner, Aristidis Tsatsakis, Aristidis Tsatsakis, Nikolaos Drakoulis, Daniela Calina   +15 more
doaj   +1 more source

Untargeted and targeted metabolomics profiling reveals the underlying pathogenesis and abnormal arachidonic acid metabolism in laying hens with fatty liver hemorrhagic syndrome

Poultry Science, 2021
: As a metabolic disease, fatty liver hemorrhagic syndrome (FLHS) has become the major factor responsible for the noninfectious cause of mortality in laying hens, which lead to huge economic losses to poultry industry.
Jiacheng Meng, Ning Ma, Hailong Liu, Jing Liu, Juxiang Liu, Jianping Wang, Xin He, Xinghua Zhao   +7 more
doaj   +1 more source

A novel method for interrogating receiver operating characteristic curves for assessing prognostic tests

Diagnostic and Prognostic Research, 2017
Background Disease prevalence is rarely explicitly considered in the early stages of the development of novel prognostic tests. Rather, researchers use the area under the receiver operating characteristic (AUROC) as the key metric to gauge and report ...
Grégoire Thomas, Louise C. Kenny, Philip N. Baker, Robin Tuytten   +3 more
doaj   +1 more source

Metabolomics in oncology

Cancer Reports, 2023
AbstractBackgroundOncogenic transformation alters intracellular metabolism and contributes to the growth of malignant cells. Metabolomics, or the study of small molecules, can reveal insight about cancer progression that other biomarker studies cannot.
Gurparsad Singh Suri, Gurleen Kaur, Giuseppina M. Carbone, Dheeraj Shinde   +3 more
openaire   +3 more sources

Analysis of the main antioxidant enzymes in the roots of Tamarix ramosissima under NaCl stress by applying exogenous potassium (K+)

Frontiers in Plant Science, 2023
IntroductionSalinization affects more than 25% of the world's arable land, and Tamarix ramosissima Ledeb (T. ramosissima), the representative of Tamarix plants, is widely grown in salinized soil.
Yahui Chen, Yahui Chen, Yahui Chen, Yahui Chen, Haijia Li, Shiyang Zhang, Shiyang Zhang, Shanfeng Du, Jinchi Zhang, Zhizhong Song, Jiang Jiang   +10 more
doaj   +1 more source

Cell Metabolomics [PDF]

OMICS: A Journal of Integrative Biology, 2013
Abstract Metabolomics technologies enable the examination and identification of endogenous biochemical reaction products, revealing information on the precise metabolic pathways and processes within a living cell. Metabolism is either directly or indirectly involved with every aspect of cell function, and metabolomics is thus believed
Aihua, Zhang, Hui, Sun, Hongying, Xu, Shi, Qiu, Xijun, Wang   +4 more
openaire   +2 more sources

Identification of Novel Biomarkers in Late Preterm Neonates with Respiratory Distress Syndrome (RDS) Using Urinary Metabolomic Analysis

, 2023
Urine metabolomics is gaining traction as a means of identifying metabolic signatures associated with health and disease states. Thirty-one (31) late preterm (LP) neonates admitted to the neonatal intensive care unit (NICU) and 23 age-matched healthy LPs
Irene Christopoulou, Konstantina Matzarapi, Anastasia Varvarigou, Eirini Kostopoulou, Styliani A. Chasapi, Georgios A. Spyroulias   +5 more
core   +1 more source

Metabolic imprint induced by seed halo-priming promotes a differential physiological performance in two contrasting quinoa ecotypes

Frontiers in Plant Science, 2023
“Memory imprint” refers to the process when prior exposure to stress prepares the plant for subsequent stress episodes. Seed priming is a strategy to change the performance of seedlings to cope with stress; however, mechanisms associated with the ...
Leonardo Cifuentes, Máximo González, Katherine Pinto-Irish, Rodrigo Álvarez, Teodoro Coba de la Peña, Enrique Ostria-Gallardo, Nicolás Franck, Susana Fischer, Gabriel Barros, Catalina Castro, José Ortiz, Carolina Sanhueza, Néstor Fernández Del-Saz, Luisa Bascunan-Godoy, Patricio A. Castro   +14 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source